Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   E8M05_RS10740 Genome accession   NZ_CP039457
Coordinates   2059834..2061093 (-) Length   419 a.a.
NCBI ID   WP_003066899.1    Uniprot ID   E0PGE8
Organism   Streptococcus pasteurianus strain WUSP067     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2054834..2066093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M05_RS11760 - 2056400..2056528 (-) 129 WP_259293846.1 hypothetical protein -
  E8M05_RS10715 (E8M05_10705) - 2056620..2056925 (-) 306 WP_003066884.1 DUF1292 domain-containing protein -
  E8M05_RS10720 (E8M05_10710) ruvX 2056958..2057377 (-) 420 WP_013852327.1 Holliday junction resolvase RuvX -
  E8M05_RS10725 (E8M05_10715) - 2057374..2057643 (-) 270 WP_003066890.1 IreB family regulatory phosphoprotein -
  E8M05_RS10730 (E8M05_10720) spx 2057962..2058360 (-) 399 WP_003066893.1 transcriptional regulator Spx -
  E8M05_RS10735 (E8M05_10725) recA 2058630..2059784 (-) 1155 WP_003066896.1 recombinase RecA -
  E8M05_RS10740 (E8M05_10730) cinA 2059834..2061093 (-) 1260 WP_003066899.1 competence/damage-inducible protein A Machinery gene
  E8M05_RS10745 (E8M05_10735) - 2061225..2062415 (-) 1191 WP_048790986.1 MFS transporter -
  E8M05_RS11260 - 2062575..2062748 (-) 174 WP_048790985.1 hypothetical protein -
  E8M05_RS11685 - 2062798..2063007 (-) 210 WP_231729899.1 hypothetical protein -
  E8M05_RS11690 - 2062965..2063246 (-) 282 WP_003066911.1 hypothetical protein -
  E8M05_RS11695 - 2063316..2063525 (-) 210 WP_003066913.1 hypothetical protein -
  E8M05_RS11700 - 2063547..2063723 (-) 177 WP_003066916.1 hypothetical protein -
  E8M05_RS10760 (E8M05_10750) - 2063871..2064722 (+) 852 WP_003066919.1 helix-turn-helix transcriptional regulator -
  E8M05_RS10765 (E8M05_10755) ruvA 2064802..2065395 (-) 594 WP_003066922.1 Holliday junction branch migration protein RuvA Machinery gene

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45423.82 Da        Isoelectric Point: 5.1768

>NTDB_id=317872 E8M05_RS10740 WP_003066899.1 2059834..2061093(-) (cinA) [Streptococcus pasteurianus strain WUSP067]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSVIDLASKRSELVVLCGGLGPTEDDLTKQT
LAKYLGRDLVFDEQANKRLDEFFATRPQFARTANNERQAQLIEGSIPLQNSTGLAVGGVLEVNGVTYVVLPGPPSELKPM
VLDSLVPLLSGDHKQLYSRVLRFFGIGESQLVTVLADLIDNQTDPTIAPYAKTGEVTLRLSTKADDVTSAKAKLDALEHK
ILAKKTLNSIPLEQLLYGYGDDNNMARVVFDLLKEKHKTITAAESLTAGLFQSSIADFSGSSAVFNGGFVTYSIEEKSKM
LHIPLKDLQEHGVVSHFTAEKMAEQSRLLTDADFGIGLTGVAGPDSLEGHPAGTVFIGIATREKVHSIRVVIGGRSRSDV
RYIATLYAFNLVRQALLQG

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=317872 E8M05_RS10740 WP_003066899.1 2059834..2061093(-) (cinA) [Streptococcus pasteurianus strain WUSP067]
ATGAAAGCTGAAATCATTGCTGTGGGAACAGAAATTCTAACAGGACAAATCACAAATACAAATGCTCAATTTTTATCGGA
AGAATTTGCCAAGTTAGGAATTGATGTGTTCTTTCAAACAGCTGTTGGTGATAATGAAGAACGTCTTTTATCAGTTATTG
ATTTAGCAAGCAAGCGAAGTGAATTAGTTGTCTTATGTGGAGGGCTTGGTCCGACAGAAGACGATTTAACAAAACAAACG
TTAGCAAAATATTTGGGACGCGATTTAGTCTTTGATGAACAAGCTAACAAGCGTTTGGACGAATTTTTTGCGACACGTCC
GCAGTTTGCTAGAACGGCTAATAACGAACGTCAAGCACAGCTGATTGAAGGGTCAATACCGTTGCAAAATAGCACTGGTT
TGGCTGTTGGTGGCGTGCTAGAAGTAAATGGCGTGACCTACGTTGTTCTCCCTGGACCACCGAGTGAATTAAAACCAATG
GTATTGGATTCTCTAGTGCCTTTGTTGTCTGGAGACCATAAGCAGCTTTATTCACGTGTGTTGCGTTTCTTTGGGATTGG
TGAAAGCCAGTTAGTGACCGTCTTGGCAGATTTGATTGATAACCAAACAGACCCAACGATTGCTCCGTATGCGAAAACAG
GTGAGGTGACCCTTCGTTTATCAACCAAGGCAGATGATGTGACGTCAGCAAAAGCGAAATTGGATGCTCTAGAGCATAAA
ATTCTAGCCAAAAAAACATTAAATAGTATTCCTCTTGAACAGTTACTTTATGGCTACGGTGATGATAACAATATGGCGCG
TGTTGTTTTTGATTTGTTGAAAGAAAAGCACAAAACTATTACAGCTGCAGAAAGTTTGACCGCAGGGCTATTCCAATCTA
GTATCGCTGATTTTTCAGGGTCATCTGCAGTATTTAATGGCGGATTTGTGACGTATAGTATAGAAGAAAAATCAAAAATG
CTTCACATTCCTCTTAAAGATTTGCAAGAACATGGTGTAGTAAGTCACTTTACAGCTGAAAAAATGGCAGAGCAATCACG
TTTATTGACAGATGCTGATTTTGGTATCGGTTTGACAGGTGTTGCAGGACCAGATAGCTTAGAAGGACATCCAGCAGGAA
CAGTTTTCATTGGTATTGCGACTAGAGAAAAAGTTCATTCTATTCGTGTTGTTATAGGTGGGCGAAGCCGTTCAGACGTC
CGTTATATTGCTACTTTATATGCTTTCAACTTAGTACGTCAAGCTTTATTACAAGGCTAA

Domains

Predicted by InterProScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Competence-damaged protein (CinA)

(264-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E0PGE8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.182

99.523

0.718
  cinA Streptococcus mitis SK321

71.292

99.761

0.711
  cinA Streptococcus mitis NCTC 12261

71.053

99.761

0.709
  cinA Streptococcus pneumoniae R6

70.335

99.761

0.702
  cinA Streptococcus pneumoniae Rx1

70.335

99.761

0.702
  cinA Streptococcus pneumoniae TIGR4

70.335

99.761

0.702
  cinA Streptococcus pneumoniae R36A

70.335

99.761

0.702
  cinA Streptococcus pneumoniae D39

70.096

99.761

0.699
  cinA Streptococcus suis isolate S10

53.846

99.284

0.535
  cinA Bacillus subtilis subsp. subtilis str. 168

45.498

100

0.458

Multiple sequence alignment