Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC   Type   Machinery gene
Locus tag   LL1196_RS12125 Genome accession   NZ_CP032148
Coordinates   2314101..2314451 (-) Length   116 a.a.
NCBI ID   WP_050574401.1    Uniprot ID   -
Organism   Lactococcus cremoris strain 1196     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2314551..2318953 2314101..2314451 flank 100


Gene organization within MGE regions


Location: 2314101..2318953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL1196_RS12125 (LL1196_2428) comGC 2314101..2314451 (-) 351 WP_050574401.1 competence type IV pilus major pilin ComGC Machinery gene
  LL1196_RS12130 (LL1196_2429) comGB 2314496..2315521 (-) 1026 WP_050574400.1 competence type IV pilus assembly protein ComGB Machinery gene
  LL1196_RS12135 (LL1196_2430) - 2315421..2316242 (-) 822 Protein_2361 ATPase, T2SS/T4P/T4SS family -
  LL1196_RS12140 (LL1196_2431) - 2316345..2317235 (+) 891 WP_205536422.1 IS982 family transposase -
  LL1196_RS12145 (LL1196_2432) comGA 2317217..2317408 (-) 192 WP_014573341.1 hypothetical protein Machinery gene

Sequence


Protein


Download         Length: 116 a.a.        Molecular weight: 13289.44 Da        Isoelectric Point: 7.2003

>NTDB_id=314103 LL1196_RS12125 WP_050574401.1 2314101..2314451(-) (comGC) [Lactococcus cremoris strain 1196]
MSKALSLIKIHGRKLWQKKQKAFTLIEMLIVLAIISILILLFVPNLIKEKAQVQKTGEAAVVKVVESQAQLYELDHDNDK
PNLSELLSAGMITQKQVTAYDDYYDQNKNEQRNFDD

Nucleotide


Download         Length: 351 bp        

>NTDB_id=314103 LL1196_RS12125 WP_050574401.1 2314101..2314451(-) (comGC) [Lactococcus cremoris strain 1196]
ATGAGCAAAGCTTTGTCATTAATTAAAATTCACGGAAGAAAGCTTTGGCAAAAAAAGCAAAAAGCATTTACCTTGATTGA
GATGTTAATTGTGTTGGCAATTATCAGTATTTTAATTTTGCTTTTTGTGCCAAATTTGATAAAAGAAAAAGCACAAGTTC
AAAAAACTGGTGAAGCAGCAGTAGTTAAAGTAGTTGAAAGTCAGGCACAACTTTATGAGTTGGATCATGATAATGATAAG
CCAAACCTATCAGAACTTTTAAGTGCGGGGATGATTACGCAAAAGCAAGTCACGGCCTATGATGATTACTATGACCAGAA
TAAAAATGAACAGCGCAATTTCGATGATTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Lactococcus lactis subsp. cremoris KW2

98.276

100

0.983

  comYC Streptococcus gordonii str. Challis substr. CH1

58.586

85.345

0.5

  comGC/cglC Streptococcus mitis SK321

55.882

87.931

0.491

  comGC/cglC Streptococcus pneumoniae R6

53.922

87.931

0.474

  comGC/cglC Streptococcus pneumoniae TIGR4

53.922

87.931

0.474

  comGC/cglC Streptococcus pneumoniae Rx1

53.922

87.931

0.474

  comGC/cglC Streptococcus pneumoniae D39

53.922

87.931

0.474

  comYC Streptococcus mutans UA140

59.14

80.172

0.474

  comYC Streptococcus mutans UA159

59.14

80.172

0.474

  comGC/cglC Streptococcus mitis NCTC 12261

55.67

83.621

0.466

  comYC Streptococcus suis isolate S10

56.818

75.862

0.431


Multiple sequence alignment