Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Ahae5227_RS15515 Genome accession   NZ_CP031988
Coordinates   3220390..3221616 (+) Length   408 a.a.
NCBI ID   WP_008942283.1    Uniprot ID   C0VHN4
Organism   Acinetobacter haemolyticus strain 5227     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3215390..3226616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Ahae5227_RS15480 (Ahae5227_15640) rimP 3215980..3216504 (-) 525 WP_005083847.1 ribosome maturation factor RimP -
  Ahae5227_RS15500 (Ahae5227_15660) secG 3217140..3217469 (-) 330 WP_004637686.1 preprotein translocase subunit SecG -
  Ahae5227_RS15505 (Ahae5227_15665) tpiA 3217482..3218273 (-) 792 WP_005088004.1 triose-phosphate isomerase -
  Ahae5227_RS15510 (Ahae5227_15670) pilB 3218650..3220365 (+) 1716 WP_008942284.1 type IV-A pilus assembly ATPase PilB Machinery gene
  Ahae5227_RS15515 (Ahae5227_15675) pilC 3220390..3221616 (+) 1227 WP_008942283.1 type II secretion system F family protein Machinery gene
  Ahae5227_RS17995 (Ahae5227_15680) pilD 3221616..3222473 (+) 858 WP_008942282.1 prepilin peptidase Machinery gene
  Ahae5227_RS15525 (Ahae5227_15685) coaE 3222475..3223080 (+) 606 WP_017395818.1 dephospho-CoA kinase -
  Ahae5227_RS15530 (Ahae5227_15690) - 3223077..3223988 (-) 912 WP_017394516.1 DMT family transporter -
  Ahae5227_RS15535 (Ahae5227_15700) rlmB 3224028..3224774 (-) 747 WP_004637678.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  Ahae5227_RS15540 (Ahae5227_15705) - 3224883..3225209 (-) 327 WP_004637677.1 pyrimidine/purine nucleoside phosphorylase -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44961.46 Da        Isoelectric Point: 9.7764

>NTDB_id=313184 Ahae5227_RS15515 WP_008942283.1 3220390..3221616(+) (pilC) [Acinetobacter haemolyticus strain 5227]
MAAKKAQMMPTFAYEGVDRKGAKIKGELPARNMALAKVTLRKQGVTIKNIREKRKNILEGLMKKKVTTLDITVFTRQLAT
MMKAGVPLVQGFEIVAEGLENPSMREVVLGLKGEVEGGNTFAGALRKYPQYFDNLFCSLVESGEQSGALETMLDRVAIYK
EKSELLKQKIKKAMKYPATVIVVAVIVTIILMVKVVPVFQDLFSSFGADLPAFTKMVVNMSVWMQEYWFILIIVVGVIIA
CFLEAKKRSKKFRDTLDKLALRLPIFGDLVYKAIIARYSRTLATTFAAGVPLIDALESTAGATNNVVYEEAVMKIREDVA
TGQQLQFAMRVSNRFPSMAIQMVAIGEESGALDSMLDKVATHFENEVDNAVDGLTAMMEPLIMAILGVLVGGLVIAMYLP
IFQMGSVV

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=313184 Ahae5227_RS15515 WP_008942283.1 3220390..3221616(+) (pilC) [Acinetobacter haemolyticus strain 5227]
ATGGCAGCTAAAAAAGCGCAAATGATGCCTACTTTTGCTTACGAAGGGGTAGATCGCAAAGGGGCAAAAATTAAAGGGGA
ATTACCAGCACGTAATATGGCTTTAGCCAAAGTCACATTACGCAAACAAGGGGTAACGATTAAGAACATTCGAGAAAAAC
GCAAAAACATTCTTGAAGGTTTGATGAAGAAGAAAGTCACCACCCTTGATATCACGGTATTTACACGCCAACTGGCAACC
ATGATGAAAGCTGGTGTCCCACTGGTGCAAGGCTTTGAAATCGTGGCTGAAGGTTTAGAGAATCCATCGATGCGGGAAGT
GGTACTTGGACTCAAAGGCGAAGTTGAAGGCGGTAATACCTTTGCGGGCGCATTAAGAAAATACCCACAATACTTTGACA
ACCTCTTTTGCTCTTTAGTTGAATCTGGTGAACAATCTGGTGCACTAGAAACCATGCTAGATCGCGTCGCGATTTATAAA
GAGAAAAGTGAGTTACTCAAACAAAAAATCAAAAAAGCCATGAAATATCCTGCGACAGTTATCGTGGTTGCAGTGATTGT
CACCATTATTTTGATGGTCAAGGTAGTCCCTGTTTTCCAAGATCTATTTAGCTCATTTGGTGCAGATTTACCTGCTTTTA
CCAAAATGGTCGTGAATATGTCCGTTTGGATGCAAGAATACTGGTTTATTTTAATTATCGTTGTCGGTGTGATTATTGCC
TGTTTTCTTGAAGCAAAAAAACGTAGTAAAAAATTCCGCGACACTCTTGATAAACTTGCATTACGCTTACCGATTTTTGG
TGATTTGGTTTATAAAGCAATTATTGCGCGTTATAGTCGTACACTTGCAACAACATTTGCAGCAGGGGTTCCATTGATTG
ATGCACTCGAATCAACGGCTGGTGCAACCAATAACGTTGTTTATGAAGAAGCCGTGATGAAAATTCGTGAAGATGTTGCT
ACAGGACAACAGTTACAATTTGCCATGCGTGTTTCTAATCGCTTTCCATCAATGGCGATTCAAATGGTCGCAATTGGTGA
AGAATCAGGTGCTTTAGATAGTATGCTTGATAAAGTTGCCACTCACTTCGAAAATGAAGTCGACAATGCGGTCGATGGCT
TAACCGCAATGATGGAGCCATTAATTATGGCAATTCTAGGAGTACTTGTGGGTGGTCTTGTTATCGCGATGTACCTTCCA
ATTTTCCAAATGGGTTCTGTGGTCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(74-197)

Type II secretion system (T2SS), protein F (T2SSF)

(279-400)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0VHN4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Acinetobacter baumannii D1279779

92.402

100

0.924
  pilC Acinetobacter baylyi ADP1

86.029

100

0.86
  pilC Pseudomonas stutzeri DSM 10701

61.179

99.755

0.61
  pilC Legionella pneumophila strain ERS1305867

52.84

99.265

0.525
  pilG Neisseria meningitidis 44/76-A

46.734

97.549

0.456
  pilG Neisseria gonorrhoeae MS11

46.734

97.549

0.456
  pilC Vibrio cholerae strain A1552

41.032

99.755

0.409
  pilC Vibrio campbellii strain DS40M4

41.089

99.02

0.407
  pilC Thermus thermophilus HB27

36.908

98.284

0.363

Multiple sequence alignment