Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DUN60_RS11595 Genome accession   NZ_CP031055
Coordinates   2659601..2660830 (+) Length   409 a.a.
NCBI ID   WP_054547485.1    Uniprot ID   A0A837NSH7
Organism   Vibrio splendidus strain Vibrio sp     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2654601..2665830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DUN60_RS11575 ampD 2655598..2656146 (-) 549 WP_114633998.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DUN60_RS11580 nadC 2656282..2657172 (+) 891 WP_114633999.1 carboxylating nicotinate-nucleotide diphosphorylase -
  DUN60_RS11585 pilA 2657428..2657901 (+) 474 WP_054547487.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DUN60_RS11590 pilB 2657901..2659586 (+) 1686 WP_054547486.1 type IV-A pilus assembly ATPase PilB Machinery gene
  DUN60_RS11595 pilC 2659601..2660830 (+) 1230 WP_054547485.1 type II secretion system F family protein Machinery gene
  DUN60_RS11600 pilD 2660898..2661767 (+) 870 WP_114634000.1 A24 family peptidase Machinery gene
  DUN60_RS11605 coaE 2661770..2662384 (+) 615 WP_054547484.1 dephospho-CoA kinase -
  DUN60_RS11610 zapD 2662411..2663151 (+) 741 WP_017087400.1 cell division protein ZapD -
  DUN60_RS11615 yacG 2663233..2663430 (+) 198 WP_004735515.1 DNA gyrase inhibitor YacG -
  DUN60_RS11620 rplS 2663757..2664110 (-) 354 WP_004735514.1 50S ribosomal protein L19 -
  DUN60_RS11625 trmD 2664170..2664910 (-) 741 WP_004735512.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  DUN60_RS11630 rimM 2664937..2665491 (-) 555 WP_004735510.1 ribosome maturation factor RimM -
  DUN60_RS11635 rpsP 2665516..2665764 (-) 249 WP_004735508.1 30S ribosomal protein S16 -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45338.27 Da        Isoelectric Point: 10.2353

>NTDB_id=302964 DUN60_RS11595 WP_054547485.1 2659601..2660830(+) (pilC) [Vibrio splendidus strain Vibrio sp]
MSSKSKQSQLKNYHWKGINSSGKKVSGQSLALTELEVREKLKEQHIQIKKIKKKSISAITRLTHRVKAKDITILTRQLAT
MLATGVPIVQAIKLVSDNHRKAEMKSILSHICKGVEAGTPISKAMRTASRHFDDLYTDLVATGELSGNLAQVFERLATYR
EKSEQLKSKVIKALIYPAMVVAVALTVSYLMLTMVIPEFESMFSGFGADLPWFTQQVLYLSHWMQAYSFYSAIGVGLLIL
SFQQLRQRSYSIRLSTSRLGLRFPILGAVITKASIAKFSRTLSTSFSSGIPILTSLKTTAKTAGNLHYESAIIEVHRETA
AGMPMYIAMRNTNAFPEMVLQMVMIGEESGNLDDMLNKVASIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLP
IFNLMSVLG

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=302964 DUN60_RS11595 WP_054547485.1 2659601..2660830(+) (pilC) [Vibrio splendidus strain Vibrio sp]
ATGAGTAGTAAAAGCAAACAATCACAACTAAAAAACTACCATTGGAAGGGAATCAATAGTTCAGGCAAGAAAGTATCAGG
GCAGAGCTTAGCGCTCACCGAATTAGAAGTGCGAGAGAAGCTCAAAGAACAGCACATTCAGATTAAGAAAATCAAAAAGA
AAAGCATCTCAGCAATCACTCGTTTAACCCATCGAGTCAAAGCCAAAGATATCACTATTTTGACTCGCCAACTGGCTACC
ATGTTGGCTACTGGTGTGCCCATCGTACAAGCCATCAAGCTAGTGTCAGACAATCACCGCAAAGCAGAAATGAAATCGAT
TTTATCGCACATCTGCAAAGGTGTAGAAGCCGGCACGCCAATCTCAAAAGCGATGCGAACCGCAAGCCGCCACTTTGATG
ACCTCTATACCGACTTGGTCGCGACAGGCGAACTCTCCGGCAACCTTGCACAAGTATTTGAACGCTTGGCGACCTATCGA
GAAAAGAGCGAGCAACTAAAATCCAAGGTTATAAAGGCGCTCATCTACCCAGCAATGGTTGTAGCGGTCGCCCTTACCGT
TTCCTATTTAATGCTGACCATGGTCATCCCTGAATTTGAATCGATGTTTTCTGGTTTCGGAGCAGACTTACCTTGGTTCA
CCCAGCAAGTGCTTTATCTTTCCCATTGGATGCAGGCTTATAGTTTCTATAGTGCCATCGGTGTTGGTTTATTAATTCTG
TCTTTTCAGCAGCTGCGTCAGCGATCTTACTCGATTCGACTTTCAACCAGTCGTCTTGGTTTACGCTTCCCTATCTTGGG
TGCTGTCATCACTAAGGCATCAATTGCAAAGTTCAGCCGAACGCTATCAACCAGTTTTAGTTCTGGGATTCCTATCTTAA
CCAGCCTTAAAACAACGGCTAAAACGGCGGGTAATCTACATTATGAATCGGCCATCATCGAGGTTCACCGTGAGACTGCT
GCTGGCATGCCGATGTACATTGCAATGCGCAATACCAATGCCTTCCCGGAGATGGTTTTGCAGATGGTGATGATTGGTGA
AGAGTCCGGAAATCTTGATGATATGCTCAATAAAGTCGCTTCCATTTACGAGTTCGAAGTAGACAACACCGTCGATAACC
TAGGCAAGATTCTAGAGCCACTGATCATCGTATTTTTAGGCACCGTAGTTGGTGGACTTGTTGTCGCGATGTACTTACCG
ATCTTTAATCTTATGAGTGTGTTAGGATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(75-197)

Type II secretion system (T2SS), protein F (T2SSF)

(278-400)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A837NSH7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

80.75

97.8

0.79
  pilC Vibrio campbellii strain DS40M4

74.384

99.267

0.738
  pilC Acinetobacter baylyi ADP1

42.298

100

0.423
  pilC Acinetobacter baumannii D1279779

42.327

98.778

0.418
  pilC Legionella pneumophila strain ERS1305867

41.855

97.555

0.408
  pilG Neisseria gonorrhoeae MS11

41.542

98.289

0.408
  pilG Neisseria meningitidis 44/76-A

41.294

98.289

0.406
  pilC Pseudomonas stutzeri DSM 10701

40.347

98.778

0.399

Multiple sequence alignment