Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ETT70_RS08755 Genome accession   NZ_CP035429
Coordinates   1704320..1705591 (-) Length   423 a.a.
NCBI ID   WP_136112430.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emmNA     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1699320..1710591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT70_RS08730 (ETT70_08720) - 1701290..1701595 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  ETT70_RS08735 (ETT70_08725) ruvX 1701607..1702026 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  ETT70_RS08740 (ETT70_08730) - 1702023..1702292 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  ETT70_RS08745 (ETT70_08735) spx 1702406..1702804 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  ETT70_RS08750 (ETT70_08740) recA 1703095..1704231 (-) 1137 WP_002992179.1 recombinase RecA -
  ETT70_RS08755 (ETT70_08745) cinA 1704320..1705591 (-) 1272 WP_136112430.1 competence/damage-inducible protein A Machinery gene
  ETT70_RS08760 (ETT70_08750) - 1705660..1706220 (-) 561 WP_002992183.1 DNA-3-methyladenine glycosylase I -
  ETT70_RS08765 (ETT70_08755) ruvA 1706230..1706826 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  ETT70_RS08770 (ETT70_08760) - 1706828..1708048 (-) 1221 WP_002992187.1 MFS transporter -
  ETT70_RS08775 (ETT70_08765) hexB 1708059..1710041 (-) 1983 WP_136076690.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45985.69 Da        Isoelectric Point: 4.7648

>NTDB_id=301134 ETT70_RS08755 WP_136112430.1 1704320..1705591(-) (cinA) [Streptococcus pyogenes strain emmNA]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQT
LAKYLRRDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFEFLVKYDKSITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
CYIATLHAFNMVRKTLLKLENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=301134 ETT70_RS08755 WP_136112430.1 1704320..1705591(-) (cinA) [Streptococcus pyogenes strain emmNA]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTA
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGCGGTGGCCTTGGTCCAACGAAAGATGATTTAACCAAACAAACT
TTAGCAAAGTACCTTAGGAGAGACTTGGTTTATGATGAGCAAGCTTGTCAGAAACTAGATGACTTTTTTGCTAAGCGCAA
GCCTTCATCACGGACACCAAATAATGAGCGACAGGCACAAGTGATTGAAGGATCAATCCCTTTGCCAAATAAAACTGGTC
TTGCGGTTGGTGGGTTCATTACAGTCGATGGTATTAGTTATGTTGTCTTACCGGGTCCTCCAAGTGAATTGAAGCCGATG
GTAAATGAAGAATTGGTACCACTTCTGTCAAAACAATACAGTACATTGTATTCAAAGGTACTACGCTTTTTTGGTATTGG
GGAAAGTCAGTTGGTAACAGTCTTGTCAGATTTTATTGAGAATCAAACTGATCCAACCATTGCTCCGTATGCTAAGACTG
GCGAAGTGACTCTTCGCTTATCAACAAAAACTGAAAACCAAGCTCTGGCAGATAAAAAGTTAGGTCAGCTAGAAGCGCAG
CTACTATCCCGAAAAACTCTTGAAGGTCAACCCTTAGCTGATGTCTTTTATGGCTATGGGGAGGATAATTCCTTAGCGCG
TGAGACATTTGAGTTCTTAGTAAAATATGATAAGTCAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCCTTCCTTTAGAGGAGTTGAAATCGCATGGCGTTGTTAGTGCTTATACGGCCGAGGGGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGTCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGTCGTTTGGATGTG
TGCTATATCGCTACTTTACATGCCTTTAATATGGTCCGTAAAACTTTATTAAAACTTGAGAATTTGCTATAA

Domains

Predicted by InterProScan.

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

69.267

100

0.693
  cinA Streptococcus mitis SK321

69.305

98.582

0.683
  cinA Streptococcus mitis NCTC 12261

68.825

98.582

0.678
  cinA Streptococcus pneumoniae TIGR4

67.866

98.582

0.669
  cinA Streptococcus pneumoniae R36A

67.866

98.582

0.669
  cinA Streptococcus pneumoniae Rx1

67.866

98.582

0.669
  cinA Streptococcus pneumoniae R6

67.866

98.582

0.669
  cinA Streptococcus pneumoniae D39

67.626

98.582

0.667
  cinA Streptococcus suis isolate S10

52.885

98.345

0.52
  cinA Bacillus subtilis subsp. subtilis str. 168

46.411

98.818

0.459