NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	ETT70_RS08765	Genome accession	NZ_CP035429
Coordinates	1706230..1706826 (-)	Length	198 a.a.
NCBI ID	WP_002992186.1	Uniprot ID	P0DF49
Organism	Streptococcus pyogenes strain emmNA
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1701230..1711826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT70_RS08730 (ETT70_08720)	-	1701290..1701595 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
ETT70_RS08735 (ETT70_08725)	ruvX	1701607..1702026 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
ETT70_RS08740 (ETT70_08730)	-	1702023..1702292 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
ETT70_RS08745 (ETT70_08735)	spx	1702406..1702804 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
ETT70_RS08750 (ETT70_08740)	recA	1703095..1704231 (-)	1137	WP_002992179.1	recombinase RecA	-
ETT70_RS08755 (ETT70_08745)	cinA	1704320..1705591 (-)	1272	WP_136112430.1	competence/damage-inducible protein A	Machinery gene
ETT70_RS08760 (ETT70_08750)	-	1705660..1706220 (-)	561	WP_002992183.1	DNA-3-methyladenine glycosylase I	-
ETT70_RS08765 (ETT70_08755)	ruvA	1706230..1706826 (-)	597	WP_002992186.1	Holliday junction branch migration protein RuvA	Machinery gene
ETT70_RS08770 (ETT70_08760)	-	1706828..1708048 (-)	1221	WP_002992187.1	MFS transporter	-
ETT70_RS08775 (ETT70_08765)	hexB	1708059..1710041 (-)	1983	WP_136076690.1	DNA mismatch repair endonuclease MutL	Machinery gene
ETT70_RS08780 (ETT70_08770)	-	1710136..1711281 (-)	1146	WP_021299091.1	site-specific integrase	-
ETT70_RS08785 (ETT70_08775)	-	1711609..1711752 (+)	144	WP_002992192.1	putative holin-like toxin	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21879.26 Da Isoelectric Point: 6.8838

                                >NTDB_id=301135 ETT70_RS08765 WP_002992186.1 1706230..1706826(-) (ruvA) [Streptococcus pyogenes strain emmNA]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL

LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=301135 ETT70_RS08765 WP_002992186.1 1706230..1706826(-) (ruvA) [Streptococcus pyogenes strain emmNA]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG

AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA

CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae R6	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae D39	65.99	99.495	0.657
ruvA	Bacillus subtilis subsp. subtilis str. 168	40.887	100	0.419

Detailed information NTG0301135