Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DK877_RS00775 Genome accession   NZ_CP030023
Coordinates   122596..123546 (+) Length   316 a.a.
NCBI ID   WP_002936562.1    Uniprot ID   A0A142UQX7
Organism   Streptococcus suis strain ISU2414     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 117596..128546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK877_RS00765 (DK877_00785) - 121160..121525 (+) 366 WP_002936568.1 DUF1033 family protein -
  DK877_RS00770 (DK877_00790) - 121560..122510 (-) 951 WP_002936565.1 S66 peptidase family protein -
  DK877_RS00775 (DK877_00795) comYA 122596..123546 (+) 951 WP_002936562.1 competence type IV pilus ATPase ComGA Machinery gene
  DK877_RS00780 (DK877_00800) comYB 123458..124495 (+) 1038 WP_255195823.1 competence type IV pilus assembly protein ComGB Machinery gene
  DK877_RS00785 (DK877_00805) comYC 124497..124778 (+) 282 WP_009909092.1 competence type IV pilus major pilin ComGC Machinery gene
  DK877_RS00790 (DK877_00810) comGD 124759..125166 (+) 408 WP_009909093.1 competence type IV pilus minor pilin ComGD -
  DK877_RS00795 (DK877_00815) comYE 125138..125431 (+) 294 WP_024390433.1 competence type IV pilus minor pilin ComGE Machinery gene
  DK877_RS00800 (DK877_00820) comGF/cglF 125418..125852 (+) 435 WP_009909097.1 competence type IV pilus minor pilin ComGF Machinery gene
  DK877_RS00805 (DK877_00825) comGG 125830..126240 (+) 411 WP_009909099.1 competence type IV pilus minor pilin ComGG -
  DK877_RS00810 (DK877_00830) comYH 126297..127250 (+) 954 WP_024409299.1 class I SAM-dependent methyltransferase Machinery gene
  DK877_RS00815 (DK877_00835) - 127300..128487 (+) 1188 WP_013730078.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35490.39 Da        Isoelectric Point: 6.1802

>NTDB_id=298462 DK877_RS00775 WP_002936562.1 122596..123546(+) (comYA) [Streptococcus suis strain ISU2414]
MIQEKARKLIEKAVADRVSDIYLVPRGESYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIRGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=298462 DK877_RS00775 WP_002936562.1 122596..123546(+) (comYA) [Streptococcus suis strain ISU2414]
ATGATTCAAGAAAAAGCAAGAAAGTTGATTGAAAAGGCAGTGGCGGATAGGGTCAGTGACATTTATCTGGTTCCTCGCGG
GGAAAGCTATCAAGTTTATCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTCTGGTGATCCGCTTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCTGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGTCTGACAGGAGCGACGGTCTTCTCAACGGTTCACGCAAGGTCTATTTCGGGTGTCTAT
GCTCGTATGTTGGAATTGGGGGTCAGTCCTGAGGAGTTAAACAATGCCCTTCAAGGTATTGCCTATCAACGTTTAATCAG
GGGAGGAGGTGTGGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTAGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A142UQX7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.387

98.101

0.671
  comYA Streptococcus mutans UA159

67.524

98.418

0.665
  comYA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

53.943

100

0.541
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

87.658

0.364

Multiple sequence alignment