Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DK877_RS00780 Genome accession   NZ_CP030023
Coordinates   123458..124495 (+) Length   345 a.a.
NCBI ID   WP_255195823.1    Uniprot ID   -
Organism   Streptococcus suis strain ISU2414     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 118458..129495
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK877_RS00765 (DK877_00785) - 121160..121525 (+) 366 WP_002936568.1 DUF1033 family protein -
  DK877_RS00770 (DK877_00790) - 121560..122510 (-) 951 WP_002936565.1 S66 peptidase family protein -
  DK877_RS00775 (DK877_00795) comYA 122596..123546 (+) 951 WP_002936562.1 competence type IV pilus ATPase ComGA Machinery gene
  DK877_RS00780 (DK877_00800) comYB 123458..124495 (+) 1038 WP_255195823.1 competence type IV pilus assembly protein ComGB Machinery gene
  DK877_RS00785 (DK877_00805) comYC 124497..124778 (+) 282 WP_009909092.1 competence type IV pilus major pilin ComGC Machinery gene
  DK877_RS00790 (DK877_00810) comGD 124759..125166 (+) 408 WP_009909093.1 competence type IV pilus minor pilin ComGD -
  DK877_RS00795 (DK877_00815) comYE 125138..125431 (+) 294 WP_024390433.1 competence type IV pilus minor pilin ComGE Machinery gene
  DK877_RS00800 (DK877_00820) comGF/cglF 125418..125852 (+) 435 WP_009909097.1 competence type IV pilus minor pilin ComGF Machinery gene
  DK877_RS00805 (DK877_00825) comGG 125830..126240 (+) 411 WP_009909099.1 competence type IV pilus minor pilin ComGG -
  DK877_RS00810 (DK877_00830) comYH 126297..127250 (+) 954 WP_024409299.1 class I SAM-dependent methyltransferase Machinery gene
  DK877_RS00815 (DK877_00835) - 127300..128487 (+) 1188 WP_013730078.1 acetate kinase -
  DK877_RS00820 (DK877_00845) - 128802..129398 (+) 597 WP_009909104.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 39014.08 Da        Isoelectric Point: 9.4805

>NTDB_id=298463 DK877_RS00780 WP_255195823.1 123458..124495(+) (comYB) [Streptococcus suis strain ISU2414]
MRKLIAFLQQDISVLGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADLYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLFLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLSLVAVLAGMVWFRKTNKIKAFSRLAALPFFGKLIQIYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGGELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=298463 DK877_RS00780 WP_255195823.1 123458..124495(+) (comYB) [Streptococcus suis strain ISU2414]
ATGCGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTAGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCTAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCTCTATACCCAGGTCTTGTCAGACGGGTTGCTGGCAGGCAAACCCTTTTCGAGTTTACTG
GCAGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTGGCAGAAGTTCATGGTAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCGATTATCTTAC
TGGGTTTTCTGTTCTTGATTATGCTAGGCTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCTGCGACCATG
CTAATTAACCATCTGCCGACTATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGCGGTCTTGGCTGGTATGGTTTGGTT
TCGCAAAACCAACAAAATCAAGGCATTTTCCCGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAATCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGAAGTTTGATTGGGCAAGGCTTGGACCTGCCACAGATTGTGGGCTTGATGCAGGAG
CAGCAATCGCAGCTCTTTCGGGAGATTGGGCAGGACCTGGAGCAGTCGCTTTCCAATGGGCAGAGCTTTCACGAACACAT
TAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTATGGTCAGGTCAAGTCCAAGTTGGGTGGCGAGT
TGACAGTTTATGCAGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGTTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.743

99.13

0.632
  comGB/cglB Streptococcus mitis SK321

60.119

97.391

0.586
  comYB Streptococcus mutans UA140

58.944

98.841

0.583
  comYB Streptococcus mutans UA159

58.944

98.841

0.583
  comGB/cglB Streptococcus mitis NCTC 12261

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae Rx1

59.104

97.101

0.574
  comGB/cglB Streptococcus pneumoniae D39

59.104

97.101

0.574
  comGB/cglB Streptococcus pneumoniae R6

59.104

97.101

0.574
  comGB/cglB Streptococcus pneumoniae TIGR4

59.104

97.101

0.574
  comGB Lactococcus lactis subsp. cremoris KW2

50.742

97.681

0.496

Multiple sequence alignment