Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   EQH24_RS10215 Genome accession   NZ_CP035256
Coordinates   1967895..1968161 (-) Length   88 a.a.
NCBI ID   WP_050129046.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901930     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1962895..1973161
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH24_RS10175 (EQH24_10700) rnpA 1962912..1963283 (-) 372 WP_000739244.1 ribonuclease P protein component -
  EQH24_RS11675 - 1963300..1963431 (-) 132 WP_000768904.1 hypothetical protein -
  EQH24_RS10180 (EQH24_10705) - 1963432..1964622 (-) 1191 WP_000167753.1 acetate kinase -
  EQH24_RS10185 (EQH24_10710) comGH 1964673..1965626 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  EQH24_RS10190 (EQH24_10715) - 1965687..1966281 (-) 595 Protein_2013 class I SAM-dependent methyltransferase -
  EQH24_RS10195 (EQH24_10720) comGG/cglG 1966418..1966831 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH24_RS10200 (EQH24_10725) comGF/cglF 1966809..1967270 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH24_RS10205 (EQH24_10730) comGE/cglE 1967233..1967535 (-) 303 WP_256901086.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH24_RS10210 (EQH24_10735) comGD/cglD 1967498..1967902 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH24_RS10215 (EQH24_10740) comGC/cglC 1967895..1968161 (-) 267 WP_050129046.1 competence type IV pilus major pilin ComGC Machinery gene
  EQH24_RS10220 (EQH24_10745) - 1968163..1968420 (-) 258 WP_238101663.1 hypothetical protein -
  EQH24_RS10225 (EQH24_10750) - 1968652..1969608 (-) 957 WP_000350480.1 N-acetylmuramoyl-L-alanine amidase family protein -
  EQH24_RS10230 (EQH24_10755) - 1969612..1969944 (-) 333 WP_001186219.1 phage holin -
  EQH24_RS10235 (EQH24_10760) - 1969948..1970247 (-) 300 WP_001811580.1 hypothetical protein -
  EQH24_RS10240 (EQH24_10765) - 1970256..1970606 (-) 351 WP_000852245.1 hypothetical protein -
  EQH24_RS10245 (EQH24_10770) - 1970609..1970812 (-) 204 WP_001091123.1 hypothetical protein -
  EQH24_RS10250 (EQH24_10775) - 1970793..1970909 (-) 117 WP_001063632.1 hypothetical protein -

Sequence


Protein


Download         Length: 88 a.a.        Molecular weight: 9892.34 Da        Isoelectric Point: 5.8767

>NTDB_id=297010 EQH24_RS10215 WP_050129046.1 1967895..1968161(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1901930]
MLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQAKAYKEYHDKNG
EANRKVND

Nucleotide


Download         Length: 267 bp        

>NTDB_id=297010 EQH24_RS10215 WP_050129046.1 1967895..1968161(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1901930]
ATGTTGGTGGTCTTGCTGATTATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAA
TGACAAAGGAAAAGCAGCTGTTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTA
GCCTAAGCAAGTTAAAAGACGATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGA
GAAGCAAATCGTAAAGTCAATGATTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

95.455

100

0.955

  comGC/cglC Streptococcus pneumoniae D39

95.455

100

0.955

  comGC/cglC Streptococcus pneumoniae R6

95.455

100

0.955

  comGC/cglC Streptococcus pneumoniae TIGR4

94.318

100

0.943

  comGC/cglC Streptococcus mitis SK321

90.541

84.091

0.761

  comGC/cglC Streptococcus mitis NCTC 12261

93.75

72.727

0.682

  comGC Streptococcus gordonii str. Challis substr. CH1

66.667

98.864

0.659

  comGC Streptococcus suis isolate S10

65.278

81.818

0.534

  comGC Streptococcus mutans UA140

60

79.545

0.477

  comGC Streptococcus mutans UA159

60

79.545

0.477

  comGC Lactococcus lactis subsp. cremoris KW2

50.667

85.227

0.432

  comGC Staphylococcus aureus MW2

43.529

96.591

0.42

  comGC Staphylococcus aureus N315

43.529

96.591

0.42