Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Tharo_RS05360 Genome accession   NZ_CP028339
Coordinates   1113393..1114622 (-) Length   409 a.a.
NCBI ID   WP_107220309.1    Uniprot ID   A0A2R4BL08
Organism   Thauera aromatica K172     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1108393..1119622
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Tharo_RS05335 (Tharo_1057) prmC 1108622..1109491 (+) 870 WP_107220304.1 peptide chain release factor N(5)-glutamine methyltransferase -
  Tharo_RS05340 (Tharo_1058) aspS 1109556..1111355 (-) 1800 WP_107220305.1 aspartate--tRNA ligase -
  Tharo_RS05345 (Tharo_1059) - 1111457..1112083 (-) 627 WP_107220306.1 DUF502 domain-containing protein -
  Tharo_RS05350 (Tharo_1060) - 1112133..1112390 (-) 258 WP_107220307.1 zinc ribbon domain-containing protein -
  Tharo_RS05355 (Tharo_1061) pilD 1112538..1113389 (-) 852 WP_107220308.1 A24 family peptidase Machinery gene
  Tharo_RS05360 (Tharo_1062) pilC 1113393..1114622 (-) 1230 WP_107220309.1 type II secretion system F family protein Machinery gene
  Tharo_RS05365 (Tharo_1063) pilB 1114637..1116352 (-) 1716 WP_107220310.1 type IV-A pilus assembly ATPase PilB Machinery gene
  Tharo_RS05370 (Tharo_1064) - 1116441..1117721 (-) 1281 WP_107220311.1 HlyC/CorC family transporter -
  Tharo_RS05375 (Tharo_1065) ccsA 1117861..1118691 (-) 831 WP_107220312.1 cytochrome c biogenesis protein CcsA -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 44223.04 Da        Isoelectric Point: 10.3651

>NTDB_id=284220 Tharo_RS05360 WP_107220309.1 1113393..1114622(-) (pilC) [Thauera aromatica K172]
MATASRAVRGTGPKEDLYSWEGRDKTGKLIRGEMRASGDAMVQAMLRRQGIRVSKVRKQKLSRGRRIGDKEIALFTRQLA
TMMKSGVPLLQAFDIAMKGSGNPALSRLLNEIRNDVETGSSLSQAFAKHPRHFDKLFTNLVAAGEQAGILDSLLDRIATY
KEKILAIKSKIKSALFYPAAVVVVAGLVISVMMLFVIPEFKNVFSSFGADLPAPTLMVIAMSDFFVAYWYLVFGALLAAV
LAIAWSYKRSSAMQIAVDRIVLHLPLVGPIIRKATVARWTRTLSTMFAAGVPLVEALDSVGGASGNHVYLTATRQVQSDV
STGTSLTVAMQNAAVFPAMVVQMVSIGEESGQLDSMLGKVADFFEREVDDAVAGLSQLLEPLIMVFLGTIIGGLVVAMYL
PIFKLGSVV

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=284220 Tharo_RS05360 WP_107220309.1 1113393..1114622(-) (pilC) [Thauera aromatica K172]
ATGGCGACAGCAAGCCGGGCAGTGCGCGGCACGGGCCCGAAGGAAGACCTGTACAGCTGGGAAGGCAGGGACAAGACGGG
CAAGCTGATCCGCGGCGAAATGCGCGCCAGCGGCGACGCCATGGTCCAGGCCATGCTGCGCCGCCAGGGCATCCGGGTGA
GCAAGGTGCGCAAGCAGAAGCTGTCGCGCGGCCGACGCATCGGCGACAAGGAAATCGCCCTGTTCACCCGCCAGCTCGCC
ACCATGATGAAATCCGGTGTGCCCCTGCTCCAGGCCTTCGACATCGCCATGAAAGGGTCGGGCAATCCGGCACTGTCGCG
CCTGCTCAACGAGATCCGCAACGACGTCGAGACCGGCTCCAGCCTGTCCCAGGCATTCGCCAAACACCCCCGGCACTTCG
ACAAGCTGTTCACCAACCTGGTCGCCGCCGGCGAGCAGGCGGGCATCCTCGACAGCCTGCTCGACCGCATCGCCACCTAC
AAGGAAAAGATCCTCGCGATCAAGAGCAAGATCAAGTCGGCCCTGTTCTACCCCGCGGCCGTGGTCGTGGTTGCCGGCCT
GGTGATTTCGGTGATGATGCTGTTCGTGATTCCCGAGTTCAAGAACGTATTCTCCAGCTTCGGCGCCGACCTGCCGGCCC
CCACGCTGATGGTGATCGCGATGTCCGACTTCTTCGTCGCCTACTGGTATTTGGTGTTCGGAGCGCTGCTCGCGGCCGTG
CTCGCGATCGCCTGGAGCTACAAGCGCTCGAGCGCAATGCAGATCGCCGTCGATCGCATCGTGCTGCATCTGCCGCTGGT
CGGCCCGATCATCCGCAAGGCCACCGTGGCCCGCTGGACACGCACCCTGTCGACGATGTTCGCCGCCGGCGTGCCCTTGG
TCGAAGCCCTCGACTCGGTGGGCGGCGCCTCGGGCAATCACGTCTACCTGACCGCGACCCGGCAGGTCCAGAGCGACGTC
AGCACCGGCACCAGCCTTACCGTCGCGATGCAGAACGCAGCGGTGTTCCCGGCCATGGTGGTGCAGATGGTGTCGATCGG
CGAGGAATCCGGCCAGCTCGACTCCATGCTCGGCAAGGTCGCGGATTTTTTCGAGCGGGAAGTCGACGACGCCGTCGCCG
GCCTGTCGCAGTTGCTCGAGCCGCTGATCATGGTCTTCCTCGGCACCATCATCGGCGGCCTGGTGGTCGCGATGTACCTG
CCGATCTTCAAGCTCGGCTCGGTCGTGTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(279-401)

Type II secretion system (T2SS), protein F (T2SSF)

(75-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2R4BL08

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

51.768

96.822

0.501
  pilC Pseudomonas stutzeri DSM 10701

51.378

97.555

0.501
  pilG Neisseria gonorrhoeae MS11

50.126

97.066

0.487
  pilG Neisseria meningitidis 44/76-A

49.874

97.066

0.484
  pilC Acinetobacter baylyi ADP1

47.739

97.311

0.465
  pilC Acinetobacter baumannii D1279779

47.607

97.066

0.462
  pilC Vibrio cholerae strain A1552

42.172

96.822

0.408
  pilC Vibrio campbellii strain DS40M4

39.901

99.267

0.396
  pilC Thermus thermophilus HB27

39.152

98.044

0.384

Multiple sequence alignment