Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   AHA_RS19555 Genome accession   NC_008570
Coordinates   4300208..4301449 (+) Length   413 a.a.
NCBI ID   WP_011707570.1    Uniprot ID   A0KPV8
Organism   Aeromonas hydrophila subsp. hydrophila ATCC 7966     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4295208..4306449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AHA_RS19530 (AHA_3865) ampD 4295525..4296097 (-) 573 WP_011707565.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  AHA_RS19535 (AHA_3866) - 4296245..4296715 (+) 471 WP_024944772.1 TIGR02281 family clan AA aspartic protease -
  AHA_RS19540 (AHA_3867) nadC 4296721..4297578 (+) 858 WP_011707567.1 carboxylating nicotinate-nucleotide diphosphorylase -
  AHA_RS19545 (AHA_3868) tapA 4297901..4298383 (+) 483 WP_011707568.1 type IVa pilus major pilin TapA -
  AHA_RS19550 (AHA_3869) pilB 4298377..4300092 (+) 1716 WP_011707569.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  AHA_RS19555 (AHA_3870) pilC 4300208..4301449 (+) 1242 WP_011707570.1 type II secretion system F family protein Machinery gene
  AHA_RS19560 (AHA_3871) pilD 4301472..4302344 (+) 873 WP_011707571.1 A24 family peptidase Machinery gene
  AHA_RS19565 (AHA_3872) coaE 4302364..4302978 (+) 615 WP_011707572.1 dephospho-CoA kinase -
  AHA_RS19570 (AHA_3873) zapD 4303016..4303738 (+) 723 WP_024945431.1 cell division protein ZapD -
  AHA_RS19575 (AHA_3874) yacG 4303748..4303942 (+) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  AHA_RS19580 (AHA_3875) mutT 4304003..4304416 (-) 414 WP_016352173.1 8-oxo-dGTP diphosphatase MutT -
  AHA_RS19585 (AHA_3876) - 4304425..4305609 (-) 1185 WP_011707575.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45422.58 Da        Isoelectric Point: 9.8637

>NTDB_id=26833 AHA_RS19555 WP_011707570.1 4300208..4301449(+) (pilC) [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQNWWYVIFGGIA
LAIFLYVRAWRASQKVKDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=26833 AHA_RS19555 WP_011707570.1 4300208..4301449(+) (pilC) [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCTTTTCGCTGGAGCGGGGTGAATCGCAAGGGCCA
GAAGGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAACTGCGCAAACAGGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAAAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCGGC
CATGCGCGAGCTCATGGGCCAGATTGCCGCCGATGTGGAGACCGGCACGCCTATGTCCGAAGCGCTGCGCCGTCATCCCC
GTCACTTTGACGATCTCTACTGCGATCTGGTGGAGGCTGGCGAACAGTCCGGCGCCCTAGAGACCATCTACGATCGTATC
GCCACCTATCGCGAGAAATCGGAAGCCCTCAAGTCCAAGATCAAGAAAGCCATGTTCTACCCCACAATGGTCATATTGGT
GGCCATTGTCGTTACCTCCATCCTGCTGCTGTTTGTCATTCCCCAGTTCGAGGACATCTTCAAGAGTTTCGGCGCCGAAC
TGCCCATCTTCACCCAGTTCGTCATCGGCATCTCCCGTTTCATGCAGAACTGGTGGTATGTGATCTTTGGCGGCATAGCG
CTCGCCATCTTTCTCTACGTGCGCGCCTGGCGCGCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCATACTGACCAT
CCCCGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGTTTCGCCCGCACCCTCTCCACCACCTTCTCTGCCGGTA
TTCCACTGGTGGATGCCTTGGTTTCTGCGGCAGGCGCCTCCGGCAACTATGTCTACCGTACTGCCGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGTATGCAGATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAGCCTCTCATCATGGTAGTGCTGGGGGTTCTGGTCGGCGGCATGGTGGTCGCC
ATGTATCTGCCCATCTTCAAACTGGGATCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0KPV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

54

96.852

0.523
  pilC Legionella pneumophila strain ERS1305867

51.358

98.063

0.504
  pilC Acinetobacter baylyi ADP1

52.141

96.126

0.501
  pilC Vibrio cholerae strain A1552

47.739

96.368

0.46
  pilC Vibrio campbellii strain DS40M4

46.348

96.126

0.446
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

37.75

96.852

0.366

Multiple sequence alignment