Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C2U47_RS07395 Genome accession   NZ_CP026226
Coordinates   1581986..1583227 (+) Length   413 a.a.
NCBI ID   WP_010675822.1    Uniprot ID   A0A2L0TT63
Organism   Aeromonas sp. ASNIH7     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1576986..1588227
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2U47_RS07370 (C2U47_07370) ampD 1577421..1577993 (-) 573 WP_103261551.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  C2U47_RS07375 (C2U47_07375) - 1578122..1578592 (+) 471 WP_042015101.1 retropepsin-like aspartic protease -
  C2U47_RS07380 (C2U47_07380) nadC 1578596..1579459 (+) 864 WP_103261552.1 carboxylating nicotinate-nucleotide diphosphorylase -
  C2U47_RS23620 (C2U47_07385) - 1579770..1580144 (+) 375 WP_103261553.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  C2U47_RS07390 (C2U47_07390) pilB 1580152..1581858 (+) 1707 WP_103261554.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  C2U47_RS07395 (C2U47_07395) pilC 1581986..1583227 (+) 1242 WP_010675822.1 type II secretion system F family protein Machinery gene
  C2U47_RS07400 (C2U47_07400) pilD 1583305..1584180 (+) 876 WP_103261555.1 A24 family peptidase Machinery gene
  C2U47_RS07405 (C2U47_07405) coaE 1584199..1584813 (+) 615 WP_043154105.1 dephospho-CoA kinase -
  C2U47_RS07410 (C2U47_07410) zapD 1584851..1585573 (+) 723 WP_010675825.1 cell division protein ZapD -
  C2U47_RS07415 (C2U47_07415) yacG 1585584..1585778 (+) 195 WP_039040499.1 DNA gyrase inhibitor YacG -
  C2U47_RS07420 (C2U47_07420) mutT 1585836..1586240 (-) 405 WP_174218568.1 8-oxo-dGTP diphosphatase MutT -
  C2U47_RS07425 (C2U47_07425) - 1586249..1587433 (-) 1185 WP_103261557.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45435.37 Da        Isoelectric Point: 9.9380

>NTDB_id=267914 C2U47_RS07395 WP_010675822.1 1581986..1583227(+) (pilC) [Aeromonas sp. ASNIH7]
MATLAQKRNAPKKVFSYRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQSQGLFSKGGAKIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
AIYREKNEALKSKIKKAMFYPSMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTRFVIAISRFMQEWWYAIFGGAA
LAVFLYVRAWRKSQKVRDNTDKFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATMAIR
NEVVAGMQINVAMRTVDLFPDMVTQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=267914 C2U47_RS07395 WP_010675822.1 1581986..1583227(+) (pilC) [Aeromonas sp. ASNIH7]
ATGGCCACATTAGCTCAAAAACGCAACGCACCGAAAAAAGTCTTCTCCTACCGCTGGCACGGCGTCAACCGCAAGGGACA
GAAGGTCTCAGGCGAGCTGCAAGCCGACAGCATCACCACCGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
GGGTCAGCAAGCAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTTATCTCCCGC
CAGATCACCACTATGCTCTCCGCCGGCGTGCCTCTGGTGCAGAGTCTTCAGATCATTGCCCGCGGCCACGAGAAAGCGGC
GGTGCGCGAGCTCATCGGCCAGATCGCCGCCGATGTGGAAACGGGCACCCCGCTCTCGGAGGCGTTGCGCCGCCATCCCC
GCCACTTCGACGACCTCTATTGCGATCTGGTCGAGGCCGGGGAGCAATCCGGTGCCCTGGAGACCATCTACGACCGTATC
GCCATCTACCGCGAGAAGAACGAAGCCCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCGTCCATGGTCATTCTGGT
GGCCATCGTCGTCACCTCCATCCTGCTGCTCTTCGTCATTCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCTGCCTTCACCCGGTTCGTCATCGCCATCTCCCGCTTTATGCAGGAGTGGTGGTACGCCATCTTTGGCGGCGCTGCT
CTCGCCGTCTTCCTCTATGTGCGGGCCTGGCGAAAATCCCAGAAAGTCAGGGACAACACGGACAAGTTCATCCTCACCAT
TCCCGTGGTGGGCAACATACTGCACAAGGCGGCCATGGCCCGTTTTGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TCCCGCTGGTGGATGCCCTGGTCTCGGCGGCCGGAGCATCCGGCAACTATGTCTATCGCACTGCGACCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTTTTCCCCGACATGGTGACCCAGATGGT
GATGATCGGTGAGGAATCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATTTTCGAACAGGAGGTGGACGACA
TGGTCGACGGCCTCACCAGCCTGCTCGAACCCATCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTCGTGGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0TT63

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.566

95.884

0.542
  pilC Legionella pneumophila strain ERS1305867

52.099

98.063

0.511
  pilC Acinetobacter baylyi ADP1

50.971

99.758

0.508
  pilC Acinetobacter baumannii D1279779

52.369

97.094

0.508
  pilC Vibrio cholerae strain A1552

47.368

96.61

0.458
  pilC Vibrio campbellii strain DS40M4

45.113

96.61

0.436
  pilG Neisseria meningitidis 44/76-A

41.602

93.705

0.39
  pilG Neisseria gonorrhoeae MS11

41.602

93.705

0.39
  pilC Thermus thermophilus HB27

38.75

96.852

0.375

Multiple sequence alignment