Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C2U40_RS19840 Genome accession   NZ_CP026217
Coordinates   4248712..4249953 (+) Length   413 a.a.
NCBI ID   WP_017409439.1    Uniprot ID   A0AAX0XY15
Organism   Aeromonas sp. ASNIH4     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4243712..4254953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2U40_RS19810 (C2U40_19815) ampD 4244077..4244649 (-) 573 WP_103827107.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  C2U40_RS19815 (C2U40_19820) - 4244796..4245266 (+) 471 WP_024944772.1 retropepsin-like aspartic protease -
  C2U40_RS19820 (C2U40_19825) nadC 4245272..4246129 (+) 858 WP_103827108.1 carboxylating nicotinate-nucleotide diphosphorylase -
  C2U40_RS19830 (C2U40_19835) - 4246452..4246883 (+) 432 WP_041216993.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  C2U40_RS19835 (C2U40_19840) pilB 4246890..4248596 (+) 1707 WP_103827109.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  C2U40_RS19840 (C2U40_19845) pilC 4248712..4249953 (+) 1242 WP_017409439.1 type II secretion system F family protein Machinery gene
  C2U40_RS19845 (C2U40_19850) pilD 4249976..4250848 (+) 873 WP_103827110.1 A24 family peptidase Machinery gene
  C2U40_RS19850 (C2U40_19855) coaE 4250867..4251481 (+) 615 WP_103827111.1 dephospho-CoA kinase -
  C2U40_RS19855 (C2U40_19860) zapD 4251519..4252241 (+) 723 WP_024945431.1 cell division protein ZapD -
  C2U40_RS19860 (C2U40_19865) yacG 4252251..4252445 (+) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  C2U40_RS19865 (C2U40_19870) mutT 4252506..4252919 (-) 414 WP_016352173.1 8-oxo-dGTP diphosphatase MutT -
  C2U40_RS19870 (C2U40_19875) - 4252928..4254112 (-) 1185 WP_103827112.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45408.55 Da        Isoelectric Point: 9.8637

>NTDB_id=267871 C2U40_RS19840 WP_017409439.1 4248712..4249953(+) (pilC) [Aeromonas sp. ASNIH4]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQNWWYVIFGGIA
LAIFLYVRAWRASQKVKDNTDKFVLTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=267871 C2U40_RS19840 WP_017409439.1 4248712..4249953(+) (pilC) [Aeromonas sp. ASNIH4]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTGAATCGCAAGGGCCA
GAAGGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAACAGGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAACCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAAAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCGGC
CATGCGCGAGCTCATGGGCCAGATTGCCGCCGATGTGGAGACCGGCACGCCCATGTCCGAGGCACTGCGCCGCCATCCCC
GTCACTTTGACGATCTCTACTGCGATCTGGTGGAGGCTGGCGAGCAGTCCGGCGCTCTGGAGACCATCTACGATCGTATC
GCCACCTATCGCGAGAAATCGGAAGCCCTCAAGTCCAAGATCAAGAAAGCCATGTTCTACCCCACCATGGTCATCCTGGT
GGCCATTGTCGTTACCTCCATCCTGCTGCTGTTCGTCATTCCCCAGTTCGAAGACATCTTCAAGAGCTTCGGCGCCGAGC
TGCCCATCTTCACCCAATTCGTCATCGGCATCTCCCGTTTCATGCAGAACTGGTGGTATGTGATCTTTGGCGGCATAGCG
CTAGCCATCTTTCTCTACGTGCGCGCCTGGCGCGCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCGTACTGACCAT
CCCCGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGCTTCGCCCGCACCCTCTCCACTACCTTCTCCGCCGGCA
TCCCGCTGGTGGATGCTCTGGTCTCTGCGGCAGGCGCCTCCGGCAACTATGTCTACCGCACCGCTGTCATGGCCATTCGT
AACGAGGTGGTGGCCGGTATGCAGATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
AATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAACCTCTCATCATGGTGGTGCTGGGGGTGCTGGTCGGCGGCATGGTGGTCGCC
ATGTATCTACCCATCTTCAAACTAGGATCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

54

96.852

0.523
  pilC Acinetobacter baylyi ADP1

52.393

96.126

0.504
  pilC Legionella pneumophila strain ERS1305867

51.358

98.063

0.504
  pilC Vibrio cholerae strain A1552

47.739

96.368

0.46
  pilC Vibrio campbellii strain DS40M4

46.348

96.126

0.446
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

37.75

96.852

0.366

Multiple sequence alignment