Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C2U30_RS16955 Genome accession   NZ_CP026122
Coordinates   3600453..3601694 (-) Length   413 a.a.
NCBI ID   WP_010675822.1    Uniprot ID   A0A2L0TT63
Organism   Aeromonas sp. ASNIH5     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3595453..3606694
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2U30_RS16925 (C2U30_16930) - 3596247..3597431 (+) 1185 WP_103244155.1 tetratricopeptide repeat protein -
  C2U30_RS16930 (C2U30_16935) mutT 3597440..3597844 (+) 405 WP_171864957.1 8-oxo-dGTP diphosphatase MutT -
  C2U30_RS16935 (C2U30_16940) yacG 3597902..3598096 (-) 195 WP_039040499.1 DNA gyrase inhibitor YacG -
  C2U30_RS16940 (C2U30_16945) zapD 3598107..3598829 (-) 723 WP_010675825.1 cell division protein ZapD -
  C2U30_RS16945 (C2U30_16950) coaE 3598867..3599481 (-) 615 WP_103244156.1 dephospho-CoA kinase -
  C2U30_RS16950 (C2U30_16955) pilD 3599500..3600375 (-) 876 WP_103244157.1 A24 family peptidase Machinery gene
  C2U30_RS16955 (C2U30_16960) pilC 3600453..3601694 (-) 1242 WP_010675822.1 type II secretion system F family protein Machinery gene
  C2U30_RS16960 (C2U30_16965) pilB 3601822..3603528 (-) 1707 WP_041211787.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  C2U30_RS23110 (C2U30_16970) - 3603528..3603917 (-) 390 WP_080989820.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  C2U30_RS16975 (C2U30_16980) nadC 3604230..3605093 (-) 864 WP_103244158.1 carboxylating nicotinate-nucleotide diphosphorylase -
  C2U30_RS16980 (C2U30_16985) - 3605097..3605567 (-) 471 WP_042015101.1 retropepsin-like aspartic protease -
  C2U30_RS16985 (C2U30_16990) ampD 3605696..3606268 (+) 573 WP_103244159.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45435.37 Da        Isoelectric Point: 9.9380

>NTDB_id=267330 C2U30_RS16955 WP_010675822.1 3600453..3601694(-) (pilC) [Aeromonas sp. ASNIH5]
MATLAQKRNAPKKVFSYRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQSQGLFSKGGAKIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
AIYREKNEALKSKIKKAMFYPSMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTRFVIAISRFMQEWWYAIFGGAA
LAVFLYVRAWRKSQKVRDNTDKFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATMAIR
NEVVAGMQINVAMRTVDLFPDMVTQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=267330 C2U30_RS16955 WP_010675822.1 3600453..3601694(-) (pilC) [Aeromonas sp. ASNIH5]
ATGGCCACATTAGCTCAAAAACGCAACGCACCGAAAAAAGTCTTCTCCTACCGCTGGCACGGCGTCAACCGCAAGGGACA
GAAGGTCTCCGGCGAGCTGCAAGCCGACAGCATCACCACCGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
GGGTCAGCAAGCAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACTACCATGCTCTCCGCCGGCGTGCCTCTGGTGCAGAGTCTTCAGATCATCGCTCGCGGCCACGAGAAAGCGGC
TGTGCGCGAGCTCATCGGCCAGATCGCCGCCGATGTGGAAACAGGCACCCCGCTCTCGGAGGCGTTGCGCCGCCATCCTC
GCCACTTCGACGACCTCTATTGCGACCTGGTCGAAGCCGGGGAGCAATCCGGTGCCCTGGAGACCATCTACGACCGTATC
GCCATCTACCGCGAGAAGAACGAAGCCCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCGTCCATGGTCATTCTGGT
GGCCATCGTCGTCACCTCCATCCTGCTGCTCTTCGTCATTCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCGCCTTTACCCGGTTCGTCATCGCCATCTCCCGCTTTATGCAGGAGTGGTGGTACGCCATCTTTGGCGGCGCTGCT
CTCGCCGTCTTCCTCTATGTGCGGGCCTGGCGAAAATCCCAGAAGGTCAGGGACAACACGGACAAGTTCATCCTCACCAT
TCCCGTGGTGGGCAACATACTGCACAAGGCTGCCATGGCCCGTTTTGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TCCCACTGGTGGATGCCCTGGTCTCAGCGGCCGGAGCATCGGGCAACTATGTCTATCGCACTGCGACCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTTTTCCCCGACATGGTGACCCAGATGGT
GATGATCGGTGAGGAATCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATTTTCGAACAGGAAGTGGACGACA
TGGTCGACGGCCTCACCAGCCTGCTCGAACCCATCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTCGTGGCC
ATGTACCTCCCCATTTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0TT63

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.566

95.884

0.542
  pilC Legionella pneumophila strain ERS1305867

52.099

98.063

0.511
  pilC Acinetobacter baylyi ADP1

50.971

99.758

0.508
  pilC Acinetobacter baumannii D1279779

52.369

97.094

0.508
  pilC Vibrio cholerae strain A1552

47.368

96.61

0.458
  pilC Vibrio campbellii strain DS40M4

45.113

96.61

0.436
  pilG Neisseria meningitidis 44/76-A

41.602

93.705

0.39
  pilG Neisseria gonorrhoeae MS11

41.602

93.705

0.39
  pilC Thermus thermophilus HB27

38.75

96.852

0.375

Multiple sequence alignment