Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   MC60_RS15710 Genome accession   NZ_CP026055
Coordinates   3443734..3444975 (-) Length   413 a.a.
NCBI ID   WP_010675822.1    Uniprot ID   A0A2L0TT63
Organism   Aeromonas caviae strain FDAARGOS_72     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3438734..3449975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MC60_RS15680 (MC60_015680) - 3439528..3440712 (+) 1185 WP_103255171.1 tetratricopeptide repeat protein -
  MC60_RS15685 (MC60_015685) mutT 3440721..3441125 (+) 405 WP_171864957.1 8-oxo-dGTP diphosphatase MutT -
  MC60_RS15690 (MC60_015690) yacG 3441183..3441377 (-) 195 WP_010675826.1 DNA gyrase inhibitor YacG -
  MC60_RS15695 (MC60_015695) zapD 3441388..3442110 (-) 723 WP_010675825.1 cell division protein ZapD -
  MC60_RS15700 (MC60_015700) coaE 3442148..3442762 (-) 615 WP_042864857.1 dephospho-CoA kinase -
  MC60_RS15705 (MC60_015705) pilD 3442781..3443656 (-) 876 WP_042864858.1 prepilin peptidase Machinery gene
  MC60_RS15710 (MC60_015710) pilC 3443734..3444975 (-) 1242 WP_010675822.1 type II secretion system F family protein Machinery gene
  MC60_RS15715 (MC60_015715) pilB 3445103..3446809 (-) 1707 WP_042864859.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  MC60_RS15720 (MC60_015720) tapA 3446813..3447307 (-) 495 WP_041213996.1 type IVa pilus major pilin TapA -
  MC60_RS15725 (MC60_015725) nadC 3447618..3448481 (-) 864 WP_042864860.1 carboxylating nicotinate-nucleotide diphosphorylase -
  MC60_RS15730 (MC60_015730) - 3448485..3448955 (-) 471 WP_042864862.1 TIGR02281 family clan AA aspartic protease -
  MC60_RS15735 (MC60_015735) ampD 3449084..3449656 (+) 573 WP_039040507.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45435.37 Da        Isoelectric Point: 9.9380

>NTDB_id=266179 MC60_RS15710 WP_010675822.1 3443734..3444975(-) (pilC) [Aeromonas caviae strain FDAARGOS_72]
MATLAQKRNAPKKVFSYRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQSQGLFSKGGAKIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
AIYREKNEALKSKIKKAMFYPSMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTRFVIAISRFMQEWWYAIFGGAA
LAVFLYVRAWRKSQKVRDNTDKFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATMAIR
NEVVAGMQINVAMRTVDLFPDMVTQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=266179 MC60_RS15710 WP_010675822.1 3443734..3444975(-) (pilC) [Aeromonas caviae strain FDAARGOS_72]
ATGGCCACATTAGCTCAAAAACGCAACGCACCGAAAAAAGTCTTCTCCTACCGCTGGCACGGCGTCAACCGCAAGGGACA
GAAGGTCTCAGGCGAGCTGCAAGCCGACAGCATCACCACCGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
GGGTCAGCAAGCAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTTATCTCCCGC
CAGATCACCACTATGCTCTCCGCCGGCGTGCCTCTGGTGCAGAGTCTTCAGATCATTGCCCGCGGCCACGAGAAAGCGGC
GGTGCGCGAGCTCATCGGCCAGATCGCCGCCGATGTGGAAACGGGCACCCCGCTCTCGGAGGCGTTGCGCCGCCATCCCC
GCCACTTCGACGACCTCTATTGCGATCTGGTCGAGGCCGGGGAGCAATCCGGTGCCCTGGAGACCATCTACGACCGTATC
GCCATCTACCGCGAGAAGAACGAAGCCCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCGTCCATGGTCATTCTGGT
AGCCATCGTCGTCACCTCCATCCTGCTGCTCTTCGTCATTCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCGCCTTTACCCGGTTCGTCATCGCCATCTCCCGCTTCATGCAGGAGTGGTGGTACGCCATCTTTGGCGGCGCTGCT
CTCGCCGTCTTCCTCTATGTGCGGGCCTGGCGAAAATCTCAGAAGGTCAGGGACAACACGGACAAGTTCATCCTCACCAT
TCCCGTGGTGGGCAACATACTGCACAAGGCGGCCATGGCCCGTTTTGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TCCCGCTGGTGGATGCCCTGGTCTCGGCGGCCGGAGCATCCGGCAACTATGTCTATCGCACTGCGACCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTTTTCCCCGACATGGTGACCCAGATGGT
GATGATCGGTGAGGAATCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATTTTCGAACAGGAGGTGGACGACA
TGGTCGACGGCCTCACCAGCCTGCTCGAACCCATCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTCGTGGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0TT63

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.566

95.884

0.542
  pilC Legionella pneumophila strain ERS1305867

52.099

98.063

0.511
  pilC Acinetobacter baylyi ADP1

50.971

99.758

0.508
  pilC Acinetobacter baumannii D1279779

52.369

97.094

0.508
  pilC Vibrio cholerae strain A1552

47.368

96.61

0.458
  pilC Vibrio campbellii strain DS40M4

45.113

96.61

0.436
  pilG Neisseria meningitidis 44/76-A

41.602

93.705

0.39
  pilG Neisseria gonorrhoeae MS11

41.602

93.705

0.39
  pilC Thermus thermophilus HB27

38.75

96.852

0.375

Multiple sequence alignment