Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   LSEI_RS04400 Genome accession   NC_008526
Coordinates   898619..899860 (+) Length   413 a.a.
NCBI ID   WP_003601723.1    Uniprot ID   A0A0K1KXK2
Organism   Lacticaseibacillus paracasei ATCC 334     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 875550..909170 898619..899860 within 0


Gene organization within MGE regions


Location: 875550..909170
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LSEI_RS04285 (LSEI_0899) - 876256..876891 (-) 636 WP_011674312.1 DsbA family protein -
  LSEI_RS04290 (LSEI_0900) - 876961..877554 (-) 594 WP_003601679.1 CYTH domain-containing protein -
  LSEI_RS04295 (LSEI_0901) - 877748..878419 (+) 672 WP_011674313.1 GTP pyrophosphokinase family protein -
  LSEI_RS04300 (LSEI_0902) - 878421..879218 (+) 798 WP_003564146.1 NAD kinase -
  LSEI_RS04305 (LSEI_0903) - 879218..880120 (+) 903 WP_011674314.1 RluA family pseudouridine synthase -
  LSEI_RS04310 (LSEI_0904) - 880229..881287 (-) 1059 WP_003569478.1 FAD:protein FMN transferase -
  LSEI_RS04315 (LSEI_0905) - 881444..882079 (-) 636 WP_003569480.1 copper homeostasis protein CutC -
  LSEI_RS04320 (LSEI_0906) - 882101..882919 (-) 819 WP_003564150.1 undecaprenyl-diphosphate phosphatase -
  LSEI_RS04325 (LSEI_0907) - 883138..884136 (+) 999 WP_011674315.1 IS30 family transposase -
  LSEI_RS04330 (LSEI_0908) - 884241..885281 (-) 1041 WP_003564151.1 lactonase family protein -
  LSEI_RS04335 (LSEI_0909) - 885553..885930 (+) 378 WP_003564152.1 PTS glucitol/sorbitol transporter subunit IIA -
  LSEI_RS04340 (LSEI_0910) rpsN 886043..886312 (-) 270 WP_003564153.1 30S ribosomal protein S14 -
  LSEI_RS04345 (LSEI_0911) - 886440..887417 (-) 978 WP_032674946.1 GMP reductase -
  LSEI_RS04350 (LSEI_0912) - 887657..888605 (-) 949 Protein_837 magnesium transporter CorA family protein -
  LSEI_RS04355 (LSEI_0913) - 888671..889513 (+) 843 WP_003569501.1 methyltransferase domain-containing protein -
  LSEI_RS04360 (LSEI_0914) trmL 889767..890276 (+) 510 WP_011674316.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
  LSEI_RS04365 (LSEI_0915) - 890403..890813 (+) 411 WP_003564159.1 DUF1149 family protein -
  LSEI_RS04370 (LSEI_0916) - 890986..893307 (+) 2322 WP_011674317.1 FtsK/SpoIIIE family DNA translocase -
  LSEI_RS04375 (LSEI_0917) yfmF 893316..894578 (+) 1263 WP_011674318.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  LSEI_RS04380 (LSEI_0918) yfmH 894575..895867 (+) 1293 WP_011674319.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  LSEI_RS04385 (LSEI_0919) ymfI 895867..896595 (+) 729 WP_003569514.1 elongation factor P 5-aminopentanone reductase -
  LSEI_RS04390 (LSEI_0920) - 896682..897611 (+) 930 WP_011674320.1 helix-turn-helix domain-containing protein -
  LSEI_RS04395 (LSEI_0921) pgsA 897608..898201 (+) 594 WP_003569518.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LSEI_RS04400 (LSEI_0922) cinA 898619..899860 (+) 1242 WP_003601723.1 competence/damage-inducible protein A Machinery gene
  LSEI_RS04405 (LSEI_0923) recA 899917..900978 (+) 1062 WP_011674321.1 recombinase RecA Machinery gene
  LSEI_RS04410 (LSEI_0924) rny 901273..902844 (+) 1572 WP_003657913.1 ribonuclease Y -
  LSEI_RS04415 (LSEI_0925) - 902938..903588 (-) 651 WP_003574282.1 YigZ family protein -
  LSEI_RS04420 (LSEI_0926) - 903616..904878 (+) 1263 WP_011674322.1 DEAD/DEAH box helicase -
  LSEI_RS04425 (LSEI_0927) - 905091..905552 (+) 462 WP_003583965.1 ComF family protein -
  LSEI_RS04430 (LSEI_0928) hpf 905676..906233 (+) 558 WP_003569531.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  LSEI_RS04435 (LSEI_0929) secA 906567..908930 (+) 2364 WP_003578257.1 preprotein translocase subunit SecA -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44298.64 Da        Isoelectric Point: 6.0028

>NTDB_id=26523 LSEI_RS04400 WP_003601723.1 898619..899860(+) (cinA) [Lacticaseibacillus paracasei ATCC 334]
MQAEIIAVGTEILMGQITNTNGAYMAKQLTALGIDSYHQQVVGDNGPRLEEAIKLAESRSNLVILIGGLGPTPDDLTKQT
LAAHLNRKLVEDPDAMAKLQARVKQQQRPMTPNNQLQAMYPEGADILVNRVGLAVGAWIVNGQHTYVLLPGPPKEFVPMV
DHELLPRLAKWSGHAEVMVSRVLRFFGIGESQLVTDLDDLIANQTDPTIATYIKDHEVTVRVTASGATEKDADAKLEPMV
GAIMDRDGQYFYGYGDDNSLAKELVKTLAANDMQITAAESLTAGAFQAALGDVPGVSTYFKGGFVTYSLATKAAFLAIDA
RELAAHGVVSAFTAKAMAEHARRKAAADISVSFTGVAGPDTLEGQPAGTVWIGLARRGQLPEAHVYHFPGGRNDVRQRAV
MTGMMLALRALQA

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=26523 LSEI_RS04400 WP_003601723.1 898619..899860(+) (cinA) [Lacticaseibacillus paracasei ATCC 334]
ATGCAAGCAGAGATTATTGCTGTCGGGACAGAGATCCTGATGGGACAGATTACTAACACAAATGGTGCCTATATGGCTAA
GCAACTGACAGCACTGGGTATTGATAGCTACCATCAACAGGTGGTGGGAGACAACGGCCCGCGACTTGAGGAGGCCATTA
AGTTGGCGGAAAGTCGCAGTAATTTAGTTATTTTGATTGGCGGGTTAGGACCGACACCAGATGATCTGACCAAGCAAACA
TTGGCAGCGCACTTGAACCGCAAATTGGTTGAAGATCCTGACGCTATGGCTAAATTACAGGCGCGCGTCAAGCAACAGCA
GCGGCCAATGACGCCTAATAATCAATTACAGGCCATGTATCCGGAAGGCGCCGATATTTTGGTCAATCGGGTTGGCTTAG
CGGTTGGCGCGTGGATCGTCAATGGGCAGCACACCTATGTTTTATTGCCGGGACCACCGAAGGAATTCGTTCCGATGGTT
GATCATGAACTGTTGCCCCGGCTAGCAAAATGGAGCGGCCACGCGGAAGTTATGGTCAGCCGGGTCTTACGTTTCTTTGG
CATTGGCGAATCGCAACTAGTGACAGATCTGGACGACTTGATTGCCAACCAAACCGATCCGACCATTGCAACTTATATCA
AGGATCATGAGGTGACGGTGCGCGTCACTGCCAGTGGCGCTACCGAAAAAGACGCTGATGCAAAGTTAGAACCAATGGTC
GGTGCCATCATGGATCGTGATGGTCAATATTTTTACGGCTACGGTGACGACAATAGTTTGGCAAAAGAGCTTGTGAAGAC
GCTTGCGGCAAATGATATGCAAATTACTGCAGCTGAGAGTTTGACTGCCGGCGCATTTCAAGCAGCGTTAGGCGATGTGC
CGGGGGTATCCACTTATTTTAAGGGCGGTTTTGTCACTTACTCACTTGCAACAAAGGCCGCTTTTTTGGCAATTGATGCT
CGCGAATTAGCGGCACACGGAGTTGTCAGCGCATTTACAGCCAAGGCGATGGCTGAACATGCTCGGCGTAAGGCAGCGGC
GGATATAAGTGTCAGCTTTACCGGCGTTGCCGGTCCAGACACGCTGGAAGGACAGCCTGCTGGTACGGTTTGGATCGGTT
TAGCGCGGCGCGGCCAGCTGCCTGAAGCACATGTTTACCATTTTCCTGGTGGTCGCAATGATGTCCGGCAGCGTGCTGTG
ATGACTGGTATGATGCTTGCATTAAGGGCACTGCAGGCCTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K1KXK2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis NCTC 12261

51.887

100

0.533
  cinA Streptococcus mitis SK321

51.773

100

0.53
  cinA Streptococcus pneumoniae TIGR4

51.415

100

0.528
  cinA Streptococcus mutans UA159

52.174

100

0.523
  cinA Streptococcus pneumoniae Rx1

50.943

100

0.523
  cinA Streptococcus pneumoniae R6

50.943

100

0.523
  cinA Streptococcus pneumoniae D39

50.708

100

0.521
  cinA Bacillus subtilis subsp. subtilis str. 168

45.012

99.516

0.448
  cinA Streptococcus suis isolate S10

42.063

91.525

0.385

Multiple sequence alignment