Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   CRH08_RS00390 Genome accession   NZ_CP025419
Coordinates   67432..68613 (+) Length   393 a.a.
NCBI ID   WP_024409291.1    Uniprot ID   A0A7Y6VEX9
Organism   Streptococcus suis strain SH0104     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 62432..73613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRH08_RS00375 mutL 64006..65943 (+) 1938 WP_004194473.1 DNA mismatch repair endonuclease MutL -
  CRH08_RS00380 ruvA 65982..66572 (+) 591 WP_004194470.1 Holliday junction branch migration protein RuvA -
  CRH08_RS00385 - 66826..67395 (+) 570 WP_004194469.1 DNA-3-methyladenine glycosylase I -
  CRH08_RS00390 cinA 67432..68613 (+) 1182 WP_024409291.1 competence/damage-inducible protein A Machinery gene
  CRH08_RS00395 recA 68665..69816 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene
  CRH08_RS00400 spx 70052..70450 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  CRH08_RS00405 - 70550..70816 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  CRH08_RS00410 ruvX 70816..71235 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  CRH08_RS00415 - 71247..71567 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  CRH08_RS00420 - 71825..72403 (+) 579 WP_044667815.1 nucleotidyltransferase family protein -
  CRH08_RS00425 comX/sigX 72476..72742 (+) 267 WP_002939335.1 hypothetical protein Regulator
  CRH08_RS00430 rpsJ 73064..73372 (+) 309 WP_013730061.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 43113.09 Da        Isoelectric Point: 4.4531

>NTDB_id=261088 CRH08_RS00390 WP_024409291.1 67432..68613(+) (cinA) [Streptococcus suis strain SH0104]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEVARQRSDLVILCGRLGPTEDDLTKQI
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRILRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=261088 CRH08_RS00390 WP_024409291.1 67432..68613(+) (cinA) [Streptococcus suis strain SH0104]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCGTTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTCTATTTCCACACAGCTGTTGGAGATAATGAACAGAGGCTTCTGTCTGTACTGG
AAGTAGCCCGTCAGCGGAGCGACCTGGTCATTCTCTGTGGAAGATTGGGTCCAACTGAGGATGACTTGACCAAGCAGATC
CTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTATCCTACGTTTTTTTGGCATTGG
TGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATCGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAGGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTAAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7Y6VEX9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

95.674

100

0.957
  cinA Streptococcus mutans UA159

56.448

100

0.59
  cinA Streptococcus pneumoniae R6

55.529

100

0.588
  cinA Streptococcus mitis SK321

55.529

100

0.588
  cinA Streptococcus pneumoniae TIGR4

55.529

100

0.588
  cinA Streptococcus pneumoniae Rx1

55.529

100

0.588
  cinA Streptococcus mitis NCTC 12261

55.288

100

0.585
  cinA Streptococcus pneumoniae D39

55.288

100

0.585
  cinA Bacillus subtilis subsp. subtilis str. 168

40.409

99.491

0.402

Multiple sequence alignment