Detailed information
Bioinformatically predicted
Overview
| Name | comM | Type | Regulator |
| Locus tag | CXP32_RS09895 | Genome accession | NZ_CP025256 |
| Coordinates | 1855744..1856364 (-) | Length | 206 a.a. |
| NCBI ID | WP_000839908.1 | Uniprot ID | A0A0B7M636 |
| Organism | Streptococcus pneumoniae strain Xen35 | ||
| Function | fratricide immunity (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1846996..1867431 | 1855744..1856364 | within | 0 |
Gene organization within MGE regions
Location: 1846996..1867431
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CXP32_RS09840 (CXP32_09840) | - | 1846996..1847355 (-) | 360 | WP_084865738.1 | hypothetical protein | - |
| CXP32_RS09845 (CXP32_09845) | - | 1847401..1847607 (-) | 207 | WP_000366093.1 | hypothetical protein | - |
| CXP32_RS09850 (CXP32_09850) | - | 1847594..1847755 (-) | 162 | WP_000289348.1 | helix-turn-helix transcriptional regulator | - |
| CXP32_RS09855 (CXP32_09855) | lytA | 1848113..1849069 (-) | 957 | WP_000405234.1 | N-acetylmuramoyl-L-alanine amidase LytA | - |
| CXP32_RS09860 (CXP32_09860) | - | 1849445..1850815 (-) | 1371 | WP_001036271.1 | MATE family efflux transporter | - |
| CXP32_RS09870 (CXP32_09870) | recA | 1851121..1852287 (-) | 1167 | WP_001085462.1 | recombinase RecA | Machinery gene |
| CXP32_RS09875 (CXP32_09875) | cinA | 1852342..1853598 (-) | 1257 | WP_000642718.1 | competence/damage-inducible protein A | Machinery gene |
| CXP32_RS09880 (CXP32_09880) | - | 1853683..1854699 (-) | 1017 | WP_000239283.1 | LCP family protein | - |
| CXP32_RS09885 (CXP32_09885) | - | 1854707..1855225 (-) | 519 | WP_000455537.1 | GNAT family N-acetyltransferase | - |
| CXP32_RS09890 (CXP32_09890) | tsaE | 1855215..1855658 (-) | 444 | WP_000288232.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE | - |
| CXP32_RS09895 (CXP32_09895) | comM | 1855744..1856364 (-) | 621 | WP_000839908.1 | hypothetical protein | Regulator |
| CXP32_RS09905 (CXP32_09905) | - | 1856747..1857610 (-) | 864 | WP_001093641.1 | helix-turn-helix transcriptional regulator | - |
| CXP32_RS12630 (CXP32_09910) | - | 1857802..1857972 (+) | 171 | WP_001227862.1 | PhrA family quorum-sensing system peptide | - |
| CXP32_RS09915 (CXP32_09915) | pneA1 | 1858075..1858299 (+) | 225 | WP_000181087.1 | two-peptide bacteriocin subunit PneA1 | - |
| CXP32_RS09920 (CXP32_09920) | pneA2 | 1858306..1858494 (+) | 189 | WP_000786759.1 | two-peptide bacteriocin subunit PneA2 | - |
| CXP32_RS09925 (CXP32_09925) | lanM | 1858610..1861600 (+) | 2991 | WP_000875573.1 | type 2 lanthipeptide synthetase LanM | - |
| CXP32_RS09930 (CXP32_09930) | - | 1861950..1862654 (+) | 705 | WP_001033170.1 | flavodoxin family protein | - |
| CXP32_RS09935 (CXP32_09935) | - | 1862635..1863564 (+) | 930 | WP_000912954.1 | M50 family metallopeptidase | - |
| CXP32_RS09940 (CXP32_09940) | - | 1863561..1865669 (+) | 2109 | WP_000701298.1 | peptidase domain-containing ABC transporter | - |
| CXP32_RS09945 (CXP32_09945) | - | 1865693..1867105 (+) | 1413 | WP_000699968.1 | S8 family serine peptidase | - |
| CXP32_RS12460 | - | 1867159..1867431 (+) | 273 | WP_000939671.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 206 a.a. Molecular weight: 23552.72 Da Isoelectric Point: 10.1254
>NTDB_id=259484 CXP32_RS09895 WP_000839908.1 1855744..1856364(-) (comM) [Streptococcus pneumoniae strain Xen35]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF
Nucleotide
Download Length: 621 bp
>NTDB_id=259484 CXP32_RS09895 WP_000839908.1 1855744..1856364(-) (comM) [Streptococcus pneumoniae strain Xen35]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTGGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTGGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comM | Streptococcus pneumoniae D39 |
100 |
100 |
1 |
| comM | Streptococcus pneumoniae R6 |
100 |
100 |
1 |
| comM | Streptococcus pneumoniae TIGR4 |
100 |
100 |
1 |
| comM | Streptococcus mitis NCTC 12261 |
38.974 |
94.66 |
0.369 |
| comM | Streptococcus mitis SK321 |
38.974 |
94.66 |
0.369 |