Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   CVO91_RS08450 Genome accession   NZ_CP024974
Coordinates   1662117..1662779 (-) Length   220 a.a.
NCBI ID   WP_100664856.1    Uniprot ID   -
Organism   Streptococcus suis strain CZ130302     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1657117..1667779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVO91_RS08445 (CVO91_08445) comEC/celB 1659896..1662133 (-) 2238 WP_100664855.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  CVO91_RS08450 (CVO91_08450) comEA/celA/cilE 1662117..1662779 (-) 663 WP_100664856.1 helix-hairpin-helix domain-containing protein Machinery gene
  CVO91_RS08455 (CVO91_08455) - 1662845..1663591 (-) 747 WP_100664857.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  CVO91_RS08460 (CVO91_08460) - 1663739..1665184 (+) 1446 WP_029185277.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  CVO91_RS08470 (CVO91_08470) - 1665650..1666435 (+) 786 WP_044781467.1 ABC transporter ATP-binding protein -
  CVO91_RS08475 (CVO91_08475) - 1666448..1667377 (+) 930 WP_024382739.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23448.15 Da        Isoelectric Point: 4.0617

>NTDB_id=256935 CVO91_RS08450 WP_100664856.1 1662117..1662779(-) (comEA/celA/cilE) [Streptococcus suis strain CZ130302]
METIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQLEQTSSSSELVEETSAEASEEPSQLVVDVK
GAVVKPGLYTLEAEARVNDAVEAAGGLTSQADPKSVNLAQKLSDEAVVYVASKDENISVVASTTTSSAMSQEEKNTNLVN
LNTATEADLQTISGIGSKRAADIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=256935 CVO91_RS08450 WP_100664856.1 1662117..1662779(-) (comEA/celA/cilE) [Streptococcus suis strain CZ130302]
ATGGAAACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCAGCAGTGGCTGGCTTGCT
AATGGCGACGTTCTTAATCTTCAGTCAACCAGCCAAGTCTGACCAGACAGGACTGACAGATTTTCCACAGCTAGAGCAAA
CTTCTAGCAGCTCTGAGTTGGTCGAGGAAACCAGTGCAGAAGCAAGCGAAGAGCCCAGCCAGCTGGTCGTTGATGTCAAA
GGAGCGGTAGTAAAGCCAGGACTCTACACTTTAGAAGCTGAAGCGCGTGTTAATGACGCAGTTGAAGCAGCTGGCGGCTT
GACCAGTCAGGCAGATCCCAAGTCTGTCAATCTAGCTCAGAAGCTGAGCGACGAGGCGGTCGTCTATGTGGCCAGCAAGG
ACGAAAACATCTCGGTGGTGGCCAGCACGACTACCAGCTCTGCTATGTCCCAAGAAGAAAAAAACACTAATCTAGTTAAT
CTCAACACGGCGACCGAGGCGGACCTACAGACTATTTCGGGCATCGGTTCCAAGCGAGCGGCGGACATTATCGCCTATCG
TGAGGCCAACGGTGGCTTCAAGTCGGTGGATGACCTCAACAATGTTTCGGGCATCGGCGACAAGACCATGGAAAGTATTC
GACCTTATGTCACGGTTGACTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(155-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.673

100

0.5
  comEA/celA/cilE Streptococcus pneumoniae D39

48.673

100

0.5
  comEA/celA/cilE Streptococcus pneumoniae R6

48.673

100

0.5
  comEA/celA/cilE Streptococcus mitis NCTC 12261

48.673

100

0.5
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48

100

0.491
  comEA/celA/cilE Streptococcus mitis SK321

46.429

100

0.473
  comEA Streptococcus thermophilus LMD-9

60.51

71.364

0.432
  comEA Lactococcus lactis subsp. cremoris KW2

38.839

100

0.395
  comEA Bacillus subtilis subsp. subtilis str. 168

39.048

95.455

0.373

Multiple sequence alignment