Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   CVO91_RS08445 Genome accession   NZ_CP024974
Coordinates   1659896..1662133 (-) Length   745 a.a.
NCBI ID   WP_100664855.1    Uniprot ID   -
Organism   Streptococcus suis strain CZ130302     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1654896..1667133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVO91_RS08440 (CVO91_08440) - 1656558..1659725 (-) 3168 WP_100664854.1 ZmpA/ZmpB/ZmpC family metallo-endopeptidase -
  CVO91_RS08445 (CVO91_08445) comEC/celB 1659896..1662133 (-) 2238 WP_100664855.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  CVO91_RS08450 (CVO91_08450) comEA/celA/cilE 1662117..1662779 (-) 663 WP_100664856.1 helix-hairpin-helix domain-containing protein Machinery gene
  CVO91_RS08455 (CVO91_08455) - 1662845..1663591 (-) 747 WP_100664857.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  CVO91_RS08460 (CVO91_08460) - 1663739..1665184 (+) 1446 WP_029185277.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  CVO91_RS08470 (CVO91_08470) - 1665650..1666435 (+) 786 WP_044781467.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 84069.92 Da        Isoelectric Point: 7.1666

>NTDB_id=256934 CVO91_RS08445 WP_100664855.1 1659896..1662133(-) (comEC/celB) [Streptococcus suis strain CZ130302]
MSRLTKLPCQPIHLAILAVAAYFAVHSFSLLTMGLLSLVVVVFWIRQGKTVFLKTLPLLALCGLFFGCQKVQWNRADQSA
SEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQTYFQKLTDLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSSWRRQALVYVKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGILTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPVVKMTWVNGFFVFMEKIIVWVADLGFRPWILGKPSELVLLLLLVSLFLLYDFHRKKNWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVYVVKVGDRLPIFDAYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDNRNIQ
VYRTDQQGAIRFRGWREWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=256934 CVO91_RS08445 WP_100664855.1 1659896..1662133(-) (comEC/celB) [Streptococcus suis strain CZ130302]
ATGTCACGGTTGACTAAGCTCCCCTGCCAGCCCATCCACCTAGCCATCTTAGCGGTGGCGGCATACTTTGCAGTCCACTC
CTTTTCCCTCTTGACAATGGGCCTGTTGAGTCTGGTAGTAGTTGTCTTTTGGATTCGGCAAGGCAAGACAGTTTTTCTCA
AGACGCTGCCGCTTCTAGCCCTGTGCGGTCTCTTTTTCGGATGCCAAAAGGTCCAATGGAATCGGGCAGACCAGTCAGCC
TCAGAGCAAGTCACAACTGTGCAGGTCATTCCAGATACCATTGAAGTCAACGGGGACAGTCTGTCTTTTCGCGGTCGGGC
TGACGGACAAACCTATCAAGTTTTCTACAAATTAGCCAGTCAGGAGGAACAGACTTATTTTCAAAAGCTAACAGATTTGG
TCCAGTTAGAAGTGGAAGCAGAAGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCTTATCTG
AAAACGCAGGGAATTTATCGGACTGTCAAGCTAACGGCGATTAAGAAGATTGTCCCTGTCCAGTCTTGGAATGTTTTTGA
CTGGCTATCAAGCTGGCGGAGGCAAGCCTTGGTCTATGTCAAAACCAATTTTCCAGCTCCTATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAAC
CGTAGATAAGTTACAGATTCCCTTTTCTCTTGTCTATGCGGGCTTGACAGGCTTTTCCGTGTCGGTGGTGCGGTCTTTGG
TTCAAAAAATTCTGGGTAATCTGGGCTTGCGGAAGCTGGATAATTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTTTGCTGACAGCAGGAGGTATCTTGACCTTTACCTATGCTTTTTTGCTGACGGTCTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTTCAGCCCTTGTCTATCCTCTTGACTTTTGTCTTTTCCTTTGTCTTTGATGTCCTGCTCTTGCCAGGTTTGTCGGTC
ATTTTTCTTTTGTCGCCAGTTGTCAAGATGACTTGGGTCAACGGATTTTTTGTCTTTATGGAGAAAATCATTGTCTGGGT
GGCTGATTTGGGTTTTCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TACTTTATGATTTCCACAGGAAGAAAAACTGGCTCCTAGGACTGAGCCTGGTCCTTGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAACGAGGTGACGGTAGTGGACATCGGGCAGGGGGATAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGTCGGGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACCTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGCTTGGTTCTGACCCATACCGATACGGAC
CATGTGGGCGATGTGCTGGAAGTGGCGAAGCAGGTGCAAATTGGTCGGATTGTCGTATCGCCAGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACTCTGAAAAAAATCAATGTTCCTGTCTATGTGGTGAAAGTGGGCGACCGATTGCCGATTTTTGACG
CCTATCTGGAAGTCCTCTATCCAGATGGGACAGGAGACGGTGGCAATAATGACTCTATTGTCCTTTACGGTCGCTTGTTG
GAAACTAATTTTCTTTTTACTGGGGACTTGGAGCAAGGGGAGTTAGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCTGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTCTAGACCATATCGGAGCCAAGATTGCTC
TGGTATCAGCAGGAGAAAATAACCGCTACAAGCACCCTCACCAAGAAACCTTGGAACGATTTGACAATCGGAATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATTCGCTTTCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGGAATGA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Domain of unknown function (DUF4131) (DUF4131)

(30-175)

Competence protein (Competence)

(215-460)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.217

100

0.544
  comEC/celB Streptococcus mitis NCTC 12261

53.154

100

0.532
  comEC/celB Streptococcus pneumoniae TIGR4

52.355

99.732

0.522
  comEC/celB Streptococcus pneumoniae Rx1

52.086

99.732

0.519
  comEC/celB Streptococcus pneumoniae D39

52.086

99.732

0.519
  comEC/celB Streptococcus pneumoniae R6

52.086

99.732

0.519
  comEC Lactococcus lactis subsp. cremoris KW2

48.331

100

0.486

Multiple sequence alignment