Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CVS42_RS18730 Genome accession   NZ_CP024933
Coordinates   4057321..4058562 (+) Length   413 a.a.
NCBI ID   WP_100646865.1    Uniprot ID   -
Organism   Aeromonas veronii strain X12     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4052321..4063562
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVS42_RS18700 (CVS42_18710) ampD 4052626..4053201 (-) 576 WP_100646863.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  CVS42_RS18705 (CVS42_18715) - 4053332..4053802 (+) 471 WP_005336129.1 TIGR02281 family clan AA aspartic protease -
  CVS42_RS18710 (CVS42_18720) nadC 4053806..4054669 (+) 864 WP_040068931.1 carboxylating nicotinate-nucleotide diphosphorylase -
  CVS42_RS22720 (CVS42_18730) - 4054985..4055371 (+) 387 WP_100646864.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  CVS42_RS18725 (CVS42_18735) pilB 4055374..4057080 (+) 1707 WP_005356616.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  CVS42_RS18730 (CVS42_18740) pilC 4057321..4058562 (+) 1242 WP_100646865.1 type II secretion system F family protein Machinery gene
  CVS42_RS18735 (CVS42_18745) pilD 4058624..4059496 (+) 873 WP_100646866.1 A24 family peptidase Machinery gene
  CVS42_RS18740 (CVS42_18750) coaE 4059510..4060124 (+) 615 WP_100646867.1 dephospho-CoA kinase -
  CVS42_RS18745 (CVS42_18755) zapD 4060162..4060884 (+) 723 WP_021231281.1 cell division protein ZapD -
  CVS42_RS18750 (CVS42_18760) yacG 4060894..4061088 (+) 195 WP_100646869.1 DNA gyrase inhibitor YacG -
  CVS42_RS18755 (CVS42_18765) mutT 4061166..4061570 (-) 405 WP_019444787.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45429.52 Da        Isoelectric Point: 9.7221

>NTDB_id=256458 CVS42_RS18730 WP_100646865.1 4057321..4058562(+) (pilC) [Aeromonas veronii strain X12]
MATLSKKNNAPKKVFAFRWHGVNRKGQKVSGELQADSINTVKTELRKQGVNVTKVAKKSQGLFSKGGAKIKPMDIAIVSR
QITTMLSAGVPLVQSLQIIARSHEKASMRELMGQIAADVETGTPMSESLRRHPLYFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPVFTQFVIGISRFMQNWWYVFFGGTA
LGIFLYVRAWRASQKVKDNTDKFVLTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALISAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVIA
MYLPIFKLGDVVG

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=256458 CVS42_RS18730 WP_100646865.1 4057321..4058562(+) (pilC) [Aeromonas veronii strain X12]
ATGGCAACCCTATCGAAAAAGAACAATGCCCCTAAGAAAGTCTTCGCCTTCCGCTGGCACGGGGTAAACCGCAAGGGGCA
GAAGGTCTCCGGCGAGCTGCAGGCCGACAGCATCAACACCGTCAAGACCGAACTGCGCAAGCAGGGGGTCAACGTCACCA
AGGTAGCCAAGAAATCCCAGGGGCTCTTCTCCAAGGGCGGTGCCAAGATCAAACCGATGGATATCGCCATCGTCTCACGC
CAAATAACTACCATGCTCTCCGCCGGTGTACCGCTGGTGCAGAGCCTGCAGATCATCGCCCGCAGTCACGAGAAAGCCTC
GATGCGCGAGCTGATGGGGCAGATTGCCGCCGATGTTGAGACCGGTACTCCCATGTCGGAGTCACTGCGCCGCCATCCCC
TCTACTTTGATGATCTCTATTGCGATCTGGTGGAAGCCGGTGAGCAATCCGGTGCGCTGGAGACCATCTACGACCGTATC
GCCACCTATCGGGAAAAGTCGGAAGCGCTCAAATCGAAGATCAAGAAGGCGATGTTCTACCCCACCATGGTCATTCTGGT
CGCTATCGTGGTGACCTCCATCCTGCTGCTGTTCGTCATTCCGCAGTTTGAGGATATCTTCAAGAGCTTTGGTGCCGAGC
TGCCGGTGTTCACCCAGTTTGTTATCGGCATCTCCCGCTTTATGCAGAACTGGTGGTATGTCTTCTTTGGTGGCACCGCC
CTTGGCATCTTCCTCTATGTGCGGGCCTGGCGGGCCTCCCAGAAGGTGAAAGACAATACCGACAAGTTCGTCCTCACCAT
TCCGGTGGTCGGGATGATCCTGCACAAGGCGGCGATGGCTCGCTTTGCCCGTACTCTGTCAACCACCTTCTCCGCCGGTA
TTCCGCTGGTGGATGCGCTGATTTCGGCGGCTGGGGCCTCGGGTAACTATGTCTATCGCACCGCGGTCATGGCGATCCGC
AACGAGGTGGTGGCCGGTATGCAGATCAACGTGGCGATGCGCACCGTCGATCTCTTCCCCGACATGGTGATTCAGATGGT
GATGATCGGTGAGGAGTCCGGTGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGATGATC
TGGTCGATGGCCTCACCAGCCTGCTGGAACCCCTTATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTTATCGCC
ATGTACCTGCCCATCTTCAAGCTTGGCGACGTGGTAGGCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.576

95.884

0.552
  pilC Acinetobacter baumannii D1279779

53.5

96.852

0.518
  pilC Legionella pneumophila strain ERS1305867

51.232

98.305

0.504
  pilC Acinetobacter baylyi ADP1

52.141

96.126

0.501
  pilC Vibrio cholerae strain A1552

46.633

97.094

0.453
  pilC Vibrio campbellii strain DS40M4

45.545

97.821

0.446
  pilG Neisseria gonorrhoeae MS11

40

98.063

0.392
  pilG Neisseria meningitidis 44/76-A

39.753

98.063

0.39
  pilC Thermus thermophilus HB27

37.75

96.852

0.366

Multiple sequence alignment