Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   DLJ52_RS01290 Genome accession   NZ_CP029559
Coordinates   235695..236444 (+) Length   249 a.a.
NCBI ID   WP_019770842.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NIDR 6715-15     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 230695..241444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DLJ52_RS01270 (DLJ52_01270) - 231109..231654 (+) 546 WP_002962460.1 cysteine hydrolase family protein -
  DLJ52_RS01275 (DLJ52_01275) gltX 231741..233195 (+) 1455 WP_019775465.1 glutamate--tRNA ligase -
  DLJ52_RS01280 (DLJ52_01280) pnuC 233749..234549 (+) 801 WP_002962375.1 nicotinamide riboside transporter PnuC -
  DLJ52_RS01285 (DLJ52_01285) - 234546..235280 (+) 735 WP_019770841.1 NUDIX domain-containing protein -
  DLJ52_RS01290 (DLJ52_01290) comE/blpR 235695..236444 (+) 750 WP_019770842.1 LytTR family DNA-binding domain-containing protein Regulator
  DLJ52_RS01295 (DLJ52_01295) - 237245..238435 (+) 1191 WP_019770844.1 argininosuccinate synthase -
  DLJ52_RS01300 (DLJ52_01300) argH 238884..240263 (+) 1380 WP_109982386.1 argininosuccinate lyase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 28722.86 Da        Isoelectric Point: 5.2334

>NTDB_id=254068 DLJ52_RS01290 WP_019770842.1 235695..236444(+) (comE/blpR) [Streptococcus sobrinus strain NIDR 6715-15]
MNIFILEDNLIQQTRIKTLVAEILREDGVSARQFEVFSKSQNLLDAIVEKGNHQLFLLDIEIKGEEKRGLETAADIRQID
PNAIIVFVTTHSEFAPISFKYKVSALDFIDKTAPDEQFKADLREVIAYTANNMHRSEEVDEVFTFESAQARVQLPFKDIY
YFATSPTPHKVMLITRNERLEFYGSLSEIVEVNSKLFSCHRSFLINLDNISRVDKANLLVYFENGDFCPVSRLKMKALMK
EWEARQGKT

Nucleotide


Download         Length: 750 bp        

>NTDB_id=254068 DLJ52_RS01290 WP_019770842.1 235695..236444(+) (comE/blpR) [Streptococcus sobrinus strain NIDR 6715-15]
ATGAATATATTTATTTTAGAGGATAATTTAATCCAGCAGACGCGGATTAAAACTCTGGTGGCAGAGATTTTGCGGGAGGA
TGGCGTGTCCGCCCGTCAGTTTGAGGTTTTTTCAAAATCGCAAAATTTATTGGATGCGATTGTTGAAAAGGGGAATCATC
AACTGTTTCTTCTGGATATTGAGATTAAGGGAGAAGAAAAGCGGGGATTGGAGACTGCAGCGGACATCCGTCAGATTGAT
CCCAATGCTATTATTGTTTTTGTGACTACCCATTCAGAATTTGCACCAATTAGCTTCAAGTATAAGGTGTCTGCCCTTGA
TTTTATTGATAAGACGGCTCCTGATGAGCAGTTCAAAGCCGATTTGCGGGAGGTCATCGCCTATACGGCCAATAATATGC
ATCGTTCTGAGGAAGTTGATGAAGTCTTTACCTTTGAGTCCGCCCAAGCGCGTGTTCAGCTCCCTTTCAAGGATATTTAC
TACTTTGCGACCTCCCCAACTCCTCACAAGGTTATGTTGATTACGAGGAATGAGCGGCTTGAGTTTTATGGTAGTCTGTC
AGAAATTGTTGAAGTTAATTCCAAACTCTTCTCCTGTCACCGTTCTTTCCTGATAAATTTGGATAATATCAGTCGTGTTG
ATAAGGCCAACTTACTGGTCTATTTTGAAAATGGAGACTTCTGTCCAGTATCGCGTTTAAAGATGAAGGCGCTTATGAAG
GAGTGGGAAGCTAGACAGGGCAAGACCTAA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(152-240)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

49.58

95.582

0.474
  comE/comE1 Streptococcus equinus JB1

43.673

98.394

0.43
  comE/comE2 Streptococcus gordonii strain NCTC7865

40.637

100

0.41
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

40.637

100

0.41
  comE/comE2 Streptococcus equinus JB1

40.741

97.59

0.398
  comE Streptococcus mitis NCTC 12261

37.052

100

0.373
  comE Streptococcus pneumoniae D39

37.052

100

0.373
  comE Streptococcus pneumoniae Rx1

37.052

100

0.373
  comE Streptococcus pneumoniae R6

37.052

100

0.373
  comE Streptococcus pneumoniae TIGR4

37.052

100

0.373
  comE Streptococcus mitis SK321

37.052

100

0.373
  comE Streptococcus infantis strain Atu-4

36.653

100

0.369