Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   DLJ52_RS00890 Genome accession   NZ_CP029559
Coordinates   152831..153778 (+) Length   315 a.a.
NCBI ID   WP_019777327.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NIDR 6715-15     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 147831..158778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DLJ52_RS00875 (DLJ52_00875) - 148710..149072 (-) 363 WP_002959493.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  DLJ52_RS00880 (DLJ52_00880) - 149433..151817 (-) 2385 WP_019785320.1 HAD-IC family P-type ATPase -
  DLJ52_RS00885 (DLJ52_00885) - 152037..152405 (+) 369 WP_019781971.1 DUF1033 family protein -
  DLJ52_RS00890 (DLJ52_00890) comGA/cglA 152831..153778 (+) 948 WP_019777327.1 competence type IV pilus ATPase ComGA Machinery gene
  DLJ52_RS00895 (DLJ52_00895) comGB 153702..154745 (+) 1044 WP_002959504.1 competence type IV pilus assembly protein ComGB Machinery gene
  DLJ52_RS00900 (DLJ52_00900) comGC 154742..155068 (+) 327 WP_019770073.1 competence type IV pilus major pilin ComGC Machinery gene
  DLJ52_RS00905 (DLJ52_00905) comGD 155022..155456 (+) 435 WP_254051091.1 competence type IV pilus minor pilin ComGD Machinery gene
  DLJ52_RS00910 (DLJ52_00910) comGE 155428..155721 (+) 294 WP_002959510.1 competence type IV pilus minor pilin ComGE Machinery gene
  DLJ52_RS00915 (DLJ52_00915) comGF 155705..156142 (+) 438 WP_019781940.1 competence type IV pilus minor pilin ComGF Machinery gene
  DLJ52_RS00920 (DLJ52_00920) comGG 156120..156581 (+) 462 WP_019785527.1 competence type IV pilus minor pilin ComGG Machinery gene
  DLJ52_RS00930 (DLJ52_00930) - 156783..157049 (+) 267 WP_002959516.1 type II toxin-antitoxin system RelE/ParE family toxin -
  DLJ52_RS00935 (DLJ52_00935) - 157036..157311 (+) 276 WP_109982370.1 helix-turn-helix transcriptional regulator -
  DLJ52_RS00940 (DLJ52_00940) comGH 157410..158363 (+) 954 WP_109990554.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 315 a.a.        Molecular weight: 35332.67 Da        Isoelectric Point: 6.3082

>NTDB_id=254058 DLJ52_RS00890 WP_019777327.1 152831..153778(+) (comGA/cglA) [Streptococcus sobrinus strain NIDR 6715-15]
MVEVQELGKELIRQAVEEQAQDIYLLPKPAVYKIYLRFGEKRHLIQTCPPEQAAGLISHFKFLAGMNVGEKRRAQLGACD
YAFADGETAALRLSTVGDYQGRESLVIRLLFDRKRELKFWFDGLNALLPKIIGRGLYLFSGPVGSGKTTLMYELVSRKYP
DSQIITIEDPVEIKQDNMLQLQLNPSIGMTYDHLIKLSLRHRPDVLIIGEIRDRETAQAVIRASLTGIRVFSTVHAKSIP
GVYARILELGVSQDELDNCLAGIAYQRLIGGGGLIDFAQDHFQNHQAECWNEKIDQLLAAGHLTEEEAAAEKIKD

Nucleotide


Download         Length: 948 bp        

>NTDB_id=254058 DLJ52_RS00890 WP_019777327.1 152831..153778(+) (comGA/cglA) [Streptococcus sobrinus strain NIDR 6715-15]
ATGGTTGAAGTGCAGGAGCTGGGAAAGGAATTGATTAGACAGGCAGTTGAGGAGCAGGCTCAGGATATTTATCTTTTGCC
CAAGCCGGCTGTTTATAAGATTTATCTGCGGTTTGGCGAGAAGCGGCACTTGATTCAGACTTGCCCTCCCGAGCAGGCTG
CGGGTCTGATTAGTCACTTTAAATTTCTTGCTGGCATGAATGTTGGTGAGAAGCGACGGGCCCAGCTGGGTGCCTGTGAT
TATGCCTTCGCTGATGGTGAGACAGCGGCCTTGCGTTTATCGACGGTTGGCGACTATCAAGGGCGAGAAAGTCTGGTTAT
TCGCCTGCTCTTTGACAGAAAACGAGAGTTGAAATTTTGGTTTGATGGTCTAAATGCCCTCCTGCCCAAGATTATCGGGC
GAGGCCTCTACCTTTTTTCTGGACCTGTCGGGTCGGGCAAGACGACCCTCATGTATGAACTGGTCAGTCGCAAGTACCCA
GACAGTCAGATTATTACCATTGAGGATCCTGTTGAGATTAAGCAGGATAATATGCTCCAACTCCAGCTTAATCCATCTAT
CGGGATGACCTATGACCATTTGATTAAGCTCTCCCTGCGCCATCGGCCGGATGTTCTAATTATCGGAGAAATTCGCGATA
GGGAGACCGCCCAAGCAGTTATTAGGGCTAGCCTAACAGGGATCCGAGTTTTTTCGACTGTTCATGCCAAGAGTATTCCA
GGGGTCTACGCCCGGATTTTAGAGCTGGGTGTTAGCCAGGATGAGTTAGATAATTGTCTGGCCGGCATTGCCTACCAGCG
TTTAATTGGGGGAGGAGGATTGATTGATTTTGCCCAAGACCATTTTCAAAACCACCAGGCTGAGTGCTGGAATGAAAAAA
TTGACCAACTTCTTGCAGCAGGACATCTCACTGAGGAAGAGGCGGCCGCCGAAAAAATTAAAGACTAG

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(11-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

100

100

1
  comGA Streptococcus mutans UA140

66.026

99.048

0.654
  comGA Streptococcus mutans UA159

66.026

99.048

0.654
  comGA Streptococcus gordonii str. Challis substr. CH1

65.705

99.048

0.651
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

62.581

98.413

0.616
  comGA/cglA/cilD Streptococcus pneumoniae D39

62.581

98.413

0.616
  comGA/cglA/cilD Streptococcus pneumoniae R6

62.581

98.413

0.616
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

62.581

98.413

0.616
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.258

98.413

0.613
  comGA Lactococcus lactis subsp. cremoris KW2

56.129

98.413

0.552