Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   DLJ52_RS00910 Genome accession   NZ_CP029559
Coordinates   155428..155721 (+) Length   97 a.a.
NCBI ID   WP_002959510.1    Uniprot ID   A0ABN5LFY1
Organism   Streptococcus sobrinus strain NIDR 6715-15     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 150428..160721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DLJ52_RS00885 (DLJ52_00885) - 152037..152405 (+) 369 WP_019781971.1 DUF1033 family protein -
  DLJ52_RS00890 (DLJ52_00890) comGA/cglA 152831..153778 (+) 948 WP_019777327.1 competence type IV pilus ATPase ComGA Machinery gene
  DLJ52_RS00895 (DLJ52_00895) comGB 153702..154745 (+) 1044 WP_002959504.1 competence type IV pilus assembly protein ComGB Machinery gene
  DLJ52_RS00900 (DLJ52_00900) comGC 154742..155068 (+) 327 WP_019770073.1 competence type IV pilus major pilin ComGC Machinery gene
  DLJ52_RS00905 (DLJ52_00905) comGD 155022..155456 (+) 435 WP_254051091.1 competence type IV pilus minor pilin ComGD Machinery gene
  DLJ52_RS00910 (DLJ52_00910) comGE 155428..155721 (+) 294 WP_002959510.1 competence type IV pilus minor pilin ComGE Machinery gene
  DLJ52_RS00915 (DLJ52_00915) comGF 155705..156142 (+) 438 WP_019781940.1 competence type IV pilus minor pilin ComGF Machinery gene
  DLJ52_RS00920 (DLJ52_00920) comGG 156120..156581 (+) 462 WP_019785527.1 competence type IV pilus minor pilin ComGG Machinery gene
  DLJ52_RS00930 (DLJ52_00930) - 156783..157049 (+) 267 WP_002959516.1 type II toxin-antitoxin system RelE/ParE family toxin -
  DLJ52_RS00935 (DLJ52_00935) - 157036..157311 (+) 276 WP_109982370.1 helix-turn-helix transcriptional regulator -
  DLJ52_RS00940 (DLJ52_00940) comGH 157410..158363 (+) 954 WP_109990554.1 class I SAM-dependent methyltransferase Machinery gene
  DLJ52_RS00945 (DLJ52_00945) - 158426..159622 (+) 1197 WP_019771614.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10906.87 Da        Isoelectric Point: 10.6169

>NTDB_id=254062 DLJ52_RS00910 WP_002959510.1 155428..155721(+) (comGE) [Streptococcus sobrinus strain NIDR 6715-15]
MVAIKKRKIKAYILLESLIALAVLVTIVTLILTEINRDRQELVASLHRQEVLNLAQMAVQTKQDSLSLNGVTVQVQRTST
SIRVYENGREVLHVAKN

Nucleotide


Download         Length: 294 bp        

>NTDB_id=254062 DLJ52_RS00910 WP_002959510.1 155428..155721(+) (comGE) [Streptococcus sobrinus strain NIDR 6715-15]
GTGGTCGCTATAAAAAAACGGAAAATTAAAGCCTATATTCTCTTAGAAAGCCTGATAGCTCTAGCAGTCTTGGTCACCAT
TGTCACCTTAATCTTGACGGAAATCAACCGAGATCGTCAGGAGCTGGTGGCTAGTCTTCATCGCCAGGAAGTTCTCAACC
TTGCCCAGATGGCAGTTCAGACCAAACAGGACAGTCTCAGTCTGAACGGGGTGACGGTTCAGGTTCAGCGGACTTCGACT
AGCATCAGGGTTTATGAAAATGGCAGGGAGGTTCTCCATGTGGCTAAAAACTAG

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

52.083

98.969

0.515
  comGE Streptococcus mutans UA159

52.083

98.969

0.515
  comGE/cglE Streptococcus pneumoniae D39

42.391

94.845

0.402
  comGE/cglE Streptococcus pneumoniae TIGR4

42.391

94.845

0.402
  comGE/cglE Streptococcus pneumoniae R6

42.391

94.845

0.402
  comGE/cglE Streptococcus pneumoniae Rx1

42.391

94.845

0.402
  comGE Lactococcus lactis subsp. cremoris KW2

39.362

96.907

0.381
  comGE/cglE Streptococcus mitis NCTC 12261

40.217

94.845

0.381
  comGE/cglE Streptococcus mitis SK321

40.217

94.845

0.381

Multiple sequence alignment