Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   CO687_RS01230 Genome accession   NZ_CP023511
Coordinates   255029..255763 (-) Length   244 a.a.
NCBI ID   WP_096754767.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_371     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 250029..260763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO687_RS01200 (CO687_01200) - 250192..250644 (+) 453 WP_048775543.1 DUF3290 family protein -
  CO687_RS01205 (CO687_01205) - 250641..251273 (+) 633 WP_096754763.1 DUF421 domain-containing protein -
  CO687_RS01210 (CO687_01210) - 251455..251658 (+) 204 WP_008808393.1 CsbD family protein -
  CO687_RS01215 (CO687_01215) - 252010..252729 (-) 720 WP_096754764.1 ABC transporter -
  CO687_RS01220 (CO687_01220) - 252722..253402 (-) 681 WP_096754765.1 ABC transporter ATP-binding protein -
  CO687_RS01225 (CO687_01225) - 253688..254953 (-) 1266 WP_138109259.1 GHKL domain-containing protein -
  CO687_RS01230 (CO687_01230) comE/blpR 255029..255763 (-) 735 WP_096754767.1 LytTR family DNA-binding domain-containing protein Regulator
  CO687_RS01240 (CO687_01240) - 256437..256562 (+) 126 Protein_231 integrase -
  CO687_RS10565 - 257163..257330 (-) 168 WP_020992799.1 hypothetical protein -
  CO687_RS01245 (CO687_01245) - 257344..257997 (-) 654 WP_000677415.1 ABC-2 transporter permease -
  CO687_RS01250 (CO687_01250) - 257978..258835 (-) 858 WP_001093359.1 ABC transporter ATP-binding protein -
  CO687_RS01255 (CO687_01255) - 259206..259778 (-) 573 WP_008808384.1 helix-turn-helix transcriptional regulator -
  CO687_RS01260 (CO687_01260) - 259932..260375 (+) 444 WP_046165025.1 hypothetical protein -

Sequence

Protein


Download         Length: 244 a.a.        Molecular weight: 28686.07 Da        Isoelectric Point: 6.3965

>NTDB_id=247938 CO687_RS01230 WP_096754767.1 255029..255763(-) (comE/blpR) [Streptococcus gordonii strain FDAARGOS_371]
MLNIYVLEDEILQQSRMETIIYKVLKDENLKINKFEIFGKPSQLLAEITERGDHQLFFLDIEIKDEEKKGLELAYQIRKL
DPNATIVFVTTHSEFMPLTFRYKVSALDFIDKALGDLHFYERVKSAIEYTLEKNGSTVAHDSFKFETSLSRVQVPFNKIL
YFETSPTVHKVIMHTIDERLEFYAGISEIEKTDNRLYRCHKSFVVNPENISKIDKENRLILFENGESCLVSKTKLKKLKE
RLDF

Nucleotide


Download         Length: 735 bp        

>NTDB_id=247938 CO687_RS01230 WP_096754767.1 255029..255763(-) (comE/blpR) [Streptococcus gordonii strain FDAARGOS_371]
ATGCTAAACATTTATGTTTTGGAAGACGAAATACTACAACAGTCTCGCATGGAGACTATTATTTATAAGGTGCTAAAAGA
TGAAAATTTAAAAATTAATAAGTTTGAGATTTTTGGAAAGCCATCTCAATTATTAGCAGAGATAACTGAGAGAGGGGATC
ATCAGTTATTTTTTTTAGATATTGAGATCAAGGATGAAGAGAAAAAAGGATTGGAGCTTGCTTATCAAATTAGAAAGCTC
GATCCCAATGCAACTATTGTCTTTGTGACTACCCATTCTGAGTTTATGCCATTAACATTTAGATATAAAGTTAGTGCTTT
GGATTTTATTGATAAGGCACTTGGTGATCTTCATTTTTATGAAAGAGTAAAATCAGCGATTGAATATACATTGGAAAAAA
ATGGAAGTACTGTTGCTCATGATTCTTTTAAATTCGAAACATCACTATCTCGTGTCCAAGTTCCATTTAATAAAATTCTT
TATTTTGAAACATCGCCTACTGTGCATAAGGTTATTATGCATACGATAGATGAAAGATTAGAATTTTATGCTGGAATTTC
TGAGATTGAAAAAACGGATAATAGGTTATACAGATGTCACAAGTCGTTTGTCGTAAATCCTGAAAACATTAGTAAGATTG
ATAAGGAAAATAGGCTAATTCTATTTGAAAATGGAGAAAGTTGCTTAGTTTCTAAAACTAAATTAAAGAAACTCAAGGAA
AGGTTAGATTTTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-118)

LytTr DNA-binding domain (LytTR)

(152-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

56.198

99.18

0.557
  comE/comE1 Streptococcus equinus JB1

45.798

97.541

0.447
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

40.891

100

0.414
  comE/comE2 Streptococcus gordonii strain NCTC7865

40.891

100

0.414
  comE Streptococcus pneumoniae D39

38.306

100

0.389
  comE Streptococcus pneumoniae Rx1

38.306

100

0.389
  comE Streptococcus mitis SK321

38.306

100

0.389
  comE Streptococcus mitis NCTC 12261

38.306

100

0.389
  comE Streptococcus pneumoniae R6

38.306

100

0.389
  comE Streptococcus pneumoniae TIGR4

38.306

100

0.389
  comE/comE2 Streptococcus equinus JB1

38.683

99.59

0.385
  comE Streptococcus infantis strain Atu-4

36.694

100

0.373

Multiple sequence alignment