Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC/comC2   Type   Regulator
Locus tag   CO686_RS09125 Genome accession   NZ_CP023507
Coordinates   1862604..1862729 (-) Length   41 a.a.
NCBI ID   WP_000799678.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 1857604..1867729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS09100 (CO686_09100) - 1859732..1860274 (+) 543 WP_000665077.1 TetR-like C-terminal domain-containing protein -
  CO686_RS09115 (CO686_09115) comE 1860515..1861267 (-) 753 WP_000866082.1 competence system response regulator transcription factor ComE Regulator
  CO686_RS09120 (CO686_09120) comD 1861264..1862583 (-) 1320 WP_049550146.1 competence system sensor histidine kinase ComD Regulator
  CO686_RS09125 (CO686_09125) comC/comC2 1862604..1862729 (-) 126 WP_000799678.1 competence-stimulating peptide ComC Regulator
  CO686_RS09135 (CO686_09135) rlmH 1863011..1863490 (-) 480 WP_000694219.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  CO686_RS09140 (CO686_09140) htrA 1863676..1864872 (+) 1197 WP_000681804.1 S1C family serine protease Regulator
  CO686_RS09145 (CO686_09145) spo0J 1864930..1865688 (+) 759 WP_002881154.1 ParB/RepB/Spo0J family partition protein Regulator
  CO686_RS09150 (CO686_09150) dnaA 1865906..1867267 (+) 1362 WP_000660630.1 chromosomal replication initiator protein DnaA -

Sequence


Protein


Download         Length: 41 a.a.        Molecular weight: 4960.73 Da        Isoelectric Point: 10.3052

>NTDB_id=247891 CO686_RS09125 WP_000799678.1 1862604..1862729(-) (comC/comC2) [Streptococcus oralis strain FDAARGOS_367]
MKNTVKLEQFKEVTEAELQEIRGGDWRISETIRNLIFPRRK

Nucleotide


Download         Length: 126 bp        

>NTDB_id=247891 CO686_RS09125 WP_000799678.1 1862604..1862729(-) (comC/comC2) [Streptococcus oralis strain FDAARGOS_367]
ATGAAAAATACAGTAAAGTTGGAACAATTTAAAGAGGTAACAGAGGCAGAATTGCAGGAGATTCGAGGTGGAGATTGGAG
AATTTCAGAAACAATTCGTAATCTTATTTTTCCAAGAAGAAAGTAA

Domains


Predicted by InterproScan.

(1-29)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus pneumoniae A66

56.098

100

0.561

  comC/comC2 Streptococcus pneumoniae TIGR4

56.098

100

0.561

  comC Streptococcus mitis SK321

56.098

100

0.561

  comC/comC1 Streptococcus pneumoniae R6

53.659

100

0.537

  comC/comC1 Streptococcus pneumoniae G54

53.659

100

0.537

  comC/comC1 Streptococcus pneumoniae D39

53.659

100

0.537

  comC/comC1 Streptococcus pneumoniae Rx1

53.659

100

0.537

  comC Streptococcus mitis NCTC 12261

47.5

97.561

0.463

  comC/comC2 Streptococcus gordonii strain NCTC7865

43.243

90.244

0.39

  comC/comC1 Streptococcus gordonii str. Challis substr. CH1

39.474

92.683

0.366


Multiple sequence alignment