Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   CO686_RS09120 Genome accession   NZ_CP023507
Coordinates   1861264..1862583 (-) Length   439 a.a.
NCBI ID   WP_049550146.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1856264..1867583
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS09095 (CO686_09095) - 1856949..1859603 (-) 2655 WP_049550155.1 YhgE/Pip domain-containing protein -
  CO686_RS09100 (CO686_09100) - 1859732..1860274 (+) 543 WP_000665077.1 TetR-like C-terminal domain-containing protein -
  CO686_RS09115 (CO686_09115) comE 1860515..1861267 (-) 753 WP_000866082.1 competence system response regulator transcription factor ComE Regulator
  CO686_RS09120 (CO686_09120) comD 1861264..1862583 (-) 1320 WP_049550146.1 competence system sensor histidine kinase ComD Regulator
  CO686_RS09125 (CO686_09125) comC/comC2 1862604..1862729 (-) 126 WP_000799678.1 competence-stimulating peptide ComC Regulator
  CO686_RS09135 (CO686_09135) rlmH 1863011..1863490 (-) 480 WP_000694219.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  CO686_RS09140 (CO686_09140) htrA 1863676..1864872 (+) 1197 WP_000681804.1 S1C family serine protease Regulator
  CO686_RS09145 (CO686_09145) spo0J 1864930..1865688 (+) 759 WP_002881154.1 ParB/RepB/Spo0J family partition protein Regulator
  CO686_RS09150 (CO686_09150) dnaA 1865906..1867267 (+) 1362 WP_000660630.1 chromosomal replication initiator protein DnaA -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51239.25 Da        Isoelectric Point: 7.0139

>NTDB_id=247890 CO686_RS09120 WP_049550146.1 1861264..1862583(-) (comD) [Streptococcus oralis strain FDAARGOS_367]
MDLFGLGIAIFYFLIISKSYEWICKINRKEQIVFFSYTCISVFILEEIITLVFSNSFALSKFLFPLVVYLYLRKLKKSEK
YKAIFISLLLSLLYHSTHTFISVTLSSIIGDEVVLHYKSTFLLVVLLMTYFSILIIIRYFHLDIKYFDKDYLYPFLKKVI
VAFFGLHILLFISDIVSTTHHLNSFGSILSTIVFICLLLIFFAMNSHKIQIEKEIALKQKKFEQKHLQTYTDEIVELYNE
IRGFRHDYAGMLVSMQMAIDSGDLQEINRVYNEVLVKANQKLRSEKYTYFDLNNIEDSALRSLIAQSIVYARKNDVEFTL
EVKDIITRLSIDLLDLVRIMSILLNNAVEGAADSYLKQMEVAVIKMDFETVIVIQNSCKITMTPSEDLFALGFSTKGRNR
GLGLNNVKEILDKYDNIILETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=247890 CO686_RS09120 WP_049550146.1 1861264..1862583(-) (comD) [Streptococcus oralis strain FDAARGOS_367]
ATGGATTTATTTGGATTAGGGATAGCTATTTTTTATTTTCTCATCATTAGCAAAAGTTATGAATGGATTTGTAAAATAAA
TAGAAAAGAACAAATTGTTTTTTTCTCTTACACATGCATCTCAGTTTTTATACTTGAAGAAATTATTACACTAGTATTTT
CTAATAGTTTTGCTTTGTCTAAATTTTTATTTCCTTTGGTTGTGTACCTTTATTTAAGAAAGTTAAAGAAGTCTGAAAAA
TACAAAGCTATTTTTATCAGTTTACTACTGTCTTTATTATATCACAGTACTCATACTTTTATATCCGTAACCTTATCTTC
TATAATAGGAGATGAAGTAGTATTACACTATAAAAGTACATTCCTTTTAGTAGTATTGTTAATGACTTATTTTTCTATTC
TAATAATAATTCGTTATTTTCATCTGGATATTAAATATTTTGATAAAGATTATCTGTATCCTTTTTTAAAAAAAGTAATA
GTTGCTTTCTTTGGTTTACATATCTTATTGTTTATTTCAGATATAGTAAGTACAACTCATCATTTAAATAGCTTCGGAAG
TATTTTATCAACCATTGTTTTTATTTGCTTGTTATTGATTTTCTTTGCAATGAATTCTCACAAGATTCAAATTGAAAAAG
AGATTGCTCTAAAACAAAAGAAATTTGAACAAAAACATTTACAGACTTATACTGATGAAATTGTGGAGTTGTATAATGAA
ATTCGAGGTTTTCGTCATGATTATGCAGGAATGCTTGTCAGCATGCAAATGGCGATTGACAGTGGAGATTTACAAGAAAT
TAACAGGGTTTACAATGAAGTCCTAGTAAAAGCAAATCAGAAATTGAGGTCAGAAAAATATACTTACTTTGATTTAAATA
ATATAGAAGATTCTGCTTTACGAAGTTTAATTGCTCAATCGATTGTCTATGCACGAAAAAATGATGTAGAGTTTACATTG
GAAGTAAAGGATATCATTACTAGACTGTCAATAGATTTACTTGATCTTGTTCGTATCATGAGCATTTTACTAAACAATGC
CGTTGAAGGTGCTGCAGATAGTTATTTGAAACAAATGGAAGTTGCAGTCATTAAAATGGATTTTGAAACAGTTATAGTTA
TCCAAAATTCATGCAAAATCACTATGACGCCTTCAGAGGATCTATTTGCCTTAGGTTTCTCTACCAAGGGAAGAAATAGA
GGTCTAGGACTTAATAATGTCAAAGAGATTTTAGATAAGTATGACAACATTATCTTAGAAACAGAGATGGAAGACAACAC
ATTTAGACAAATTATTAGATTTAAGAGGGAATTCGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis SK321

75.057

100

0.754
  comD Streptococcus mitis NCTC 12261

74.603

100

0.749
  comD/comD2 Streptococcus pneumoniae TIGR4

73.923

100

0.743
  comD/comD1 Streptococcus pneumoniae R6

73.469

100

0.738
  comD/comD1 Streptococcus pneumoniae Rx1

73.469

100

0.738
  comD/comD1 Streptococcus pneumoniae D39

73.469

100

0.738
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.465

85.194

0.421
  comD/comD2 Streptococcus gordonii strain NCTC7865

48.936

85.649

0.419

Multiple sequence alignment