Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CK627_RS01590 Genome accession   NZ_CP023141
Coordinates   288390..289631 (+) Length   413 a.a.
NCBI ID   WP_005305649.1    Uniprot ID   K1JJY1
Organism   Aeromonas dhakensis strain KN-Mc-6U21     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 283390..294631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CK627_RS01560 (CK627_01560) ampD 283783..284355 (-) 573 WP_095591544.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  CK627_RS01565 (CK627_01565) - 284479..284949 (+) 471 WP_095591545.1 TIGR02281 family clan AA aspartic protease -
  CK627_RS01570 (CK627_01570) nadC 284954..285811 (+) 858 WP_095591546.1 carboxylating nicotinate-nucleotide diphosphorylase -
  CK627_RS01580 (CK627_01580) tapA 286133..286561 (+) 429 WP_041204773.1 type IVa pilus major pilin TapA -
  CK627_RS01585 (CK627_01585) pilB 286568..288274 (+) 1707 WP_024943110.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  CK627_RS01590 (CK627_01590) pilC 288390..289631 (+) 1242 WP_005305649.1 type II secretion system F family protein Machinery gene
  CK627_RS01595 (CK627_01595) pilD 289654..290526 (+) 873 WP_095591547.1 A24 family peptidase Machinery gene
  CK627_RS01600 (CK627_01600) coaE 290546..291160 (+) 615 WP_005305656.1 dephospho-CoA kinase -
  CK627_RS01605 (CK627_01605) zapD 291198..291920 (+) 723 WP_026141277.1 cell division protein ZapD -
  CK627_RS01610 (CK627_01610) yacG 291930..292124 (+) 195 WP_017782442.1 DNA gyrase inhibitor YacG -
  CK627_RS01615 (CK627_01615) mutT 292185..292598 (-) 414 WP_026141640.1 8-oxo-dGTP diphosphatase MutT -
  CK627_RS01620 (CK627_01620) - 292607..293785 (-) 1179 WP_095591548.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45440.57 Da        Isoelectric Point: 9.8734

>NTDB_id=244920 CK627_RS01590 WP_005305649.1 288390..289631(+) (pilC) [Aeromonas dhakensis strain KN-Mc-6U21]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTQFVIGISRFMQNWWYMIFGGVA
LAIFLYVRAWRASQKVRDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALISAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=244920 CK627_RS01590 WP_005305649.1 288390..289631(+) (pilC) [Aeromonas dhakensis strain KN-Mc-6U21]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTGAACCGCAAGGGCCA
GAAGGTCTCAGGCGAGCTGCAGGCCGACAGCATCAATACGGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGACTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATTGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAGAGCCTGCAGATCATCGCTCGCAGCCACGAGAAAGCGGC
CATGCGCGAGCTGATGGGTCAGATAGCCGCCGATGTGGAGACCGGTACCCCCATGTCCGAGGCGCTGCGCCGCCATCCCC
GCCACTTCGATGATCTCTATTGCGACCTGGTCGAGGCGGGCGAGCAGTCCGGCGCCCTGGAGACCATCTACGACCGCATC
GCGACTTATCGCGAAAAGTCCGAAGCGCTCAAATCCAAGATCAAGAAGGCCATGTTCTACCCCACCATGGTCATCTTGGT
CGCCATTGTCGTCACCTCCATTCTGCTGCTGTTCGTCATTCCGCAGTTTGAGGACATCTTCAAGAGCTTCGGCGCCGAAC
TGCCCGCCTTTACCCAGTTCGTCATCGGCATCTCCCGCTTCATGCAGAACTGGTGGTATATGATCTTTGGCGGGGTTGCA
CTCGCCATCTTCCTCTACGTGCGAGCCTGGCGTGCCTCGCAGAAAGTCAGAGACAACACCGACAAGTTCATTCTGACCAT
CCCGGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGCTTCGCCCGCACCCTCTCCACCACCTTTTCTGCCGGTA
TCCCGCTGGTGGATGCCCTGATCTCCGCCGCTGGTGCCTCCGGCAACTATGTCTATCGCACCGCCGTCATGGCCATTCGT
AACGAGGTGGTGGCTGGCATGCAGATCAACGTGGCCATGCGCACCGTCGATCTCTTCCCCGACATGGTGATTCAGATGGT
GATGATTGGCGAGGAGTCAGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAACCTCTCATCATGGTGGTGCTGGGGGTACTGGTCGGCGGCATGGTGGTCGCC
ATGTACCTGCCCATCTTCAAACTGGGGTCGGTCATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K1JJY1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.576

95.884

0.552
  pilC Acinetobacter baumannii D1279779

54.25

96.852

0.525
  pilC Legionella pneumophila strain ERS1305867

51.605

98.063

0.506
  pilC Acinetobacter baylyi ADP1

52.393

96.126

0.504
  pilC Vibrio cholerae strain A1552

47.99

96.368

0.462
  pilC Vibrio campbellii strain DS40M4

47.355

96.126

0.455
  pilG Neisseria meningitidis 44/76-A

40.494

98.063

0.397
  pilG Neisseria gonorrhoeae MS11

40.494

98.063

0.397
  pilC Thermus thermophilus HB27

38

96.852

0.368

Multiple sequence alignment