Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   M6_RS00900 Genome accession   NC_006086
Coordinates   144819..145145 (+) Length   108 a.a.
NCBI ID   WP_002986552.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS10394     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 139819..150145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M6_RS00885 (M6_Spy0133) - 142451..142816 (+) 366 WP_002986560.1 DUF1033 family protein -
  M6_RS00890 (M6_Spy0134) comYA 142909..143847 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  M6_RS00895 (M6_Spy0135) comYB 143783..144817 (+) 1035 WP_011184088.1 competence type IV pilus assembly protein ComGB Machinery gene
  M6_RS00900 (M6_Spy0136) comYC 144819..145145 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  M6_RS00905 (M6_Spy0137) comGD 145120..145548 (+) 429 WP_011184089.1 competence type IV pilus minor pilin ComGD -
  M6_RS00910 (M6_Spy0138) comGE 145505..145789 (+) 285 WP_027968839.1 competence type IV pilus minor pilin ComGE -
  M6_RS00915 (M6_Spy0139) comYF 145782..146216 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  M6_RS00920 (M6_Spy0140) comGG 146200..146526 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  M6_RS00925 (M6_Spy0141) comYH 146624..147577 (+) 954 WP_021340467.1 class I SAM-dependent methyltransferase Machinery gene
  M6_RS00930 (M6_Spy0142) - 147636..148832 (+) 1197 WP_002986533.1 acetate kinase -
  M6_RS00935 (M6_Spy0143) - 149019..149327 (+) 309 WP_011017251.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12376.36 Da        Isoelectric Point: 9.8992

>NTDB_id=23428 M6_RS00900 WP_002986552.1 144819..145145(+) (comYC) [Streptococcus pyogenes MGAS10394]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=23428 M6_RS00900 WP_002986552.1 144819..145145(+) (comYC) [Streptococcus pyogenes MGAS10394]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment