Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | M6_RS00925 | Genome accession | NC_006086 |
| Coordinates | 146624..147577 (+) | Length | 317 a.a. |
| NCBI ID | WP_021340467.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes MGAS10394 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 141624..152577
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M6_RS00885 (M6_Spy0133) | - | 142451..142816 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| M6_RS00890 (M6_Spy0134) | comYA | 142909..143847 (+) | 939 | WP_002986557.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| M6_RS00895 (M6_Spy0135) | comYB | 143783..144817 (+) | 1035 | WP_011184088.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| M6_RS00900 (M6_Spy0136) | comYC | 144819..145145 (+) | 327 | WP_002986552.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| M6_RS00905 (M6_Spy0137) | comGD | 145120..145548 (+) | 429 | WP_011184089.1 | competence type IV pilus minor pilin ComGD | - |
| M6_RS00910 (M6_Spy0138) | comGE | 145505..145789 (+) | 285 | WP_027968839.1 | competence type IV pilus minor pilin ComGE | - |
| M6_RS00915 (M6_Spy0139) | comYF | 145782..146216 (+) | 435 | WP_002986542.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| M6_RS00920 (M6_Spy0140) | comGG | 146200..146526 (+) | 327 | WP_002986539.1 | competence type IV pilus minor pilin ComGG | - |
| M6_RS00925 (M6_Spy0141) | comYH | 146624..147577 (+) | 954 | WP_021340467.1 | class I SAM-dependent methyltransferase | Machinery gene |
| M6_RS00930 (M6_Spy0142) | - | 147636..148832 (+) | 1197 | WP_002986533.1 | acetate kinase | - |
| M6_RS00935 (M6_Spy0143) | - | 149019..149327 (+) | 309 | WP_011017251.1 | hypothetical protein | - |
| M6_RS00940 (M6_Spy0144) | proC | 149410..150180 (-) | 771 | WP_011184092.1 | pyrroline-5-carboxylate reductase | - |
| M6_RS00945 (M6_Spy0145) | pepA | 150228..151295 (-) | 1068 | WP_011184093.1 | glutamyl aminopeptidase | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 35971.05 Da Isoelectric Point: 4.7205
>NTDB_id=23430 M6_RS00925 WP_021340467.1 146624..147577(+) (comYH) [Streptococcus pyogenes MGAS10394]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFVQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFVQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=23430 M6_RS00925 WP_021340467.1 146624..147577(+) (comYH) [Streptococcus pyogenes MGAS10394]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAATTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCCCATTTTGTTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTAATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCTAATGCTAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAATTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCCCATTTTGTTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTAATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCTAATGCTAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
66.456 |
99.685 |
0.662 |
| comYH | Streptococcus mutans UA140 |
66.139 |
99.685 |
0.659 |