Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CCO03_RS15780 Genome accession   NZ_CP021455
Coordinates   3699535..3700752 (+) Length   405 a.a.
NCBI ID   WP_087282585.1    Uniprot ID   A0A1Y0EQT5
Organism   Comamonas serinivorans strain DSM 26136     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3694535..3705752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCO03_RS15760 (CCO03_15760) - 3695047..3695430 (-) 384 WP_236903884.1 TlpA family protein disulfide reductase -
  CCO03_RS15765 (CCO03_15765) - 3695577..3696182 (-) 606 WP_087282580.1 hypothetical protein -
  CCO03_RS15770 (CCO03_15770) mpl 3696262..3697647 (+) 1386 WP_087282582.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase -
  CCO03_RS15775 (CCO03_15775) pilB 3697782..3699515 (+) 1734 WP_236904156.1 type IV-A pilus assembly ATPase PilB Machinery gene
  CCO03_RS15780 (CCO03_15780) pilC 3699535..3700752 (+) 1218 WP_087282585.1 type II secretion system F family protein Machinery gene
  CCO03_RS15785 (CCO03_15785) pilD 3700753..3701622 (+) 870 WP_236903886.1 prepilin peptidase Machinery gene
  CCO03_RS15790 (CCO03_15790) coaE 3701619..3702224 (+) 606 WP_087282587.1 dephospho-CoA kinase -
  CCO03_RS15795 (CCO03_15795) zapD 3702350..3703111 (+) 762 WP_087284808.1 cell division protein ZapD -
  CCO03_RS15800 (CCO03_15800) - 3703115..3703342 (+) 228 WP_087282589.1 DNA gyrase inhibitor YacG -
  CCO03_RS15805 (CCO03_15805) - 3703695..3704168 (-) 474 WP_087282591.1 NUDIX domain-containing protein -
  CCO03_RS15810 (CCO03_15810) - 3704165..3705040 (-) 876 WP_087282593.1 ATP-binding protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44377.21 Da        Isoelectric Point: 9.8619

>NTDB_id=230872 CCO03_RS15780 WP_087282585.1 3699535..3700752(+) (pilC) [Comamonas serinivorans strain DSM 26136]
MATAALRSGSDVLFEWEGKDRHGKIVRGELRAGGQAQVQATLRRQGIVTTKIKKRKMRSGKRIKPRDIAIFTRQLATMMK
AGVPLLQSFDIVGRGNPNPSVARLLNDIRADVETGTSLSSAFRKYPLYFNNLYCNLVEAGEAAGILESILDRLATYMEKT
EAIKSKIKSALMYPIAVIVVAFVVVSIIMIFVIPAFKEVFSNFGADLPAPTLFTIAISEFFVAHWWWMFPLIFAAVFFFM
QAWRRNAKVQLVMDRLLLKLPIFGPLVEKSIVARWTRTLSTMFAAGVPLVESLDSVGGASGNAIYAQATEKIQQEVSTGT
SLTTAMTNVNLFPSIVLQMAAIGEESGSLDHMLGKAADFYEAEVDEAVAGLSSLMEPIIIVVLGVIIGGIVVSMYLPIFQ
LGQVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=230872 CCO03_RS15780 WP_087282585.1 3699535..3700752(+) (pilC) [Comamonas serinivorans strain DSM 26136]
ATGGCCACAGCTGCTTTGCGATCAGGTTCGGATGTGCTGTTCGAATGGGAAGGAAAAGACCGACACGGCAAGATCGTTCG
TGGCGAGCTGAGGGCGGGTGGCCAGGCCCAGGTGCAGGCGACGCTGCGGCGTCAGGGCATCGTCACCACCAAGATCAAAA
AGCGCAAGATGCGCTCGGGCAAGCGCATCAAGCCGCGGGACATCGCCATTTTCACGCGCCAGCTGGCCACCATGATGAAA
GCCGGCGTGCCCCTGCTGCAGTCGTTCGACATCGTGGGCCGAGGCAACCCCAACCCCAGCGTGGCACGGCTGCTCAACGA
CATTCGGGCCGATGTGGAAACCGGCACCTCCTTGTCTTCGGCCTTCCGCAAGTACCCGCTGTACTTCAACAACCTGTATT
GCAACCTTGTGGAAGCCGGTGAGGCTGCCGGCATCCTGGAAAGCATCCTGGACCGCCTGGCCACCTACATGGAAAAGACC
GAGGCGATCAAGTCCAAGATCAAATCGGCCTTGATGTACCCCATCGCCGTGATCGTGGTCGCCTTTGTCGTGGTGTCCAT
CATCATGATCTTCGTGATCCCGGCGTTCAAGGAGGTGTTCTCGAACTTCGGCGCCGACCTCCCGGCGCCGACCTTGTTCA
CCATCGCCATCAGCGAGTTCTTCGTCGCGCACTGGTGGTGGATGTTCCCACTGATCTTTGCCGCCGTTTTCTTCTTCATG
CAGGCCTGGAGACGCAACGCCAAGGTACAGCTCGTCATGGACCGGCTCCTGCTGAAACTGCCGATTTTCGGCCCCCTGGT
CGAGAAGTCGATCGTCGCGCGCTGGACGCGCACGCTGTCCACCATGTTCGCAGCCGGTGTGCCTTTGGTCGAATCGCTCG
ACTCGGTGGGCGGCGCGTCTGGCAATGCCATCTACGCCCAAGCCACCGAGAAGATCCAACAAGAGGTGTCGACGGGAACC
AGCCTCACCACGGCCATGACGAACGTCAACCTGTTCCCCAGCATCGTGCTGCAGATGGCTGCCATCGGCGAAGAATCCGG
CTCGCTCGATCACATGCTGGGCAAGGCGGCCGACTTCTACGAAGCCGAGGTGGACGAAGCCGTGGCCGGCCTGTCCAGCC
TCATGGAGCCCATCATCATCGTCGTGCTCGGCGTCATCATTGGCGGCATCGTGGTGTCCATGTACCTGCCCATCTTCCAA
TTGGGGCAAGTGGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)

Type II secretion system (T2SS), protein F (T2SSF)

(275-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1Y0EQT5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

53.431

100

0.538
  pilC Legionella pneumophila strain ERS1305867

51.768

97.778

0.506
  pilG Neisseria gonorrhoeae MS11

51.899

97.531

0.506
  pilG Neisseria meningitidis 44/76-A

51.646

97.531

0.504
  pilC Acinetobacter baumannii D1279779

51.134

98.025

0.501
  pilC Acinetobacter baylyi ADP1

51.005

98.272

0.501
  pilC Vibrio cholerae strain A1552

41.31

98.025

0.405
  pilC Thermus thermophilus HB27

37.59

100

0.385
  pilC Vibrio campbellii strain DS40M4

38.539

98.025

0.378

Multiple sequence alignment