Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   A6J87_RS02535 Genome accession   NZ_CP020451
Coordinates   511911..512645 (-) Length   244 a.a.
NCBI ID   WP_080611527.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 506911..517645
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS02525 (A6J87_02510) - 509847..510497 (-) 651 WP_080611525.1 DUF6287 domain-containing protein -
  A6J87_RS02530 (A6J87_02515) - 510595..511914 (-) 1320 WP_080611526.1 sensor histidine kinase -
  A6J87_RS02535 (A6J87_02520) comE/blpR 511911..512645 (-) 735 WP_080611527.1 response regulator transcription factor Regulator
  A6J87_RS02540 (A6J87_02525) - 512856..515411 (-) 2556 WP_080611528.1 SH3 domain-containing protein -
  A6J87_RS02545 (A6J87_02530) - 515573..516508 (-) 936 WP_080611529.1 hypothetical protein -

Sequence

Protein


Download         Length: 244 a.a.        Molecular weight: 28501.88 Da        Isoelectric Point: 6.4985

>NTDB_id=223226 A6J87_RS02535 WP_080611527.1 511911..512645(-) (comE/blpR) [Streptococcus salivarius strain FDAARGOS_259]
MLNIYVLEDQFIQQNRIEEVIHTILKKNNIKVGDFEVFDKPNQLLESVTERGSHQLFFLDIQIKDDTKKGLVVAKQIRKN
DPYANIVFFTTHSEYLPLTFQYQLAALDFIDKSLEGEDFQKRVESIILLTCKKIQSQNPEDAFRIENAKTVIQVPFHDIL
YFETSDIVHKVILYTKEEQIEFYGSLSQIEKSDPRLFKCHKSFLINPENIIKLDKSTGTVYFENGGVCYVSKLKLKKLLE
RISL

Nucleotide


Download         Length: 735 bp        

>NTDB_id=223226 A6J87_RS02535 WP_080611527.1 511911..512645(-) (comE/blpR) [Streptococcus salivarius strain FDAARGOS_259]
ATGCTTAACATCTATGTTTTAGAGGATCAATTTATCCAACAAAATCGTATTGAAGAGGTTATTCATACGATTCTTAAGAA
AAATAATATTAAAGTGGGCGACTTTGAGGTTTTTGACAAACCCAATCAACTGTTAGAGTCTGTTACTGAGAGAGGATCTC
ATCAGCTCTTTTTCCTGGACATTCAGATTAAAGACGATACTAAAAAAGGCTTGGTAGTTGCAAAGCAGATTCGCAAGAAC
GACCCCTATGCCAATATTGTTTTCTTCACGACCCATTCAGAGTATCTTCCCTTAACTTTTCAATACCAACTGGCAGCCCT
AGACTTTATTGATAAGTCTTTGGAGGGTGAGGACTTTCAAAAGCGTGTGGAAAGTATTATCTTATTAACCTGCAAAAAGA
TACAGAGTCAGAATCCAGAAGACGCTTTTCGGATTGAGAATGCTAAGACCGTTATTCAGGTTCCTTTTCATGATATCTTG
TACTTTGAGACGTCAGATATTGTTCATAAGGTTATCCTTTATACTAAAGAGGAGCAGATTGAGTTTTATGGCAGTCTCTC
ACAAATCGAAAAGAGTGACCCTAGACTGTTTAAATGCCACAAATCTTTCCTTATCAACCCAGAAAATATCATCAAATTAG
ATAAAAGTACGGGGACAGTCTATTTTGAAAATGGTGGCGTTTGCTATGTTTCGAAGTTGAAACTAAAGAAATTGCTTGAG
AGAATCAGCCTATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(17-123)

LytTr DNA-binding domain (LytTR)

(151-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

51.046

97.951

0.5
  comE/comE1 Streptococcus equinus JB1

48.117

97.951

0.471
  comE/comE2 Streptococcus equinus JB1

42.149

99.18

0.418
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

38.683

99.59

0.385
  comE/comE2 Streptococcus gordonii strain NCTC7865

38.683

99.59

0.385
  comE Streptococcus infantis strain Atu-4

36.929

98.77

0.365
  comE Streptococcus pneumoniae D39

36.515

98.77

0.361
  comE Streptococcus pneumoniae R6

36.515

98.77

0.361
  comE Streptococcus pneumoniae Rx1

36.515

98.77

0.361
  comE Streptococcus mitis SK321

36.515

98.77

0.361
  comE Streptococcus mitis NCTC 12261

36.515

98.77

0.361
  comE Streptococcus pneumoniae TIGR4

36.515

98.77

0.361

Multiple sequence alignment