Detailed information NTG0222858

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: A6J31_RS01310
• Genome accession: NZ_CP020431
• Coordinates: 53111..53845 (+)
• Length: 244 a.a.
• NCBI ID: WP_064520606.1
• Uniprot ID: -
• Organism: Streptococcus sp. FDAARGOS_192
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 48111..58845

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J31_RS01295 (A6J31_01280)	-	48558..51113 (+)	2556	WP_080610290.1	SH3 domain-containing protein	-
A6J31_RS01300 (A6J31_01285)	-	51315..52067 (+)	753	WP_080610291.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	-
A6J31_RS11485 (A6J31_01290)	-	52203..52868 (+)	666	WP_080610292.1	DUF6287 domain-containing protein	-
A6J31_RS01310 (A6J31_01295)	comE/blpR	53111..53845 (+)	735	WP_064520606.1	response regulator transcription factor	Regulator
A6J31_RS01315 (A6J31_01300)	-	53842..55161 (+)	1320	WP_064520607.1	sensor histidine kinase	-
A6J31_RS01320 (A6J31_01305)	-	55259..55825 (+)	567	WP_064520608.1	hypothetical protein	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28606.97 Da
• Isoelectric Point: 6.1646

>NTDB_id=222858 A6J31_RS01310 WP_064520606.1 53111..53845(+) (comE/blpR) [Streptococcus sp. FDAARGOS_192]
MLNIYVLEDHFIQQNRIEEVIHTILKKNNIKVGDFEIFDKPNQLLESVTERGSHQLFFLDIQIKDDTKKGLEVAKQIRKN
DPYANIVFFTTHSEYLPLTFQYQLAALDFIDKSLEEEDFQKRVESIILLTCKKIQSQNPEDAFRIENVKTVIQVPFHDIL
YLETSDIVHKVILYTKEEQIEFYGSLSQIEKSDPRLFKCHKSFLINPENVIKLDKSTGTVYFENGGVCYVSKLKLKKLLE
RISL

Nucleotide

• Length: 735 bp

>NTDB_id=222858 A6J31_RS01310 WP_064520606.1 53111..53845(+) (comE/blpR) [Streptococcus sp. FDAARGOS_192]
ATGCTTAACATCTATGTTTTAGAGGATCATTTTATCCAACAAAATCGTATTGAAGAGGTTATTCATACGATTCTTAAGAA
AAATAACATTAAAGTGGGAGACTTTGAGATTTTTGACAAGCCCAATCAACTGTTAGAGTCTGTTACCGAGAGAGGGTCTC
ATCAGCTCTTTTTCTTGGACATTCAAATTAAAGACGATACTAAAAAAGGTTTGGAGGTGGCTAAGCAGATTCGCAAGAAT
GATCCCTATGCCAATATTGTTTTCTTCACGACTCATTCAGAGTATCTTCCCTTAACTTTTCAATACCAATTGGCTGCTCT
GGACTTTATTGATAAGTCTTTGGAGGAGGAGGACTTTCAAAAGCGTGTGGAAAGTATTATCTTATTAACTTGCAAAAAGA
TACAGAGTCAGAATCCAGAAGATGCTTTTCGGATTGAGAATGTTAAGACCGTTATTCAGGTTCCCTTTCATGATATCTTG
TACCTTGAGACCTCGGATATCGTTCATAAGGTTATCCTTTATACTAAAGAGGAGCAGATTGAGTTTTATGGCAGTCTCTC
TCAAATTGAAAAGAGTGACCCTAGACTGTTTAAATGCCACAAATCTTTCCTTATCAACCCAGAAAATGTCATCAAATTAG
ATAAAAGTACGGGGACAGTCTATTTTGAAAATGGTGGCGTTTGCTATGTTTCAAAGTTGAAACTAAAGAAATTGCTTGAG
AGAATCAGCCTATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (6-123)

• LytTr DNA-binding domain (LytTR) (151-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	50.41	100	0.504
comE/comE1	Streptococcus equinus JB1	47.699	97.951	0.467
comE/comE2	Streptococcus equinus JB1	41.736	99.18	0.414
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.272	99.59	0.381
comE/comE2	Streptococcus gordonii strain NCTC7865	38.272	99.59	0.381
comE	Streptococcus infantis strain Atu-4	36.929	98.77	0.365
comE	Streptococcus pneumoniae D39	36.515	98.77	0.361
comE	Streptococcus pneumoniae R6	36.515	98.77	0.361
comE	Streptococcus pneumoniae Rx1	36.515	98.77	0.361
comE	Streptococcus mitis SK321	36.515	98.77	0.361
comE	Streptococcus mitis NCTC 12261	36.515	98.77	0.361
comE	Streptococcus pneumoniae TIGR4	36.515	98.77	0.361