Detailed information NTG0021236

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: PA0021
• Genome accession: NC_002516
• Coordinates: 22872..23960 (+)
• Length: 362 a.a.
• NCBI ID: NP_248711.1
• Uniprot ID: Q9I7A6
• Organism: Pseudomonas aeruginosa PAO1
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 17872..28960

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PA0017	-	18767..20071 (-)	1305	NP_248707.1	Ribosomal RNA small subunit methyltransferase B	-
PA0018	fmt	20068..21012 (-)	945	NP_248708.1	methionyl-tRNA formyltransferase	-
PA0019	def	21067..21573 (-)	507	NP_248709.1	peptide deformylase	-
PA0020	tsaP	21712..22737 (+)	1026	NP_248710.1	hypothetical protein	Machinery gene
PA0021	dprA	22872..23960 (+)	1089	NP_248711.1	hypothetical protein	Machinery gene
PA0022	-	24001..24558 (+)	558	NP_248712.1	threonylcarbamoyl-AMP synthase	-
PA0023	qor	24568..25545 (-)	978	NP_248713.1	oxygen-dependent quinone oxidoreductase	-
PA0024	hemF	25736..26653 (+)	918	NP_248714.1	coproporphyrinogen III oxidase	-
PA0025	aroE	26711..27535 (+)	825	NP_248715.1	shikimate dehydrogenase	-
PA0026	plcB	27646..28632 (+)	987	NP_248716.1	phospholipase C	-

Sequence

Protein

• Length: 362 a.a.
• Molecular weight: 37719.24 Da
• Isoelectric Point: 7.0742

>NTDB_id=21236 PA0021 NP_248711.1 22872..23960(+) (dprA) [Pseudomonas aeruginosa PAO1]
MKNHSPAELEARLRLHGLPELGPMRFLRLIEAFGSASSALAAPASAWRTLGVPAEAAAARRSPAVREAAGEALRWLEGLR
RHLLMWDDPGYPALLAEVADAPPLLYVEGAPETLERPQLAMVGSRRASPAGLGTARSFARSLAQGGFAITSGLALGIDGA
AHEGALEAGGATVAVLGTGLRRLYPRRHEALARRIVEGGGALVSELPLDSPPLPANFPRRNRIISGLSLGVLVVEASPAS
GSLITARLAAEQGREVYAIPGSIHHPGARGCHQLIRDGALLVESVGHVLEALRGWAQAEPAEAPAQPLPHPLLALLRAAP
YTSEGLAAASGMTLPDVLATLSELELDGRVACEAGTWVHRSG

Nucleotide

• Length: 1089 bp

>NTDB_id=21236 PA0021 NP_248711.1 22872..23960(+) (dprA) [Pseudomonas aeruginosa PAO1]
ATGAAGAACCATTCTCCAGCCGAACTGGAAGCACGGCTGCGCCTGCATGGCCTGCCCGAACTGGGACCCATGCGCTTCCT
GCGCTTGATCGAGGCCTTCGGTTCGGCCTCTTCCGCGCTTGCCGCGCCAGCCAGCGCCTGGCGCACCCTGGGAGTGCCTG
CCGAGGCCGCCGCCGCGCGGCGCAGCCCGGCGGTGCGGGAAGCGGCGGGTGAAGCCCTGCGCTGGCTGGAAGGTCTGCGC
AGGCACCTGCTGATGTGGGACGACCCGGGATACCCGGCACTGCTCGCCGAAGTCGCCGATGCCCCGCCGCTGCTGTACGT
CGAAGGCGCTCCGGAGACTCTGGAACGGCCGCAACTGGCGATGGTCGGCAGCCGCCGCGCCAGCCCCGCCGGGCTGGGCA
CCGCCCGGAGCTTTGCGCGCAGCCTGGCGCAGGGCGGCTTCGCCATCACCAGCGGGCTGGCCCTGGGCATCGATGGCGCC
GCCCACGAGGGCGCGCTGGAGGCTGGCGGCGCGACCGTGGCAGTCCTCGGCACCGGCCTGCGCAGGCTCTATCCGCGGCG
CCACGAGGCGCTGGCGCGGCGCATCGTCGAGGGTGGCGGCGCGCTGGTTTCGGAGCTGCCGCTGGACAGCCCGCCGCTGC
CGGCAAACTTTCCCCGGCGCAACCGCATCATCAGCGGACTCTCGCTGGGTGTGCTGGTGGTCGAGGCAAGTCCCGCCAGC
GGCTCGCTGATCACCGCGCGGCTGGCGGCGGAACAGGGGCGCGAGGTGTACGCCATTCCGGGTTCCATCCACCATCCCGG
CGCACGTGGCTGCCACCAACTGATTCGCGATGGCGCGCTGCTGGTGGAAAGCGTCGGGCACGTGCTCGAAGCACTGCGCG
GCTGGGCGCAGGCGGAGCCAGCGGAAGCGCCGGCGCAGCCCCTGCCCCACCCTTTGCTGGCGCTGCTGCGCGCCGCGCCC
TACACCAGCGAAGGCCTGGCCGCCGCCAGCGGCATGACGCTGCCCGATGTGCTGGCGACGCTCAGCGAACTGGAACTCGA
CGGCCGGGTCGCCTGCGAGGCCGGCACCTGGGTGCATCGCTCCGGCTGA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (81-283)

• DprA winged helix domain (WHD_DprA) (297-355)

3D structure

• AlphaFold DB: Q9I7A6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Vibrio campbellii strain DS40M4	43.514	100	0.445
dprA	Vibrio cholerae strain A1552	43.048	100	0.445
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	43.048	100	0.445
dprA	Legionella pneumophila strain ERS1305867	43.38	98.066	0.425
dprA	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	42.254	98.066	0.414
dprA	Neisseria gonorrhoeae strain FA1090	44.918	84.254	0.378
dprA	Neisseria gonorrhoeae MS11	44.59	84.254	0.376
dprA	Neisseria meningitidis MC58	46.416	80.939	0.376
dprA	Neisseria meningitidis strain C311	46.416	80.939	0.376
dprA	Acinetobacter baumannii D1279779	38.286	96.685	0.37
dprA	Glaesserella parasuis strain SC1401	46.853	79.006	0.37
dprA	Acinetobacter baumannii strain A118	38	96.685	0.367