Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   BMF34_RS00935 Genome accession   NZ_CP017952
Coordinates   145522..145848 (+) Length   108 a.a.
NCBI ID   WP_003098806.1    Uniprot ID   -
Organism   Streptococcus iniae strain 89353     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 140522..150848
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BMF34_RS00920 (BMF34_00910) - 143187..143552 (+) 366 WP_003098799.1 DUF1033 family protein -
  BMF34_RS00925 (BMF34_00915) comYA 143613..144554 (+) 942 WP_003098801.1 competence type IV pilus ATPase ComGA Machinery gene
  BMF34_RS00930 (BMF34_00920) comYB 144505..145521 (+) 1017 WP_003098804.1 competence type IV pilus assembly protein ComGB Machinery gene
  BMF34_RS00935 (BMF34_00925) comGC/cglC 145522..145848 (+) 327 WP_003098806.1 competence type IV pilus major pilin ComGC Machinery gene
  BMF34_RS10575 (BMF34_00930) comGD 145808..146236 (+) 429 WP_003098807.1 competence type IV pilus minor pilin ComGD -
  BMF34_RS00945 (BMF34_00935) comGE 146208..146501 (+) 294 WP_031239176.1 competence type IV pilus minor pilin ComGE -
  BMF34_RS00950 (BMF34_00940) comYF 146461..146910 (+) 450 WP_119773875.1 competence type IV pilus minor pilin ComGF Machinery gene
  BMF34_RS00955 (BMF34_00945) comGG 146900..147253 (+) 354 WP_003098812.1 competence type IV pilus minor pilin ComGG -
  BMF34_RS00960 (BMF34_00950) comYH 147315..148271 (+) 957 WP_003098815.1 class I SAM-dependent methyltransferase Machinery gene
  BMF34_RS00965 (BMF34_00955) - 148328..149524 (+) 1197 WP_003098816.1 acetate kinase -
  BMF34_RS00970 (BMF34_00960) - 149647..149850 (+) 204 WP_003098819.1 helix-turn-helix transcriptional regulator -
  BMF34_RS00975 (BMF34_00965) - 149863..150315 (+) 453 WP_003098820.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12153.19 Da        Isoelectric Point: 10.0312

>NTDB_id=204312 BMF34_RS00935 WP_003098806.1 145522..145848(+) (comGC/cglC) [Streptococcus iniae strain 89353]
MKTKCKQLKESRTKAFTLLEMLIVLLIISVLMLLFIPNLSKQKDKVTDAGNAAVVKIVENQAELYELTEGGKASLAQLQS
KGHITDKQAKAYQDYYAKNSDKHRQVNN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=204312 BMF34_RS00935 WP_003098806.1 145522..145848(+) (comGC/cglC) [Streptococcus iniae strain 89353]
ATGAAAACAAAATGTAAACAACTAAAAGAAAGCCGTACTAAAGCTTTCACACTTCTAGAAATGTTGATTGTTTTGCTAAT
TATTAGTGTTCTTATGCTACTGTTTATTCCGAATTTAAGTAAGCAAAAAGATAAGGTTACAGATGCTGGTAATGCTGCAG
TGGTTAAAATTGTTGAAAATCAGGCGGAACTATATGAATTAACGGAAGGTGGGAAAGCAAGCCTCGCTCAACTCCAATCA
AAAGGTCATATTACAGACAAACAAGCGAAGGCTTATCAGGATTATTATGCCAAAAACAGTGACAAGCATAGACAAGTTAA
CAACTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae TIGR4

59.259

100

0.593
  comGC/cglC Streptococcus pneumoniae D39

59.259

100

0.593
  comGC/cglC Streptococcus pneumoniae R6

59.259

100

0.593
  comGC/cglC Streptococcus pneumoniae Rx1

59.259

100

0.593
  comGC/cglC Streptococcus mitis SK321

63.366

93.519

0.593
  comYC Streptococcus gordonii str. Challis substr. CH1

61.165

95.37

0.583
  comYC Streptococcus mutans UA140

59.223

95.37

0.565
  comYC Streptococcus mutans UA159

59.223

95.37

0.565
  comGC/cglC Streptococcus mitis NCTC 12261

64.835

84.259

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

51.376

100

0.519
  comYC Streptococcus suis isolate S10

60.92

80.556

0.491

Multiple sequence alignment