Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q5W_RS02445 Genome accession   NZ_CP017311
Coordinates   486931..488148 (-) Length   405 a.a.
NCBI ID   WP_009516505.1    Uniprot ID   A0A1L1PB75
Organism   Hydrogenophaga sp. PBC     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 481931..493148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q5W_RS02415 (Q5W_02415) - 483130..484008 (+) 879 WP_009516499.1 ATP-binding protein -
  Q5W_RS02420 (Q5W_02420) - 484005..484454 (+) 450 WP_009516500.1 NUDIX domain-containing protein -
  Q5W_RS02425 (Q5W_02425) - 484468..484665 (-) 198 WP_009516501.1 DNA gyrase inhibitor YacG -
  Q5W_RS02430 (Q5W_02430) zapD 484670..485425 (-) 756 WP_009516502.1 cell division protein ZapD -
  Q5W_RS25590 (Q5W_02435) coaE 485469..486077 (-) 609 WP_009516503.1 dephospho-CoA kinase -
  Q5W_RS02440 (Q5W_02440) pilD 486074..486931 (-) 858 WP_009516504.1 A24 family peptidase Machinery gene
  Q5W_RS02445 (Q5W_02445) pilC 486931..488148 (-) 1218 WP_009516505.1 type II secretion system F family protein Machinery gene
  Q5W_RS02450 (Q5W_02450) pilB 488183..489913 (-) 1731 WP_035620178.1 type IV-A pilus assembly ATPase PilB Machinery gene
  Q5W_RS02460 (Q5W_02460) - 490194..491123 (-) 930 WP_138820106.1 polyprenyl synthetase family protein -
  Q5W_RS02465 (Q5W_02465) rplU 491398..491709 (+) 312 WP_009516508.1 50S ribosomal protein L21 -
  Q5W_RS02470 (Q5W_02470) rpmA 491721..491978 (+) 258 WP_009516509.1 50S ribosomal protein L27 -
  Q5W_RS02475 (Q5W_02475) obgE 492052..493122 (+) 1071 WP_009516510.1 GTPase ObgE -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44418.08 Da        Isoelectric Point: 9.1369

>NTDB_id=197568 Q5W_RS02445 WP_009516505.1 486931..488148(-) (pilC) [Hydrogenophaga sp. PBC]
MATVASKSVKDFVFEWEGKDRNGKAVRGETRAQGENQVTATLRRQGIIPVKIKKRRTSSGKRIKPKDIAIFTRQLATMMK
AGVPLLQSFDIVGRGNPNPNVTRLLNDIRADVETGTSLSAAFRKHPMYFDSLYCNLIEAGEAAGILEDLLDRLATYMEKT
EALKSKIKSALMYPTAVIIVAFVVVAIIMIFVIPSFKEVFTSFGADLPAPTLFVIGMSEFFVQYWWLIFGGLGGGFYFFM
QAWKRNEKVQRFMDRLLLKLPIFGELIEKSVVARWTRTLATMFGAGVPLVEALDSVGGASGNSVYAIATEKIQQEVSTGT
SLTAAMTNVNIFPSMVLQMCAIGEESGSIDHMLGKAADFYEAEVDDMVAGISSLMEPIIIVVLGTVIGGIVVSMYLPIFK
LGQVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=197568 Q5W_RS02445 WP_009516505.1 486931..488148(-) (pilC) [Hydrogenophaga sp. PBC]
ATGGCCACCGTCGCAAGCAAGAGCGTCAAGGACTTCGTGTTCGAATGGGAGGGCAAGGACCGCAACGGCAAGGCGGTGCG
CGGCGAGACGCGGGCGCAAGGCGAGAACCAGGTCACCGCCACGCTGCGTCGGCAGGGCATCATCCCTGTCAAGATCAAGA
AGCGGCGCACCTCCTCCGGCAAGCGGATCAAGCCGAAGGACATCGCCATCTTCACGCGCCAGCTGGCCACGATGATGAAG
GCGGGCGTGCCCTTGCTGCAGTCCTTCGACATCGTGGGTCGCGGCAACCCCAACCCAAACGTCACGCGTCTGCTCAACGA
CATCCGCGCCGACGTCGAAACCGGTACCTCACTGAGTGCGGCCTTCCGCAAGCACCCGATGTACTTCGACAGCCTCTACT
GCAACCTGATCGAGGCGGGTGAGGCGGCCGGTATCCTGGAAGATCTGCTCGACCGCCTCGCCACCTACATGGAGAAGACC
GAGGCGCTGAAGTCGAAGATCAAGTCCGCCCTGATGTACCCGACGGCGGTGATCATCGTGGCTTTCGTGGTGGTGGCCAT
CATCATGATCTTCGTGATCCCCTCCTTCAAGGAGGTGTTCACCTCGTTCGGCGCCGACCTGCCTGCACCTACGCTGTTCG
TGATCGGCATGAGCGAGTTCTTCGTTCAGTATTGGTGGCTGATCTTCGGTGGCCTCGGTGGCGGCTTCTACTTCTTCATG
CAGGCCTGGAAGCGCAATGAAAAAGTCCAGCGCTTCATGGACCGCCTGTTGCTCAAGCTGCCCATCTTCGGCGAACTGAT
CGAGAAGTCGGTGGTCGCGCGCTGGACTCGCACGCTGGCCACAATGTTCGGCGCCGGCGTTCCGCTGGTCGAGGCGCTCG
ATTCCGTGGGGGGCGCCTCGGGCAACTCGGTGTACGCCATCGCCACCGAAAAGATCCAGCAGGAAGTCTCCACGGGCACC
AGCCTGACGGCCGCGATGACCAACGTGAACATCTTTCCGTCCATGGTGCTGCAGATGTGCGCGATCGGCGAAGAGTCGGG
ATCGATCGATCACATGCTGGGCAAGGCAGCCGACTTCTATGAGGCCGAGGTGGACGACATGGTGGCTGGCATCTCCAGTC
TGATGGAGCCGATCATCATCGTGGTGCTGGGCACGGTCATCGGCGGCATCGTCGTCTCGATGTACCTGCCCATCTTCAAG
CTCGGTCAGGTGGTTTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(275-397)

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L1PB75

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

54.815

100

0.548
  pilG Neisseria gonorrhoeae MS11

52

98.765

0.514
  pilG Neisseria meningitidis 44/76-A

51.75

98.765

0.511
  pilC Acinetobacter baylyi ADP1

50.503

98.272

0.496
  pilC Legionella pneumophila strain ERS1305867

49.497

98.272

0.486
  pilC Acinetobacter baumannii D1279779

48.866

98.025

0.479
  pilC Vibrio cholerae strain A1552

41.562

98.025

0.407
  pilC Vibrio campbellii strain DS40M4

40.25

98.765

0.398
  pilC Thermus thermophilus HB27

37.845

98.519

0.373

Multiple sequence alignment