Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   BFP66_RS00665 Genome accession   NZ_CP017142
Coordinates   99524..100474 (+) Length   316 a.a.
NCBI ID   WP_024417411.1    Uniprot ID   -
Organism   Streptococcus suis strain GZ0565     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 94524..105474
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFP66_RS00655 (BFP66_00655) - 98088..98453 (+) 366 WP_024417409.1 DUF1033 family protein -
  BFP66_RS00660 (BFP66_00660) - 98488..99438 (-) 951 WP_024417410.1 S66 peptidase family protein -
  BFP66_RS00665 (BFP66_00665) comYA 99524..100474 (+) 951 WP_024417411.1 competence type IV pilus ATPase ComGA Machinery gene
  BFP66_RS00670 (BFP66_00670) comYB 100386..101423 (+) 1038 WP_255195823.1 competence type IV pilus assembly protein ComGB Machinery gene
  BFP66_RS00675 (BFP66_00675) comYC 101425..101706 (+) 282 WP_009909092.1 competence type IV pilus major pilin ComGC Machinery gene
  BFP66_RS00680 (BFP66_00680) comGD 101687..102094 (+) 408 WP_024387070.1 competence type IV pilus minor pilin ComGD -
  BFP66_RS00685 (BFP66_00685) comYE 102066..102359 (+) 294 WP_024390433.1 competence type IV pilus minor pilin ComGE Machinery gene
  BFP66_RS00690 (BFP66_00690) comGF/cglF 102346..102780 (+) 435 WP_063725150.1 competence type IV pilus minor pilin ComGF Machinery gene
  BFP66_RS00695 (BFP66_00695) comGG 102758..103168 (+) 411 WP_009909099.1 competence type IV pilus minor pilin ComGG -
  BFP66_RS00700 (BFP66_00700) comYH 103225..104178 (+) 954 WP_024409299.1 class I SAM-dependent methyltransferase Machinery gene
  BFP66_RS00705 (BFP66_00705) - 104228..105415 (+) 1188 WP_014637319.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35407.25 Da        Isoelectric Point: 5.9423

>NTDB_id=195935 BFP66_RS00665 WP_024417411.1 99524..100474(+) (comYA) [Streptococcus suis strain GZ0565]
MIQEKSRKLIEKAVADRVSDIYLVPRGESYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=195935 BFP66_RS00665 WP_024417411.1 99524..100474(+) (comYA) [Streptococcus suis strain GZ0565]
ATGATTCAAGAAAAATCAAGAAAGTTGATTGAAAAGGCAGTGGCGGATAGGGTCAGTGACATTTATCTGGTTCCTCGCGG
GGAAAGCTATCAAGTTTATCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTCTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ATCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACAGGAGCTACCGTTTTCTCAACGGTTCATGCAAGGTCTATTTCGGGTGTCTAT
GCTCGTATGTTGGAATTGGGTGTCAGTCCTGAGGAGTTAAACAATGCCCTTCAAGGTATTGCCTATCAACGTTTAATCGG
GGGAGGAGGTGTGGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTAGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.387

98.101

0.671
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.161

98.101

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

53.628

100

0.538
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

87.658

0.364

Multiple sequence alignment