Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   FORC55_RS02465 Genome accession   NZ_CP016987
Coordinates   493077..494303 (-) Length   408 a.a.
NCBI ID   WP_000648506.1    Uniprot ID   A0A0E3W4T9
Organism   Vibrio cholerae strain FORC_055 isolate MFDS     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 488077..499303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FORC55_RS02440 (FORC55_0445) parC 488078..490363 (+) 2286 WP_000102515.1 DNA topoisomerase IV subunit A -
  FORC55_RS02445 (FORC55_0446) yacG 490412..490609 (-) 198 WP_000162865.1 DNA gyrase inhibitor YacG -
  FORC55_RS02450 (FORC55_0447) zapD 490767..491507 (-) 741 WP_000207194.1 cell division protein ZapD -
  FORC55_RS02455 (FORC55_0448) coaE 491539..492147 (-) 609 WP_000011549.1 dephospho-CoA kinase -
  FORC55_RS02460 (FORC55_0449) pilD 492144..493019 (-) 876 WP_000418750.1 prepilin peptidase Machinery gene
  FORC55_RS02465 (FORC55_0450) pilC 493077..494303 (-) 1227 WP_000648506.1 type II secretion system F family protein Machinery gene
  FORC55_RS02470 (FORC55_0451) pilB 494346..496034 (-) 1689 WP_096070333.1 type IV-A pilus assembly ATPase PilB Machinery gene
  FORC55_RS02475 (FORC55_0452) pilA 496046..496483 (-) 438 WP_096070334.1 pilin Machinery gene
  FORC55_RS02480 (FORC55_0453) nadC 496728..497618 (-) 891 WP_000665275.1 carboxylating nicotinate-nucleotide diphosphorylase -
  FORC55_RS02490 (FORC55_0454) ampD 497920..498465 (+) 546 WP_084998538.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  FORC55_RS02495 (FORC55_0455) fldB 498596..499114 (-) 519 WP_084988580.1 flavodoxin FldB -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45090.38 Da        Isoelectric Point: 10.3424

>NTDB_id=194309 FORC55_RS02465 WP_000648506.1 493077..494303(-) (pilC) [Vibrio cholerae strain FORC_055 isolate MFDS]
MKATQTLPLKNYRWKGINSNGKKVSGQMLAISEIEVRDKLKDQHIQIKKLKKGSVSLLARLTHRVKGKDITILTRQLATM
LTTGVPIVQALKLVGDNHRKAEMKSILAQITKSVEAGTPLSKAMRTASAHFDTLYVDLVETGEMSGNLPEVFERLATYRE
KSEQLRAKVIKALIYPSMVVLVALGVSYLMLTMVIPEFESMFKGFGAELPWFTQQVLKLSHWVQAYSLWAFIAIAAAIFG
LKALRKNSFQIRLKTSRLGLKFPIIGNVLAKASIAKFSRTLATSFAAGIPILASLKTTAKTSGNVHFETAINEVYRDTAA
GMPMYIAMRNTDAFPEMVLQMVMIGEESGQLDDMLNKVATIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=194309 FORC55_RS02465 WP_000648506.1 493077..494303(-) (pilC) [Vibrio cholerae strain FORC_055 isolate MFDS]
ATGAAAGCGACCCAAACCTTACCTCTGAAAAATTATCGCTGGAAAGGCATCAACAGCAACGGCAAAAAAGTTTCCGGCCA
GATGCTCGCCATCTCCGAAATCGAGGTGCGCGATAAGCTCAAAGATCAGCATATTCAGATCAAAAAACTCAAAAAAGGCA
GTGTCTCTTTATTGGCGCGCCTAACCCATCGCGTGAAAGGCAAAGACATCACGATTTTGACTCGGCAGTTGGCGACCATG
CTCACCACGGGCGTACCGATTGTGCAAGCCCTCAAGTTGGTGGGCGATAATCACCGTAAAGCTGAGATGAAATCGATTCT
GGCGCAAATCACCAAAAGCGTGGAAGCGGGCACGCCACTTTCCAAGGCGATGCGCACCGCCAGCGCCCATTTTGATACCT
TGTATGTCGATTTAGTGGAAACCGGAGAGATGTCCGGTAACTTACCTGAAGTGTTTGAGCGTTTGGCCACCTACCGCGAG
AAAAGCGAGCAACTACGCGCCAAGGTGATTAAAGCGCTCATCTACCCGAGTATGGTGGTATTGGTCGCGCTCGGGGTATC
CTACTTAATGCTCACCATGGTCATCCCAGAATTTGAAAGCATGTTTAAAGGCTTTGGTGCCGAGCTGCCTTGGTTTACGC
AGCAAGTGCTGAAACTCTCACACTGGGTGCAGGCTTACAGTTTATGGGCATTTATCGCCATCGCAGCAGCCATTTTTGGC
TTGAAAGCGCTGCGTAAAAACTCTTTCCAGATCCGTTTAAAAACCAGCCGCTTAGGGCTGAAATTTCCGATTATTGGCAA
TGTGCTCGCTAAGGCTTCCATCGCCAAATTCAGCCGCACTCTCGCCACCAGCTTTGCTGCGGGGATCCCAATTCTAGCCA
GTTTAAAAACCACCGCCAAAACCTCCGGCAATGTGCACTTTGAAACCGCGATTAATGAGGTGTACCGCGATACTGCTGCG
GGGATGCCGATGTACATTGCCATGCGCAATACCGACGCTTTTCCCGAAATGGTGCTGCAAATGGTGATGATCGGTGAAGA
GTCTGGACAATTAGATGACATGCTCAACAAGGTCGCGACCATCTATGAATTTGAAGTCGATAACACAGTCGATAACTTGG
GCAAGATTCTTGAGCCACTGATCATCGTGTTTCTTGGGACGGTCGTGGGCGGCTTAGTGGTGGCGATGTACTTACCTATC
TTTAACTTAATGAGTGTATTGGGTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E3W4T9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

99.51

100

0.995
  pilC Vibrio campbellii strain DS40M4

74

98.039

0.725
  pilC Acinetobacter baumannii D1279779

42.647

100

0.426
  pilC Acinetobacter baylyi ADP1

42.015

99.755

0.419
  pilC Legionella pneumophila strain ERS1305867

42.211

97.549

0.412
  pilC Pseudomonas stutzeri DSM 10701

42.172

97.059

0.409
  pilG Neisseria gonorrhoeae MS11

41.045

98.529

0.404
  pilG Neisseria meningitidis 44/76-A

40.547

98.529

0.4

Multiple sequence alignment