Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   S101444_RS20770 Genome accession   NZ_CP021498
Coordinates   3928574..3929776 (-) Length   400 a.a.
NCBI ID   WP_015250812.1    Uniprot ID   A0ABU0V6N7
Organism   Bacillus subtilis subsp. subtilis strain SRCM101444     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3923574..3934776
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  S101444_RS20740 (S101444_04126) - 3924055..3925008 (-) 954 WP_014481469.1 sporulation-delaying protein SdpB family protein -
  S101444_RS20745 (S101444_04127) - 3924993..3925547 (-) 555 WP_015715050.1 SdpA family antimicrobial peptide system protein -
  S101444_RS20750 (S101444_04128) - 3925731..3926366 (-) 636 WP_014481470.1 SdpI family protein -
  S101444_RS20755 (S101444_04129) - 3926366..3926650 (-) 285 WP_015715052.1 autorepressor SdpR family transcription factor -
  S101444_RS20760 (S101444_04130) rocR 3926877..3928262 (+) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  S101444_RS20765 - 3928244..3928396 (-) 153 Protein_4052 ATP-binding protein -
  S101444_RS21395 - 3928424..3928553 (-) 130 Protein_4053 hypothetical protein -
  S101444_RS20770 (S101444_04131) htrA 3928574..3929776 (-) 1203 WP_015250812.1 serine protease HtrC Regulator
  S101444_RS20775 (S101444_04132) vicX 3929858..3930652 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  S101444_RS20780 (S101444_04133) walI 3930674..3931516 (-) 843 WP_046161072.1 WalRK two-component regulatory system regulator WalI -
  S101444_RS20785 (S101444_04134) walH 3931503..3932870 (-) 1368 WP_046161103.1 WalRK two-component regulatory system regulator WalH -
  S101444_RS20790 (S101444_04135) walK 3932860..3934695 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.5340

>NTDB_id=193286 S101444_RS20770 WP_015250812.1 3928574..3929776(-) (htrA) [Bacillus subtilis subsp. subtilis strain SRCM101444]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=193286 S101444_RS20770 WP_015250812.1 3928574..3929776(-) (htrA) [Bacillus subtilis subsp. subtilis strain SRCM101444]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCAAG
CCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTAGATACGGGCG
CTTTAGATCAGCAGCAGAACAATAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATCGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGAAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(196-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378

Multiple sequence alignment