Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   TK34_RS02395 Genome accession   NZ_CP016380
Coordinates   511749..512990 (-) Length   413 a.a.
NCBI ID   WP_017409439.1    Uniprot ID   A0AAX0XY15
Organism   Aeromonas hydrophila strain AHNIH1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 506749..517990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TK34_RS02365 (TK34_02340) mutT 507740..508153 (+) 414 WP_187172441.1 8-oxo-dGTP diphosphatase MutT -
  TK34_RS02370 (TK34_02345) - 508185..509147 (-) 963 WP_065475368.1 IS1595 family transposase -
  TK34_RS02375 (TK34_02350) yacG 509256..509450 (-) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  TK34_RS02380 (TK34_02355) zapD 509460..510182 (-) 723 WP_065475370.1 cell division protein ZapD -
  TK34_RS02385 (TK34_02360) coaE 510220..510834 (-) 615 WP_065475372.1 dephospho-CoA kinase -
  TK34_RS02390 (TK34_02365) pilD 510854..511726 (-) 873 WP_065475375.1 prepilin peptidase Machinery gene
  TK34_RS02395 (TK34_02370) pilC 511749..512990 (-) 1242 WP_017409439.1 type II secretion system F family protein Machinery gene
  TK34_RS02400 (TK34_02375) pilB 513106..514812 (-) 1707 WP_029302067.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  TK34_RS22920 (TK34_02380) tapA 514816..515244 (-) 429 WP_081304776.1 type IVa pilus major pilin TapA -
  TK34_RS02410 (TK34_02390) nadC 515567..516424 (-) 858 WP_065475376.1 carboxylating nicotinate-nucleotide diphosphorylase -
  TK34_RS02415 (TK34_02395) - 516430..516900 (-) 471 WP_024944772.1 retropepsin-like aspartic protease family protein -
  TK34_RS02420 (TK34_02400) ampD 517048..517620 (+) 573 WP_065475378.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45408.55 Da        Isoelectric Point: 9.8637

>NTDB_id=187628 TK34_RS02395 WP_017409439.1 511749..512990(-) (pilC) [Aeromonas hydrophila strain AHNIH1]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQNWWYVIFGGIA
LAIFLYVRAWRASQKVKDNTDKFVLTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=187628 TK34_RS02395 WP_017409439.1 511749..512990(-) (pilC) [Aeromonas hydrophila strain AHNIH1]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTGAATCGCAAGGGCCA
GAAGGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAGCAAGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAAAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCGGC
CATGCGCGAGCTCATGGGCCAGATTGCCGCCGATGTGGAGACCGGCACGCCCATGTCCGAGGCACTGCGCCGCCATCCCC
GCCACTTTGACGATCTTTATTGCGATCTGGTGGAGGCTGGCGAGCAGTCCGGCGCTCTGGAGACCATCTACGATCGCATC
GCCACCTATCGCGAGAAATCGGAAGCACTCAAGTCCAAGATCAAGAAAGCCATGTTCTACCCCACCATGGTCATCCTGGT
GGCCATTGTCGTTACCTCCATCCTGCTGCTGTTTGTCATTCCCCAGTTCGAGGACATCTTCAAGAGTTTCGGCGCCGAGC
TGCCCATCTTCACCCAGTTCGTCATCGGCATCTCCCGTTTCATGCAGAACTGGTGGTACGTGATCTTTGGCGGGATAGCG
CTCGCCATCTTTCTCTACGTGCGCGCCTGGCGCGCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCGTACTGACCAT
CCCCGTAGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGCTTCGCCCGCACCCTCTCCACTACCTTTTCCGCCGGTA
TCCCGCTGGTGGATGCCTTGGTCTCTGCGGCAGGTGCCTCCGGCAACTATGTCTACCGCACTGCCGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTGGCCATGCGCACCGTTGATCTGTTCCCGGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAGCCTCTCATCATGGTGGTGCTGGGGGTTCTGGTCGGCGGCATGGTGGTCGCC
ATGTATCTGCCCATCTTCAAACTGGGATCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

54

96.852

0.523
  pilC Acinetobacter baylyi ADP1

52.393

96.126

0.504
  pilC Legionella pneumophila strain ERS1305867

51.358

98.063

0.504
  pilC Vibrio cholerae strain A1552

47.739

96.368

0.46
  pilC Vibrio campbellii strain DS40M4

46.348

96.126

0.446
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

37.75

96.852

0.366

Multiple sequence alignment