Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A8C75_RS05335 Genome accession   NZ_CP015839
Coordinates   1217144..1218367 (-) Length   407 a.a.
NCBI ID   WP_067379142.1    Uniprot ID   A0A1A9EVP8
Organism   Marinobacterium aestuarii strain ST58-10     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1212144..1223367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A8C75_RS05310 (A8C75_05310) argJ 1213013..1214227 (+) 1215 WP_067379127.1 bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ -
  A8C75_RS05315 (A8C75_05315) - 1214320..1215273 (+) 954 WP_067379130.1 Nudix family hydrolase -
  A8C75_RS05320 (A8C75_05320) yacG 1215286..1215528 (-) 243 WP_067379133.1 DNA gyrase inhibitor YacG -
  A8C75_RS05325 (A8C75_05325) coaE 1215525..1216133 (-) 609 WP_067379136.1 dephospho-CoA kinase -
  A8C75_RS05330 (A8C75_05330) pilD 1216172..1217050 (-) 879 WP_067379139.1 prepilin peptidase Machinery gene
  A8C75_RS05335 (A8C75_05335) pilC 1217144..1218367 (-) 1224 WP_067379142.1 type II secretion system F family protein Machinery gene
  A8C75_RS05340 (A8C75_05340) pilB 1218392..1220101 (-) 1710 WP_067379145.1 type IV-A pilus assembly ATPase PilB Machinery gene
  A8C75_RS05345 (A8C75_05345) - 1220435..1220950 (+) 516 WP_157890226.1 pilin -
  A8C75_RS05350 (A8C75_05350) - 1221271..1221615 (+) 345 WP_067379148.1 hypothetical protein -
  A8C75_RS05355 (A8C75_05355) nadC 1221840..1222679 (-) 840 WP_067379151.1 carboxylating nicotinate-nucleotide diphosphorylase -
  A8C75_RS05360 (A8C75_05360) ampD 1222773..1223357 (+) 585 WP_067379154.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 44451.37 Da        Isoelectric Point: 10.1528

>NTDB_id=182390 A8C75_RS05335 WP_067379142.1 1217144..1218367(-) (pilC) [Marinobacterium aestuarii strain ST58-10]
MATKQVKLQTFVWQGRDKSGNVTKGKLDAANVATARAQLRRQGITPKKVGKESISIFSNRSKAIKPLDIAFFTRQMATML
KSGVPLLQSLEIVAGGSEKDKMKKMLYDIRNDVSGGSDFSTALSKFPIFFDDLYCNLVKAGEQSGALDAMLDRIATYKEK
IEALKAKIRKAMTYPIAVVVVGIIVTAILLVKVVPVFEELFTSFGADLPAFTRFVVTLSEAAQKWWFVVLLGIALFGYLF
QSTHRKSQKFRDFIDRAILKIPVLGKILHKAAIARFARTLATTFSAGVPLVEALDSAAGAVGNVVYRNAIIQIRNGVSTG
QSLKNAIEMTGIFPNMTIQMIGIGEEAGSLEMMLDKVAEFYEREVDDAVDSLSSLMEPMIMVVLGTLVGGLVIAMYLPIF
QLGNVVG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=182390 A8C75_RS05335 WP_067379142.1 1217144..1218367(-) (pilC) [Marinobacterium aestuarii strain ST58-10]
ATGGCCACAAAACAAGTCAAACTGCAGACATTTGTCTGGCAGGGGCGAGACAAGAGCGGCAACGTTACCAAAGGCAAGCT
CGATGCTGCCAATGTCGCCACCGCACGGGCCCAATTGCGTCGCCAGGGCATTACGCCCAAAAAGGTTGGCAAAGAAAGCA
TTTCCATATTCAGCAACCGCAGTAAAGCCATCAAACCGCTGGATATTGCGTTCTTTACACGCCAGATGGCCACCATGCTG
AAATCCGGCGTGCCGCTGCTGCAGTCCCTGGAGATTGTCGCCGGTGGCTCTGAAAAAGACAAAATGAAAAAAATGCTCTA
TGACATTCGCAATGATGTCAGTGGCGGCTCGGACTTCTCCACCGCGCTCTCCAAGTTTCCGATATTCTTTGATGACCTCT
ACTGCAACCTGGTCAAGGCCGGTGAGCAATCCGGCGCCCTGGATGCCATGCTGGATCGCATTGCCACCTACAAGGAAAAA
ATCGAAGCCCTCAAAGCCAAGATCCGCAAAGCCATGACCTATCCGATAGCGGTCGTGGTGGTTGGTATTATTGTCACCGC
CATACTGCTGGTTAAGGTGGTGCCTGTATTTGAAGAGCTGTTCACCAGCTTTGGCGCCGACCTGCCCGCTTTTACCCGTT
TTGTCGTCACACTGTCGGAGGCGGCGCAGAAGTGGTGGTTTGTGGTTCTGCTGGGAATTGCTCTCTTTGGTTACCTGTTC
CAGAGCACGCACCGAAAATCACAGAAATTTCGTGATTTTATCGACCGTGCTATCTTGAAGATCCCAGTACTTGGCAAGAT
ATTGCACAAGGCGGCTATCGCCCGCTTCGCCCGCACCCTGGCAACCACCTTCTCCGCCGGTGTACCTCTGGTTGAGGCGC
TCGACTCGGCCGCAGGCGCCGTTGGCAACGTGGTCTATCGCAACGCCATCATCCAGATTCGTAACGGTGTCTCCACCGGC
CAATCCCTGAAAAATGCCATAGAGATGACCGGTATCTTCCCCAATATGACCATTCAGATGATCGGCATCGGTGAAGAAGC
GGGCTCCCTTGAGATGATGCTCGACAAGGTCGCTGAATTTTACGAGCGGGAGGTGGATGATGCGGTAGACTCGCTCTCCA
GCCTGATGGAACCCATGATCATGGTCGTGCTGGGCACCCTGGTGGGCGGCCTGGTTATTGCGATGTATCTGCCCATATTC
CAGCTGGGTAATGTTGTCGGTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1A9EVP8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

59.606

99.754

0.595
  pilC Acinetobacter baylyi ADP1

54.878

100

0.553
  pilC Acinetobacter baumannii D1279779

53.922

100

0.541
  pilC Legionella pneumophila strain ERS1305867

54.115

98.526

0.533
  pilC Vibrio campbellii strain DS40M4

43.032

100

0.432
  pilG Neisseria gonorrhoeae MS11

43.424

99.017

0.43
  pilG Neisseria meningitidis 44/76-A

42.893

98.526

0.423
  pilC Vibrio cholerae strain A1552

41.667

100

0.418
  pilC Thermus thermophilus HB27

39.454

99.017

0.391

Multiple sequence alignment