Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   A6V38_RS11285 Genome accession   NZ_CP015447
Coordinates   2142402..2142830 (-) Length   142 a.a.
NCBI ID   WP_000934385.1    Uniprot ID   A0A2K0CLZ8
Organism   Staphylococcus aureus strain M92     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2107167..2166875 2142402..2142830 within 0


Gene organization within MGE regions


Location: 2107167..2166875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6V38_RS10995 (A6V38_10980) scn 2107167..2107517 (-) 351 WP_000702263.1 complement inhibitor SCIN-A -
  A6V38_RS11005 (A6V38_10990) - 2107689..2108861 (+) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  A6V38_RS11010 (A6V38_10995) - 2109360..2109698 (-) 339 Protein_2033 SH3 domain-containing protein -
  A6V38_RS11030 (A6V38_11015) sak 2110346..2110837 (-) 492 WP_000920038.1 staphylokinase -
  A6V38_RS11035 (A6V38_11020) - 2111028..2111783 (-) 756 WP_000861038.1 CHAP domain-containing protein -
  A6V38_RS11040 (A6V38_11025) - 2111795..2112049 (-) 255 WP_000611512.1 phage holin -
  A6V38_RS11045 (A6V38_11030) - 2112101..2112208 (+) 108 WP_001791821.1 hypothetical protein -
  A6V38_RS11050 (A6V38_11035) pepG1 2112261..2112395 (-) 135 WP_000880502.1 type I toxin-antitoxin system toxin PepG1 -
  A6V38_RS11055 (A6V38_11040) - 2112580..2112954 (-) 375 WP_000340977.1 hypothetical protein -
  A6V38_RS11060 (A6V38_11045) - 2113010..2113297 (-) 288 WP_001262620.1 hypothetical protein -
  A6V38_RS11065 (A6V38_11050) - 2113343..2113495 (-) 153 WP_001000058.1 hypothetical protein -
  A6V38_RS11070 (A6V38_11055) - 2113488..2117270 (-) 3783 WP_000582132.1 phage tail spike protein -
  A6V38_RS11075 (A6V38_11060) - 2117286..2118776 (-) 1491 WP_001154317.1 phage distal tail protein -
  A6V38_RS11080 (A6V38_11065) - 2118776..2123425 (-) 4650 WP_031906215.1 phage tail tape measure protein -
  A6V38_RS11085 (A6V38_11070) gpGT 2123481..2123603 (-) 123 WP_000571956.1 phage tail assembly chaperone GT -
  A6V38_RS11090 (A6V38_11075) gpG 2123663..2124109 (-) 447 WP_000442601.1 phage tail assembly chaperone G -
  A6V38_RS11095 (A6V38_11080) - 2124174..2125127 (-) 954 WP_000570652.1 major tail protein -
  A6V38_RS11100 (A6V38_11085) - 2125128..2125508 (-) 381 WP_000611449.1 hypothetical protein -
  A6V38_RS11105 (A6V38_11090) - 2125505..2125882 (-) 378 WP_000501244.1 HK97-gp10 family putative phage morphogenesis protein -
  A6V38_RS11110 (A6V38_11095) - 2125882..2126217 (-) 336 WP_000975314.1 head-tail adaptor protein -
  A6V38_RS11115 (A6V38_11100) - 2126204..2126536 (-) 333 WP_031906214.1 head-tail connector protein -
  A6V38_RS11120 (A6V38_11105) - 2126545..2126703 (-) 159 WP_001252099.1 hypothetical protein -
  A6V38_RS11125 (A6V38_11110) - 2126739..2127986 (-) 1248 WP_000849957.1 phage major capsid protein -
  A6V38_RS11130 (A6V38_11115) - 2128074..2128658 (-) 585 WP_000032523.1 HK97 family phage prohead protease -
  A6V38_RS11135 (A6V38_11120) - 2128651..2129901 (-) 1251 WP_000511064.1 phage portal protein -
  A6V38_RS11140 (A6V38_11125) - 2129907..2130107 (-) 201 WP_000365301.1 hypothetical protein -
  A6V38_RS11145 (A6V38_11130) - 2130121..2131815 (-) 1695 WP_000133304.1 terminase large subunit -
  A6V38_RS11150 (A6V38_11135) - 2131818..2132285 (-) 468 WP_000919026.1 phage terminase small subunit P27 family -
  A6V38_RS11155 (A6V38_11140) - 2132413..2132757 (-) 345 WP_000817289.1 HNH endonuclease -
  A6V38_RS11160 (A6V38_11145) - 2132773..2133225 (-) 453 WP_000406191.1 nucleoside triphosphate pyrophosphohydrolase family protein -
  A6V38_RS11165 (A6V38_11150) - 2133340..2133810 (-) 471 WP_000282755.1 hypothetical protein -
  A6V38_RS11175 (A6V38_11160) - 2133833..2134033 (-) 201 WP_084939536.1 DUF1514 family protein -
  A6V38_RS11180 (A6V38_11165) rinB 2134033..2134182 (-) 150 WP_000595265.1 transcriptional activator RinB -
  A6V38_RS11185 (A6V38_11170) - 2134182..2134568 (-) 387 WP_001570808.1 hypothetical protein -
  A6V38_RS11190 (A6V38_11175) - 2134558..2134776 (-) 219 WP_000671662.1 hypothetical protein -
  A6V38_RS11195 (A6V38_11180) - 2134787..2134990 (-) 204 WP_000219344.1 hypothetical protein -
  A6V38_RS11200 (A6V38_11185) - 2134987..2135193 (-) 207 WP_000195768.1 DUF1381 domain-containing protein -
  A6V38_RS11205 (A6V38_11190) - 2135230..2135766 (-) 537 WP_000185669.1 dUTP diphosphatase -
  A6V38_RS11210 (A6V38_11195) - 2135759..2136007 (-) 249 WP_031895328.1 DUF1024 family protein -
  A6V38_RS11215 (A6V38_11200) - 2136000..2136308 (-) 309 WP_000144710.1 hypothetical protein -
  A6V38_RS11220 (A6V38_11205) - 2136305..2136652 (-) 348 WP_000979209.1 YopX family protein -
  A6V38_RS11225 (A6V38_11210) - 2136649..2137050 (-) 402 WP_000695759.1 hypothetical protein -
  A6V38_RS11230 (A6V38_11215) - 2137053..2137259 (-) 207 WP_000693987.1 hypothetical protein -
  A6V38_RS11235 (A6V38_11220) - 2137273..2137521 (-) 249 WP_078150933.1 SAV1978 family virulence-associated passenger protein -
  A6V38_RS11240 (A6V38_11225) - 2137521..2137775 (-) 255 WP_000022735.1 DUF3310 domain-containing protein -
  A6V38_RS11245 (A6V38_11230) - 2137775..2138135 (-) 361 Protein_2076 SA1788 family PVL leukocidin-associated protein -
  A6V38_RS11250 (A6V38_11235) - 2138136..2138321 (-) 186 WP_001187264.1 DUF3113 family protein -
  A6V38_RS11255 (A6V38_11240) - 2138321..2138728 (-) 408 WP_000401950.1 RusA family crossover junction endodeoxyribonuclease -
  A6V38_RS11260 (A6V38_11245) - 2138738..2138959 (-) 222 WP_001123684.1 DUF3269 family protein -
  A6V38_RS16160 - 2138972..2139133 (-) 162 WP_000237154.1 hypothetical protein -
  A6V38_RS11265 (A6V38_11255) - 2139127..2139906 (-) 780 WP_053012518.1 ATP-binding protein -
  A6V38_RS11270 (A6V38_11260) - 2139916..2140686 (-) 771 WP_031783365.1 conserved phage C-terminal domain-containing protein -
  A6V38_RS11275 (A6V38_11265) - 2140751..2141608 (+) 858 WP_000371250.1 DUF4393 domain-containing protein -
  A6V38_RS11280 (A6V38_11270) - 2141714..2142388 (-) 675 WP_084939537.1 putative HNHc nuclease -
  A6V38_RS11285 (A6V38_11275) ssbA 2142402..2142830 (-) 429 WP_000934385.1 single-stranded DNA-binding protein Machinery gene
  A6V38_RS11290 (A6V38_11280) - 2142830..2143453 (-) 624 WP_000139720.1 DUF1071 domain-containing protein -
  A6V38_RS11295 (A6V38_11285) - 2143446..2143667 (-) 222 WP_000815401.1 DUF2483 family protein -
  A6V38_RS11300 (A6V38_11290) - 2143677..2143937 (-) 261 WP_015977954.1 DUF1108 family protein -
  A6V38_RS11305 (A6V38_11295) - 2144031..2144351 (-) 321 WP_000219666.1 hypothetical protein -
  A6V38_RS11310 (A6V38_11300) - 2144352..2144519 (-) 168 WP_000066022.1 DUF1270 domain-containing protein -
  A6V38_RS11315 (A6V38_11305) - 2144531..2144794 (-) 264 WP_001124198.1 helix-turn-helix domain-containing protein -
  A6V38_RS16305 - 2144943..2145042 (-) 100 Protein_2092 hypothetical protein -
  A6V38_RS11325 (A6V38_11315) - 2145058..2145810 (-) 753 WP_001148641.1 phage antirepressor KilAC domain-containing protein -
  A6V38_RS11330 (A6V38_11320) - 2145967..2146275 (-) 309 WP_001153965.1 hypothetical protein -
  A6V38_RS11335 (A6V38_11325) - 2146290..2146508 (-) 219 WP_001198673.1 helix-turn-helix transcriptional regulator -
  A6V38_RS11340 (A6V38_11330) - 2146650..2147369 (+) 720 WP_000358221.1 XRE family transcriptional regulator -
  A6V38_RS11345 (A6V38_11335) - 2147569..2147751 (+) 183 WP_000705240.1 hypothetical protein -
  A6V38_RS11350 (A6V38_11340) - 2147787..2147933 (+) 147 WP_001013104.1 hypothetical protein -
  A6V38_RS11355 (A6V38_11345) - 2147930..2148544 (-) 615 WP_000191459.1 hypothetical protein -
  A6V38_RS11360 (A6V38_11350) - 2148652..2149689 (+) 1038 WP_084939538.1 site-specific integrase -
  A6V38_RS11365 (A6V38_11355) sph 2149746..2150570 (+) 825 Protein_2101 sphingomyelin phosphodiesterase -
  A6V38_RS11370 (A6V38_11360) lukG 2150808..2151824 (-) 1017 WP_000595324.1 bi-component leukocidin LukGH subunit G -
  A6V38_RS11375 (A6V38_11365) lukH 2151846..2152901 (-) 1056 WP_000791407.1 bi-component leukocidin LukGH subunit H -
  A6V38_RS11380 (A6V38_11370) - 2153336..2154559 (+) 1224 WP_000206638.1 ArgE/DapE family deacylase -
  A6V38_RS11385 (A6V38_11380) - 2154931..2155776 (-) 846 WP_000812008.1 class I SAM-dependent methyltransferase -
  A6V38_RS11390 (A6V38_11385) - 2155838..2156749 (-) 912 WP_000825510.1 iron-hydroxamate ABC transporter substrate-binding protein -
  A6V38_RS11395 (A6V38_11390) - 2156910..2158217 (+) 1308 WP_001045079.1 TrkH family potassium uptake protein -
  A6V38_RS11405 (A6V38_11400) - 2159070..2159513 (-) 444 WP_000022887.1 GNAT family N-acetyltransferase -
  A6V38_RS11410 (A6V38_11405) - 2159619..2160055 (-) 437 Protein_2109 hypothetical protein -
  A6V38_RS11415 (A6V38_11410) - 2160373..2160963 (-) 591 WP_001293058.1 terminase small subunit -
  A6V38_RS11420 (A6V38_11415) - 2160960..2161172 (-) 213 WP_000128898.1 LuxR C-terminal-related transcriptional regulator -
  A6V38_RS11425 (A6V38_11420) - 2161233..2161779 (+) 547 Protein_2112 site-specific integrase -
  A6V38_RS11430 (A6V38_11425) groL 2161874..2163490 (-) 1617 WP_000240653.1 chaperonin GroEL -
  A6V38_RS11435 (A6V38_11430) groES 2163566..2163850 (-) 285 WP_000917288.1 co-chaperone GroES -
  A6V38_RS11440 (A6V38_11435) mroQ 2164025..2164768 (+) 744 WP_000197635.1 CPBP family intramembrane glutamic endopeptidase MroQ -
  A6V38_RS11445 (A6V38_11440) - 2164793..2166052 (-) 1260 WP_000120305.1 SdrH family protein -
  A6V38_RS11450 (A6V38_11445) - 2166249..2166875 (+) 627 WP_000522384.1 nitroreductase family protein -

Sequence


Protein


Download         Length: 142 a.a.        Molecular weight: 15872.58 Da        Isoelectric Point: 8.4825

>NTDB_id=179941 A6V38_RS11285 WP_000934385.1 2142402..2142830(-) (ssbA) [Staphylococcus aureus strain M92]
MLNRAVLVGRLTKDPELRSAPNGVNVGTFTLAVNRTFTNAQGEREADFINVVVFKKQAENVKNYLSKGSLAGVDGRLQTR
SYENKVGQRVFVTEVVADSVQFLEPKNNNQQPNNNYHQQRQTQTGNNPFDNTTAITDDDLPF

Nucleotide


Download         Length: 429 bp        

>NTDB_id=179941 A6V38_RS11285 WP_000934385.1 2142402..2142830(-) (ssbA) [Staphylococcus aureus strain M92]
ATGTTAAACAGAGCAGTATTAGTAGGACGCTTAACAAAAGACCCAGAATTAAGAAGCGCGCCAAATGGCGTAAATGTAGG
TACATTCACATTGGCAGTAAACAGAACATTCACGAATGCTCAAGGCGAGCGTGAAGCAGATTTTATAAACGTAGTAGTGT
TCAAGAAACAAGCTGAAAATGTTAAAAACTACCTTTCTAAAGGGTCGCTGGCAGGTGTAGACGGGCGACTACAAACACGT
AGCTACGAAAATAAAGTCGGGCAACGTGTATTTGTGACAGAAGTAGTAGCGGACAGTGTTCAATTCTTAGAACCGAAGAA
TAACAACCAACAACCAAACAACAATTATCATCAACAAAGACAAACTCAAACTGGTAATAATCCTTTTGATAATACCACTG
CGATTACTGATGATGACTTACCGTTCTGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A2K0CLZ8

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

58.14

100

0.704

  ssb Latilactobacillus sakei subsp. sakei 23K

50.588

100

0.606

  ssbB Bacillus subtilis subsp. subtilis str. 168

58.491

74.648

0.437

  ssbB Streptococcus sobrinus strain NIDR 6715-7

41.958

100

0.423

  ssbA Streptococcus mutans UA159

40.845

100

0.408

  ssbB/cilA Streptococcus mitis NCTC 12261

40.141

100

0.401

  ssbB/cilA Streptococcus pneumoniae TIGR4

40.141

100

0.401

  ssbB/cilA Streptococcus pneumoniae Rx1

39.437

100

0.394

  ssbB/cilA Streptococcus pneumoniae D39

39.437

100

0.394

  ssbB/cilA Streptococcus pneumoniae R6

39.437

100

0.394

  ssbB/cilA Streptococcus mitis SK321

39.437

100

0.394


Multiple sequence alignment