Detailed information NTG0169969

Bioinformatically predicted

Overview

• Name: comE
• Type: Regulator
• Locus tag: AXE83_RS00195
• Genome accession: NZ_CP014264
• Coordinates: 43962..44714 (-)
• Length: 250 a.a.
• NCBI ID: WP_049530388.1
• Uniprot ID: -
• Organism: Streptococcus sp. oral taxon 431 strain F0610 (5-114)
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 38962..49714

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AXE83_RS00180 (AXE83_00180)	-	40222..42885 (-)	2664	WP_060954974.1	YhgE/Pip domain-containing protein	-
AXE83_RS00185 (AXE83_00185)	-	43014..43556 (+)	543	WP_060954975.1	TetR/AcrR family transcriptional regulator C-terminal domain-containing protein	-
AXE83_RS00195 (AXE83_00195)	comE	43962..44714 (-)	753	WP_049530388.1	competence system response regulator transcription factor ComE	Regulator
AXE83_RS00200 (AXE83_00200)	comD	44711..46030 (-)	1320	WP_060954976.1	competence system sensor histidine kinase ComD	Regulator
AXE83_RS10325	comC	46053..46187 (-)	135	WP_080936286.1	competence-stimulating peptide ComC	-
AXE83_RS00210 (AXE83_00210)	rlmH	46470..46949 (-)	480	WP_060954977.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
AXE83_RS00215 (AXE83_00215)	htrA	47133..48317 (+)	1185	WP_060954978.1	trypsin-like peptidase domain-containing protein	Regulator
AXE83_RS00220 (AXE83_00220)	spo0J	48374..49132 (+)	759	WP_049508355.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 250 a.a.
• Molecular weight: 29634.07 Da
• Isoelectric Point: 8.5500

>NTDB_id=169969 AXE83_RS00195 WP_049530388.1 43962..44714(-) (comE) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MKVLILEDIIEHQVRLETTLNKISKETNIPISYKTTGKVREFMEYVEHDEVNQLYFLDIDINGIERKGFEVAQFIRHRNP
YAIIVFITSRSEFATLTYKYKVSALDFIDKETSDQVFKNRVADCVLYTKTTLLENQSVVDYFDYSYKGNDLCIPYHDILY
IETTGTSHKLRIVGKNFAKEFYGTMTDIQEKDKETQRFYLAHKSFLVNIGNVREIDRKKMEVVFYEDHRCPISRLKTKKL
RELMAKNQKK

Nucleotide

• Length: 753 bp

>NTDB_id=169969 AXE83_RS00195 WP_049530388.1 43962..44714(-) (comE) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGAAAGTATTGATTTTAGAAGATATTATAGAACACCAAGTAAGGTTGGAAACAACTCTAAATAAAATTTCTAAGGAAAC
AAATATTCCTATCTCCTATAAAACAACAGGAAAAGTAAGAGAATTTATGGAATATGTAGAGCATGATGAAGTCAATCAGC
TTTATTTTCTAGATATTGATATCAATGGGATTGAGAGAAAAGGATTTGAGGTTGCTCAATTTATTCGTCACCGCAATCCT
TATGCCATTATTGTTTTTATTACAAGTCGATCTGAATTTGCTACCTTGACTTATAAATACAAAGTTTCAGCATTGGATTT
CATTGATAAAGAAACCAGTGATCAAGTTTTTAAAAATAGAGTTGCCGACTGTGTGCTTTACACTAAGACTACTTTACTTG
AAAACCAATCAGTCGTTGATTATTTTGATTATAGTTACAAAGGAAATGATCTTTGTATTCCTTATCATGATATTCTCTAC
ATTGAAACAACTGGAACTTCTCATAAATTACGGATTGTAGGTAAGAATTTTGCAAAAGAATTCTATGGAACAATGACAGA
TATTCAAGAAAAGGATAAGGAAACCCAACGTTTTTATCTAGCTCACAAGTCATTTTTAGTCAATATTGGTAATGTGAGAG
AAATTGATCGTAAAAAAATGGAAGTTGTATTTTATGAAGATCATCGTTGTCCTATCTCTCGTCTAAAAACAAAAAAATTG
AGAGAACTAATGGCTAAAAACCAAAAAAAGTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-120)

• LytTr DNA-binding domain (LytTR) (152-244)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Streptococcus mitis NCTC 12261	79.6	100	0.796
comE	Streptococcus infantis strain Atu-4	79.2	100	0.792
comE	Streptococcus mitis SK321	79.2	100	0.792
comE	Streptococcus pneumoniae Rx1	79.2	100	0.792
comE	Streptococcus pneumoniae D39	79.2	100	0.792
comE	Streptococcus pneumoniae R6	79.2	100	0.792
comE	Streptococcus pneumoniae TIGR4	79.2	100	0.792
comE/comE2	Streptococcus gordonii strain NCTC7865	61.6	100	0.616
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	61.6	100	0.616
comE/blpR	Streptococcus mutans UA159	40.079	100	0.404