Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   AVT04_RS05755 Genome accession   NZ_CP013939
Coordinates   1067502..1068443 (+) Length   313 a.a.
NCBI ID   WP_011226629.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S9     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1062502..1073443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AVT04_RS05745 (AVT04_05745) rpoC 1063262..1066900 (+) 3639 WP_011226631.1 DNA-directed RNA polymerase subunit beta' -
  AVT04_RS05750 (AVT04_05750) - 1067059..1067421 (+) 363 WP_011226630.1 DUF1033 family protein -
  AVT04_RS05755 (AVT04_05755) comGA/cglA/cilD 1067502..1068443 (+) 942 WP_011226629.1 competence type IV pilus ATPase ComGA Machinery gene
  AVT04_RS05760 (AVT04_05760) comYB 1068325..1069425 (+) 1101 WP_148148900.1 competence type IV pilus assembly protein ComGB Machinery gene
  AVT04_RS05765 (AVT04_05765) comYC 1069422..1069748 (+) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  AVT04_RS05770 (AVT04_05770) comYD 1069708..1070136 (+) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  AVT04_RS05775 (AVT04_05775) comGE 1070108..1070401 (+) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  AVT04_RS05780 (AVT04_05780) comYF 1070385..1070822 (+) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  AVT04_RS05785 (AVT04_05785) comGG 1070800..1071117 (+) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG -
  AVT04_RS05790 (AVT04_05790) comYH 1071162..1072118 (+) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  AVT04_RS05795 (AVT04_05795) - 1072174..1073367 (+) 1194 Protein_1053 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35422.56 Da        Isoelectric Point: 6.3927

>NTDB_id=166333 AVT04_RS05755 WP_011226629.1 1067502..1068443(+) (comGA/cglA/cilD) [Streptococcus thermophilus strain S9]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMNYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=166333 AVT04_RS05755 WP_011226629.1 1067502..1068443(+) (comGA/cglA/cilD) [Streptococcus thermophilus strain S9]
ATGGTAACAGAATTTGCTAAGGAAATGATAAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTTTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTTCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCTATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGCGATTGATAT
GAACTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTCTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGAGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCTACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

99.361

0.649
  comYA Streptococcus mutans UA159

64.537

100

0.645
  comYA Streptococcus mutans UA140

64.537

100

0.645
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.987

99.361

0.636
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.218

99.681

0.61
  comGA Lactococcus lactis subsp. cremoris KW2

51.125

99.361

0.508
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377

Multiple sequence alignment