Detailed information NTG0163389

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: ATM98_RS00945
• Genome accession: NZ_CP013651
• Coordinates: 164479..165156 (+)
• Length: 225 a.a.
• NCBI ID: WP_061563754.1
• Uniprot ID: -
• Organism: Streptococcus sp. A12
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 159479..170156

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ATM98_RS00925 (ATM98_00925)	-	160034..160321 (-)	288	WP_061563750.1	GIY-YIG nuclease family protein	-
ATM98_RS00930 (ATM98_00930)	-	160311..161057 (-)	747	WP_061563751.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
ATM98_RS00935 (ATM98_00935)	-	161156..163495 (-)	2340	WP_061563752.1	cation-translocating P-type ATPase	-
ATM98_RS00940 (ATM98_00940)	-	163633..164376 (+)	744	WP_061563753.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
ATM98_RS00945 (ATM98_00945)	comEA/celA/cilE	164479..165156 (+)	678	WP_061563754.1	helix-hairpin-helix domain-containing protein	Machinery gene
ATM98_RS00950 (ATM98_00950)	comEC/celB	165140..167380 (+)	2241	WP_061563755.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ATM98_RS00955 (ATM98_00955)	-	167443..168108 (+)	666	WP_061563756.1	DUF805 domain-containing protein	-
ATM98_RS00960 (ATM98_00960)	holA	168086..169123 (+)	1038	WP_061563757.1	DNA polymerase III subunit delta	-
ATM98_RS00965 (ATM98_00965)	sodA	169195..169800 (+)	606	WP_048689195.1	superoxide dismutase SodA	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 24417.49 Da
• Isoelectric Point: 4.5766

>NTDB_id=163389 ATM98_RS00945 WP_061563754.1 164479..165156(+) (comEA/celA/cilE) [Streptococcus sp. A12]
METWIEKLKEYKLFLGLAAVGLVMGGVFLFWPKQPPQAPETVISQLEMVDQEASPKEDTSLPSSSQQRSEEKTDSSQEKI
MVDVKGAVRQAGVYELPVGSRVYDAVQKAGGMTDEANSQSVNLAQKLEDESIVYVAKNGEEVAPVASASAGTTGGEKQLK
DGKVNLNTATEAELQTISGIGQKRAQDIIAYREEKGKFQSIDELKNVSGIGQKTLEKLKEHVTVD

Nucleotide

• Length: 678 bp

>NTDB_id=163389 ATM98_RS00945 WP_061563754.1 164479..165156(+) (comEA/celA/cilE) [Streptococcus sp. A12]
ATGGAGACGTGGATTGAGAAGCTCAAGGAATATAAACTGTTTTTAGGTTTGGCTGCTGTGGGGCTAGTAATGGGAGGAGT
ATTTCTCTTTTGGCCTAAGCAACCTCCACAAGCACCGGAAACTGTCATTTCCCAGTTAGAAATGGTGGATCAGGAGGCTT
CTCCTAAGGAAGACACTAGCCTCCCTTCTAGCTCTCAACAGAGGAGTGAGGAAAAGACGGACTCCTCTCAAGAGAAAATC
ATGGTGGATGTGAAGGGAGCTGTCAGACAAGCAGGGGTCTACGAACTTCCAGTGGGGAGCCGGGTCTATGATGCGGTCCA
AAAAGCAGGAGGGATGACAGACGAAGCCAACAGCCAATCCGTCAACTTAGCGCAAAAATTGGAGGATGAGTCCATCGTCT
ATGTTGCTAAGAATGGAGAGGAGGTAGCGCCTGTTGCATCTGCATCTGCTGGGACGACCGGTGGCGAAAAGCAGTTAAAA
GATGGAAAGGTCAATCTCAATACGGCAACAGAAGCAGAACTACAGACGATTTCTGGGATAGGTCAAAAGCGAGCCCAAGA
TATCATTGCTTATCGAGAGGAAAAAGGAAAATTTCAGTCTATTGATGAACTGAAAAATGTTTCTGGGATTGGCCAAAAGA
CGTTAGAAAAGTTAAAAGAGCATGTTACAGTGGATTAG

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (162-223)

• SLBB domain (SLBB) (81-133)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	49.78	100	0.502
comEA/celA/cilE	Streptococcus mitis NCTC 12261	49.333	100	0.493
comEA/celA/cilE	Streptococcus pneumoniae Rx1	48.889	100	0.489
comEA/celA/cilE	Streptococcus pneumoniae D39	48.889	100	0.489
comEA/celA/cilE	Streptococcus pneumoniae R6	48.889	100	0.489
comEA/celA/cilE	Streptococcus mitis SK321	48.889	100	0.489
comEA	Streptococcus thermophilus LMD-9	44.737	100	0.453
comEA	Bacillus subtilis subsp. subtilis str. 168	40	97.778	0.391
comEA	Lactococcus lactis subsp. cremoris KW2	37.719	100	0.382
comEA	Latilactobacillus sakei subsp. sakei 23K	33.607	100	0.364