Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   RN80_RS03215 Genome accession   NZ_CP012646
Coordinates   613120..614376 (+) Length   418 a.a.
NCBI ID   WP_060627460.1    Uniprot ID   -
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 608120..619376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS03190 (RN80_03200) ndk 609738..610160 (+) 423 WP_060628748.1 nucleoside-diphosphate kinase -
  RN80_RS03195 (RN80_03205) comM 610294..610923 (+) 630 WP_060627452.1 hypothetical protein Regulator
  RN80_RS03200 (RN80_03210) tsaE 611020..611463 (+) 444 WP_060627454.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  RN80_RS03205 (RN80_03215) - 611453..611971 (+) 519 WP_060627456.1 GNAT family N-acetyltransferase -
  RN80_RS03210 (RN80_03220) brpA 611979..613031 (+) 1053 WP_060627458.1 biofilm formation/cell division transcriptional regulator BrpA -
  RN80_RS03215 (RN80_03225) cinA 613120..614376 (+) 1257 WP_060627460.1 competence/damage-inducible protein A Machinery gene
  RN80_RS03220 (RN80_03230) recA 614431..615597 (+) 1167 WP_060627462.1 recombinase RecA Machinery gene
  RN80_RS03225 (RN80_03235) - 615712..617082 (+) 1371 WP_060627463.1 MATE family efflux transporter -
  RN80_RS03230 (RN80_03240) - 617179..617895 (+) 717 WP_000532882.1 YebC/PmpR family DNA-binding transcriptional regulator -
  RN80_RS03235 (RN80_03245) - 618073..618543 (+) 471 WP_060627465.1 MarR family winged helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44855.14 Da        Isoelectric Point: 4.5990

>NTDB_id=156003 RN80_RS03215 WP_060627460.1 613120..614376(+) (cinA) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSNLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDVFFAQRPDYARTSNNERQAQIVEGATPLPNETGLAVGGILEVDGVTYVVLPGPPSEMKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQTDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILGNQI
LDCQTFEGISLRDLCYGYGEEASLASIVVEELKKQGKTITAAESLTAGLFQATVADFSGASSIFKGGFVTYSLEEKSKML
DIPVKDLEEQGVVSEFTAQKMAEQARSKTQSDFGLSLTGVAGPDSLEGHPAGTVFIGLAQEHGTKVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=156003 RN80_RS03215 WP_060627460.1 613120..614376(+) (cinA) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGGCAGATTGTCAATACCAATGCTCAGTTTTTATCGGA
AAAACTAGCAGAGATTGGGGTAGACGTATATTTTCAGACGGCTGTAGGAGACAATGAAGCTCGTCTCTTGTCTTTGCTCG
AAATTGCCAGTCAACGGAGCAATCTGGTGATTTTAACAGGTGGTTTGGGGCCAACTGAGGACGATTTGACCAAACAAACT
TTGGCTAAATTCTTAGGGAAAGCATTAGTCTTCGATCCTCAGGCACAGGAGAAGTTGGATGTCTTTTTTGCCCAGCGACC
AGACTATGCCCGAACATCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGACTCCGCTGCCCAACGAAACAGGAC
TGGCTGTGGGAGGAATATTGGAAGTCGATGGAGTGACCTATGTCGTCCTTCCAGGTCCACCAAGTGAAATGAAACCTATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGTTGTATTCCCGAGTTCTTCGTTTCTTTGGAATTGGCGA
AAGTCAGCTGGTGACGATTTTGGCTGATTTGATTGATAATCAAACAGATCCGACCTTGGCCCCTTATGCTAAGACAGGAG
AAGTCACTCTGCGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGGAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACCTCTGTTATGGTTATGGAGAGGAGGCTAGCTTGGCCAGCAT
TGTGGTAGAAGAACTGAAAAAACAAGGGAAAACTATCACGGCTGCAGAGAGTTTGACGGCAGGGCTTTTCCAAGCTACTG
TGGCGGATTTTTCAGGAGCTTCAAGTATATTTAAGGGTGGTTTCGTGACCTATAGCCTGGAGGAAAAATCAAAGATGTTG
GATATTCCTGTCAAGGACTTGGAAGAACAGGGTGTGGTATCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCAGATTTTGGCCTTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTCGAAGGACACCCGGCTGGAACAG
TCTTCATAGGCTTGGCACAGGAGCATGGAACTAAGGTCATCAAGGTTAATATTGGAGGTAGAAGTCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

97.368

100

0.974
  cinA Streptococcus mitis NCTC 12261

95.215

100

0.952
  cinA Streptococcus pneumoniae TIGR4

93.78

100

0.938
  cinA Streptococcus pneumoniae Rx1

93.541

100

0.935
  cinA Streptococcus pneumoniae R6

93.541

100

0.935
  cinA Streptococcus pneumoniae D39

93.301

100

0.933
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

44.498

100

0.445

Multiple sequence alignment