Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   PGR6_RS24370 Genome accession   NZ_CP011567
Coordinates   5516379..5517596 (+) Length   405 a.a.
NCBI ID   WP_018930188.1    Uniprot ID   A0A2W7JC57
Organism   Pseudomonas sp. GR 6-02     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 5511379..5522596
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PGR6_RS24350 (PGR6_49120) - 5512886..5513182 (+) 297 WP_064620386.1 DUF2845 domain-containing protein -
  PGR6_RS24355 (PGR6_49130) - 5513356..5513712 (-) 357 WP_064620389.1 BON domain-containing protein -
  PGR6_RS24360 (PGR6_49140) - 5514039..5514449 (-) 411 WP_019650990.1 pilin -
  PGR6_RS24365 (PGR6_49150) pilB 5514676..5516376 (+) 1701 WP_064620392.1 type IV-A pilus assembly ATPase PilB Machinery gene
  PGR6_RS24370 (PGR6_49160) pilC 5516379..5517596 (+) 1218 WP_018930188.1 type II secretion system F family protein Machinery gene
  PGR6_RS24375 (PGR6_49170) pilD 5517598..5518470 (+) 873 WP_064620394.1 A24 family peptidase Machinery gene
  PGR6_RS24380 (PGR6_49180) coaE 5518467..5519090 (+) 624 WP_026286732.1 dephospho-CoA kinase -
  PGR6_RS24385 (PGR6_49190) yacG 5519087..5519287 (+) 201 WP_007938961.1 DNA gyrase inhibitor YacG -
  PGR6_RS24390 (PGR6_49200) - 5519297..5519512 (-) 216 WP_007938959.1 hypothetical protein -
  PGR6_RS24395 (PGR6_49210) - 5519576..5520265 (-) 690 WP_018930184.1 energy-coupling factor ABC transporter permease -
  PGR6_RS24400 (PGR6_49220) - 5521146..5521388 (+) 243 WP_018930181.1 DUF2790 domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44096.94 Da        Isoelectric Point: 9.8911

>NTDB_id=146942 PGR6_RS24370 WP_018930188.1 5516379..5517596(+) (pilC) [Pseudomonas sp. GR 6-02]
MAVKAAKISVYAWEGTDRKGAKMTGELTGQNPALIKAQLRKQGINPGKVRKKYASIFSAGKRIKPLDIALFTRQMATMMK
AGVPLLQSFEIIGEGFDNPNMRKLVDEVKQEVAAGNSFAAALRKKPQYFDELYCNLVDAGEQAGALDTLLERVATYKEKS
ESLKAKIKKAMTYPLAVVFVAIIVTGILLVKVVPQFQSVFSGFGAELPAFTVMVIGLSEFMQDWWWMILGVLAGGIFGLR
HAFKNSPGFRDRTDTWLLKLPLVGALMYKSAVARYARTLSTTFAAGVPLVEALESVAGATGNIVFKRAVLRIKQDVSTGM
QLNFSMRTSGIFPTMAIQMTAIGEESGALDDMLDKVAGFYEAEVDNMVDNLTSLMEPFIMVVLGVIVGGLVVAMYLPIFQ
LGSAV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=146942 PGR6_RS24370 WP_018930188.1 5516379..5517596(+) (pilC) [Pseudomonas sp. GR 6-02]
ATGGCGGTCAAAGCAGCGAAAATCAGCGTGTATGCCTGGGAAGGCACGGATCGCAAAGGTGCGAAAATGACCGGCGAGTT
GACCGGACAAAATCCAGCGCTGATCAAGGCCCAGTTGCGCAAGCAGGGCATCAATCCGGGCAAGGTGCGGAAAAAGTACG
CGTCCATTTTCAGTGCCGGCAAGCGCATCAAACCCTTGGACATCGCCCTGTTTACCCGGCAGATGGCGACCATGATGAAA
GCCGGCGTACCGCTCCTGCAATCGTTCGAGATCATCGGCGAAGGCTTCGATAACCCGAACATGCGCAAGCTGGTGGACGA
GGTGAAACAGGAAGTCGCGGCCGGTAACAGCTTCGCCGCGGCCCTGCGCAAAAAGCCCCAGTATTTCGACGAGCTGTACT
GCAACCTGGTGGACGCCGGCGAGCAGGCCGGTGCCCTGGATACCCTGCTGGAACGGGTGGCGACCTACAAGGAAAAGAGC
GAAAGCCTCAAGGCCAAGATCAAGAAAGCCATGACCTACCCGCTGGCCGTGGTGTTCGTCGCAATCATTGTGACCGGCAT
TCTGCTGGTCAAGGTTGTGCCGCAATTCCAGTCGGTATTCTCGGGGTTCGGCGCCGAACTGCCGGCGTTCACCGTGATGG
TCATCGGCTTGTCGGAGTTCATGCAGGACTGGTGGTGGATGATACTCGGCGTGTTGGCTGGGGGGATCTTCGGCCTGCGC
CATGCCTTCAAGAATTCCCCGGGCTTTCGCGACCGGACGGACACCTGGCTGCTGAAACTGCCGTTGGTTGGCGCGCTCAT
GTACAAGTCCGCCGTGGCCCGTTACGCCCGCACCCTGTCGACGACGTTTGCCGCCGGCGTGCCACTGGTCGAAGCCCTTG
AGTCAGTGGCGGGCGCGACCGGCAATATCGTGTTCAAGCGAGCGGTGTTGCGCATCAAGCAGGACGTTTCGACCGGCATG
CAGCTGAATTTTTCCATGCGTACCTCCGGCATCTTTCCGACCATGGCGATCCAGATGACGGCCATTGGCGAAGAGTCCGG
CGCGCTGGACGACATGCTCGACAAGGTCGCGGGTTTCTATGAGGCCGAGGTGGACAACATGGTCGATAACCTGACCAGCC
TGATGGAGCCGTTCATCATGGTGGTACTGGGTGTTATCGTCGGCGGGCTGGTGGTTGCAATGTACCTGCCCATCTTCCAA
CTCGGCTCAGCGGTCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)

Type II secretion system (T2SS), protein F (T2SSF)

(276-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2W7JC57

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

74.321

100

0.743
  pilC Acinetobacter baylyi ADP1

61.029

100

0.615
  pilC Acinetobacter baumannii D1279779

59.559

100

0.6
  pilC Legionella pneumophila strain ERS1305867

53.535

97.778

0.523
  pilG Neisseria gonorrhoeae MS11

42.289

99.259

0.42
  pilC Vibrio cholerae strain A1552

42.677

97.778

0.417
  pilG Neisseria meningitidis 44/76-A

41.791

99.259

0.415
  pilC Vibrio campbellii strain DS40M4

40.64

100

0.407
  pilC Thermus thermophilus HB27

37.905

99.012

0.375

Multiple sequence alignment