Detailed information NTG0146943

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: PGR6_RS24375
• Genome accession: NZ_CP011567
• Coordinates: 5517598..5518470 (+)
• Length: 290 a.a.
• NCBI ID: WP_064620394.1
• Uniprot ID: A0A2W7LA92
• Organism: Pseudomonas sp. GR 6-02
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 5512598..5523470

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PGR6_RS24350 (PGR6_49120)	-	5512886..5513182 (+)	297	WP_064620386.1	DUF2845 domain-containing protein	-
PGR6_RS24355 (PGR6_49130)	-	5513356..5513712 (-)	357	WP_064620389.1	BON domain-containing protein	-
PGR6_RS24360 (PGR6_49140)	-	5514039..5514449 (-)	411	WP_019650990.1	pilin	-
PGR6_RS24365 (PGR6_49150)	pilB	5514676..5516376 (+)	1701	WP_064620392.1	type IV-A pilus assembly ATPase PilB	Machinery gene
PGR6_RS24370 (PGR6_49160)	pilC	5516379..5517596 (+)	1218	WP_018930188.1	type II secretion system F family protein	Machinery gene
PGR6_RS24375 (PGR6_49170)	pilD	5517598..5518470 (+)	873	WP_064620394.1	A24 family peptidase	Machinery gene
PGR6_RS24380 (PGR6_49180)	coaE	5518467..5519090 (+)	624	WP_026286732.1	dephospho-CoA kinase	-
PGR6_RS24385 (PGR6_49190)	yacG	5519087..5519287 (+)	201	WP_007938961.1	DNA gyrase inhibitor YacG	-
PGR6_RS24390 (PGR6_49200)	-	5519297..5519512 (-)	216	WP_007938959.1	hypothetical protein	-
PGR6_RS24395 (PGR6_49210)	-	5519576..5520265 (-)	690	WP_018930184.1	energy-coupling factor ABC transporter permease	-
PGR6_RS24400 (PGR6_49220)	-	5521146..5521388 (+)	243	WP_018930181.1	DUF2790 domain-containing protein	-
PGR6_RS24405 (PGR6_49230)	-	5521398..5522666 (-)	1269	WP_064620397.1	OprD family porin	-

Sequence

Protein

• Length: 290 a.a.
• Molecular weight: 32228.50 Da
• Isoelectric Point: 7.6846

>NTDB_id=146943 PGR6_RS24375 WP_064620394.1 5517598..5518470(+) (pilD) [Pseudomonas sp. GR 6-02]
MSLNEFLSLNPLAFVMTAGLIGLLIGSFLNVVVWRLPKMLEREWRLQAHDVLDLPVEAPGPTYNLILPHSECPHCGHRIR
VWENIPILSYLFLRGRCSSCAAPISKRYPLTELACGLLSAFVAWHFGFGWQACMVLVLSWGLLAMSLIDAEHQLLPDVLV
MPLMWLGLVLNSFGLFVSLHDAFWGAVAGYMALWTVFWLFKLVTGKDGIGYGDFKLLAMLGAWGGWQILPMTILLSSLVG
AILGVILLRLRDAKTSTPLPFGPYLAIAGWIALLWGGQITGFYWQFVGLK

Nucleotide

• Length: 873 bp

>NTDB_id=146943 PGR6_RS24375 WP_064620394.1 5517598..5518470(+) (pilD) [Pseudomonas sp. GR 6-02]
ATGTCCTTGAACGAATTTCTGAGCCTCAACCCGCTGGCCTTCGTGATGACCGCAGGGCTGATCGGCCTGCTGATCGGCAG
TTTTCTCAACGTGGTGGTCTGGCGCCTGCCGAAAATGCTTGAGCGTGAATGGCGCCTGCAGGCCCATGACGTACTGGACT
TGCCAGTCGAAGCCCCCGGTCCGACCTACAACCTGATATTGCCCCACTCCGAGTGTCCTCACTGCGGCCATCGGATTCGA
GTGTGGGAGAACATTCCAATACTCAGTTATCTGTTTTTACGTGGGCGATGCTCGAGCTGCGCAGCGCCGATCAGTAAACG
TTACCCGCTGACCGAACTGGCCTGCGGCCTGCTGTCGGCGTTCGTCGCCTGGCATTTCGGTTTCGGCTGGCAGGCCTGCA
TGGTGCTGGTCCTGAGTTGGGGCCTGCTGGCGATGAGCCTGATCGATGCCGAACATCAACTGTTGCCGGACGTACTGGTG
ATGCCATTGATGTGGCTGGGACTGGTCCTCAACAGCTTCGGGCTCTTCGTATCACTGCATGACGCGTTCTGGGGCGCGGT
GGCCGGCTACATGGCGCTGTGGACGGTGTTCTGGCTGTTCAAGCTGGTCACCGGCAAGGACGGCATCGGTTACGGTGACT
TCAAGCTCCTGGCGATGCTCGGCGCCTGGGGCGGCTGGCAGATCCTGCCCATGACCATTCTGCTGTCATCGCTGGTAGGG
GCCATTCTCGGGGTGATTTTGCTGCGCCTGCGGGATGCGAAAACCTCGACGCCGCTACCCTTTGGACCCTATCTGGCCAT
TGCCGGCTGGATTGCCTTGCTCTGGGGTGGTCAAATAACCGGCTTCTATTGGCAGTTTGTCGGTTTGAAATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (20-126)

• Type IV leader peptidase family (Peptidase_A24) (136-245)

3D structure

• AlphaFold DB: A0A2W7LA92

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	53.191	97.241	0.517
pilD	Vibrio campbellii strain DS40M4	51.773	97.241	0.503
pilD	Acinetobacter baumannii D1279779	48.913	95.172	0.466
pilD	Acinetobacter nosocomialis M2	48.375	95.517	0.462
pilD	Neisseria gonorrhoeae MS11	47.778	93.103	0.445