Detailed information NTG0141165

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: FORC12_RS03910
• Genome accession: NZ_CP010998
• Coordinates: 783725..784036 (-)
• Length: 103 a.a.
• NCBI ID: WP_000472256.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain FORC_012 isolate human sputum
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 778725..789036

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FORC12_RS03875 (FORC12_0723)	gcvPA	779227..780573 (-)	1347	WP_000019681.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-
FORC12_RS03880 (FORC12_0724)	gcvT	780593..781684 (-)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
FORC12_RS03885 (FORC12_0725)	-	781843..782367 (-)	525	WP_001015121.1	shikimate kinase	-
FORC12_RS03890	-	782357..782503 (-)	147	WP_001789879.1	hypothetical protein	-
FORC12_RS03895 (FORC12_0726)	comGF	782600..783097 (-)	498	WP_020978197.1	competence type IV pilus minor pilin ComGF	Machinery gene
FORC12_RS03900 (FORC12_0727)	comGE	783015..783314 (-)	300	WP_000844410.1	hypothetical protein	Machinery gene
FORC12_RS03905 (FORC12_0728)	comGD	783301..783747 (-)	447	WP_001788899.1	competence type IV pilus minor pilin ComGD	Machinery gene
FORC12_RS03910 (FORC12_0729)	comGC	783725..784036 (-)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
FORC12_RS03915 (FORC12_0730)	comGB	784050..785120 (-)	1071	WP_000776401.1	competence type IV pilus assembly protein ComGB	Machinery gene
FORC12_RS03920 (FORC12_0731)	comGA	785092..786066 (-)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
FORC12_RS03925 (FORC12_0732)	-	786118..786741 (-)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
FORC12_RS03930 (FORC12_0733)	-	786738..787067 (-)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
FORC12_RS03935 (FORC12_0734)	-	787067..788053 (-)	987	WP_000161314.1	ROK family glucokinase	-
FORC12_RS03940	-	788050..788253 (-)	204	WP_000087561.1	YqgQ family protein	-

Sequence

Protein

• Length: 103 a.a.
• Molecular weight: 11315.36 Da
• Isoelectric Point: 8.5268

>NTDB_id=141165 FORC12_RS03910 WP_000472256.1 783725..784036(-) (comGC) [Staphylococcus aureus strain FORC_012 isolate human sputum]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide

• Length: 312 bp

>NTDB_id=141165 FORC12_RS03910 WP_000472256.1 783725..784036(-) (comGC) [Staphylococcus aureus strain FORC_012 isolate human sputum]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (6-30)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus MW2	100	100	1
comGC	Staphylococcus aureus N315	100	100	1
comGC/cglC	Streptococcus pneumoniae TIGR4	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae Rx1	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae D39	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae R6	46.078	99.029	0.456
comGC/cglC	Streptococcus mitis SK321	51.163	83.495	0.427
comGC/cglC	Streptococcus mitis NCTC 12261	51.163	83.495	0.427
comYC	Streptococcus gordonii str. Challis substr. CH1	42.857	95.146	0.408
comYC	Streptococcus suis isolate S10	50	75.728	0.379
comGC	Bacillus subtilis subsp. subtilis str. 168	41.758	88.35	0.369
comGC	Lactococcus lactis subsp. cremoris KW2	46.341	79.612	0.369