Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   QI18_RS09225 Genome accession   NZ_CP010050
Coordinates   1873022..1873723 (-) Length   233 a.a.
NCBI ID   WP_004255173.1    Uniprot ID   S6FFV7
Organism   Lactococcus lactis subsp. lactis strain S0 isolate fresh raw milk     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1868022..1878723
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QI18_RS09205 (QI18_09205) - 1868132..1869349 (-) 1218 WP_039115846.1 cysteine desulfurase -
  QI18_RS09210 (QI18_09210) sufD 1869349..1870605 (-) 1257 WP_039115848.1 Fe-S cluster assembly protein SufD -
  QI18_RS09215 (QI18_09215) sufC 1870743..1871513 (-) 771 WP_004255181.1 Fe-S cluster assembly ATPase SufC -
  QI18_RS09220 (QI18_09220) - 1871688..1873019 (-) 1332 WP_039115851.1 glycosyltransferase family 4 protein -
  QI18_RS09225 (QI18_09225) mecA 1873022..1873723 (-) 702 WP_004255173.1 adaptor protein MecA Regulator
  QI18_RS09230 (QI18_09230) - 1873853..1874587 (-) 735 WP_039115854.1 amino acid ABC transporter ATP-binding protein -
  QI18_RS09235 (QI18_09235) - 1874587..1875273 (-) 687 WP_004255158.1 amino acid ABC transporter permease -
  QI18_RS09240 (QI18_09240) - 1875420..1876328 (-) 909 WP_039115860.1 diacylglycerol/lipid kinase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27077.46 Da        Isoelectric Point: 4.1246

>NTDB_id=133725 QI18_RS09225 WP_004255173.1 1873022..1873723(-) (mecA) [Lactococcus lactis subsp. lactis strain S0 isolate fresh raw milk]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=133725 QI18_RS09225 WP_004255173.1 1873022..1873723(-) (mecA) [Lactococcus lactis subsp. lactis strain S0 isolate fresh raw milk]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTTGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FFV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.571

100

0.996
  mecA Lactococcus lactis subsp. cremoris KW2

96.996

100

0.97

Multiple sequence alignment